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91.发明授权VERFAHREN UND VORRICHTUNG ZUR BEHANDLUNG VON MILCH, INSBESONDERE VON MUTTERMILCH 有权方法和一种用于治疗牛奶，尤其是母乳
公开(公告)号：EP1182934B8
公开(公告)日：2005-10-19
申请号：EP00935139.6
申请日：2000-05-29
IPC分类号： A23C1/00
摘要： According to the inventive method for treating milk, the milk is momentarily heated in a container (24). The container (24) is set in motion, at least while the milk is being heated, in such a way that a milk film (32) forms on the inner wall (29). The invention also relates to a device (10) for carrying out the method.
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公开(公告)号：EP1073487B1
公开(公告)日：2005-07-20
申请号：EP99915530.2
申请日：1999-02-20
IPC分类号： A61M1/02
CPC分类号： A61M1/0209 , A61M1/0218 , A61M1/029 , A61M2202/0427 , A61M2202/0439 , A61M2205/331 , A61M2202/0042 , A61M2202/0092 , A61M2202/0057
摘要： The invention relates to a method for producing a thrombocyte preparation (27) that is low in leucocytes and erythrocytes from a thrombocyte concentrate (26) containing leucocytes and a residual proportion of erythrocytes. The thrombocyte concentrate (26) is initially centrifuged. The thrombocyte concentrate is subsequently filtered using a leucocyte depletion filter (21), beginning with the centrifugal supernatant. The proportion of erythocytes in the thrombocyte concentrate (26) to be filtered is monitored (16) before passing through to the leucocyte depletion filter (21). The entire filter process is terminated when a specific proportion of erythrocytes is obtained.
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93.发明公开
公开(公告)号：EP1537148A1
公开(公告)日：2005-06-08
申请号：EP03794994.8
申请日：2003-09-05
发明人： BÜHRING, Hans-Jörg , VOGEL, Wichard
IPC分类号： C07K16/28 , C12N5/06 , G01N33/577 , A61K39/395
CPC分类号： C07K16/28 , G01N33/56966 , G01N33/6896
摘要： The invention relates to monoclonal antibodies or the fragments thereof which make it possible to isolate and/ or identify neuronal precursor cells. Said antibodies or the fragments thereof are bounded with an antigen similar to an antibody produced by cellular lines of hibridoma deposited 14.08.2002 under numbers DSM ACC2571, DSM ACC2570 and DSM ACC2568.
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94.发明公开
公开(公告)号：EP1513539A1
公开(公告)日：2005-03-16
申请号：EP03760597.9
申请日：2003-06-07
发明人： HAMPRECHT, Klaus , JAHN, Gerhard , SCHOTT, Herbert
IPC分类号： A61K31/7072 , A61K31/047 , A61P31/12
CPC分类号： A61K31/7072 , A61K31/047
摘要： The invention relates to the use of an amphiphilic nucleoside phosphonoformic acid derivative comprising an esterified or non-esterified carboxyl group, preferably of a nucleoside glycerol (hydroxycarbonyl) phosphonate, as an active substance for the production of a medicament used for treating infectious diseases which are caused by human pathogenic viruses.
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95.发明授权A3C6E2, ein monoklonaler Antikörper spezifisch für den humanen Stammzellfaktor (SCF)-Rezeptor 失效A3C6E2，特异于人干细胞因子的单克隆抗体（SCF）受体
公开(公告)号：EP0787743B1
公开(公告)日：2004-10-13
申请号：EP96118320.9
申请日：1996-11-15
IPC分类号： C07K16/28 , C12N5/18 , A61K39/395 , G01N33/53
CPC分类号： G01N33/56972 , A61K38/00 , C07K16/2863
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公开(公告)号：EP0863157B8
公开(公告)日：2004-09-08
申请号：EP97122273.2
申请日：1997-12-17
IPC分类号： C07K16/28 , C12N5/20 , G01N33/577 , G01N33/574 , A61K39/395 , A61P35/02
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公开(公告)号：EP1332218A1
公开(公告)日：2003-08-06
申请号：EP01993692.1
申请日：2001-10-31
CPC分类号： C12N15/62 , C07K2319/60 , C12Q1/6897
摘要： The invention relates to a DNA construct that contains a fusion gene under the control of a promoter. The fusion gene comprises at least one resistance gene and at least one reporter gene and is slightly toxic to a host cell transfected with the DNA construct. The DNA construct can be encoded on a plasmid or a virus. The invention further relates to a method for using the DNA construct to identify substances that may induce differentiation in eukaryotic cells.
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公开(公告)号：EP1244707A1
公开(公告)日：2002-10-02
申请号：EP00979567.5
申请日：2000-11-16
申请人： Eberhard-Karls-Universität Tübingen Universitätsklinikum , Max-Planck-Gesellschaft zur Förderungder Wissenschaften e.V.
IPC分类号： C07K16/18 , A61K39/395 , G01N33/53 , C12N5/20 , A61K47/48 , G01N33/577 , G01N33/68
CPC分类号： C07K16/18 , A61K2039/505
摘要： The invention relates to monoclonal antibodies which specifically bind to the extracellular domains of the cell surface glycoproteins SIRP and in certain cases block the interaction of SIRP with the CD47 surface molecule.
摘要翻译： 描述了特异性结合SIRP细胞表面糖蛋白的细胞外结构域，并且在某些情况下阻止SIRP与表面分子CD47的相互作用的单克隆抗体。
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公开(公告)号：EP1214408A1
公开(公告)日：2002-06-19
申请号：EP99948829.9
申请日：1999-09-22
IPC分类号： C12N15/11 , C12N9/00 , C12N15/86 , A61K31/713 , A61K48/00
CPC分类号： C12N15/113 , A61K38/00 , A61K48/00 , C12N2310/111 , C12N2310/121
摘要： The invention relates to a catalytically active RNA molecule that is directed to mRNA molecules that encode the cell cycle relevant proteins cyclin E or E2F1. The catalytically active RNA molecule is a hammerhead ribozyme that induces the inhibition of the cell cycle of vascular smooth muscle cells in order to prevent restenosis.
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公开(公告)号：EP1210439A1
公开(公告)日：2002-06-05
申请号：EP00949478.2
申请日：2000-08-10
IPC分类号： C12N15/41 , C07K14/085 , A61K48/00
CPC分类号： C12N15/86 , A61K48/00 , C12N2770/32343 , C12N2830/38 , C12N2840/203
摘要： The invention relates to a recombinant RNA molecule that can at least partially be translated in a target cell and that contains a non-infectious Coxsackie virus group B virus genome, preferably of the B3 serotype, and at least one foreign gene that induces a desired function in the target cell, for example within the context of a genetic therapy. The RNA molecule can be encoded by a vector plasmid and/or can be packaged as a genome into a virion by which the target cell can then be infected. The invention further relates to methods for producing the RNA molecule, the virions and the vector plasmid, and to corresponding kits.
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