公开(公告)号：EP2536413A1

公开(公告)日：2012-12-26

申请号：EP11712922.1

申请日：2011-02-16

申请人： Laboratoires Urgo

发明人： APERT, Laurent ,  LAURENSOU, Christelle ,  NICOT, Dominique

IPC分类号： A61K31/70 ,  A61F13/00 ,  A61P17/02 ,  A61K31/7016 ,  A61K31/702

CPC分类号： A61L15/18 ,  A61F13/00 ,  A61K31/155 ,  A61K31/167 ,  A61K31/7016 ,  A61K31/702 ,  A61K31/7024 ,  A61K45/06 ,  A61L15/28 ,  A61L15/44 ,  A61L15/60 ,  A61L2300/232 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/45 ,  A61K2300/00

摘要： The present invention relates to the use of at least one compound selected among the synthetic polysulphated oligosaccharides having 1 to 4 ose units and to the salts and complexes thereof as cleaning agents for a wound. The invention can be used in particular for preparing bandages intended for cleaning wounds.

摘要翻译： 本发明涉及至少一种选自具有1至4个单位的合成多硫酸寡糖的化合物及其盐和复合物作为伤口清洁剂的用途。 本发明特别可用于制备用于清洁伤口的绷带。

公开(公告)号：EP2387390B1

公开(公告)日：2012-11-28

申请号：EP10700405.3

申请日：2010-01-12

申请人： PharmaSurgics in Sweden AB

发明人： MAHLAPUU, Margit ,  MÜNNICH, Mattias ,  SJÖSTRAND, Veronika

IPC分类号： A61K9/06 ,  A61K31/728 ,  A61K38/40 ,  A61K45/06 ,  A61L31/16 ,  A61K38/00 ,  A61K9/00 ,  A61K47/36

CPC分类号： A61K38/40 ,  A61K9/0014 ,  A61K9/06 ,  A61K31/728 ,  A61K38/08 ,  A61K38/10 ,  A61K45/06 ,  A61K47/36 ,  A61L31/16 ,  A61L2300/232 ,  A61L2300/252 ,  A61K2300/00

摘要： Pharmaceutical compositions are provided for enhancing the therapeutic effect of biologically active peptides, especially peptides derived from human lactoferrin. The compositions are useful for the treatment and/or prevention of wounds, scars, and post surgical adhesions.

公开(公告)号：EP2473200A2

公开(公告)日：2012-07-11

申请号：EP10748093.1

申请日：2010-09-01

申请人： Medovent GmbH

发明人： MONTENEGRO, Rivelino ,  FREIER, Thomas

IPC分类号： A61L15/16 ,  A61L26/00 ,  A61L15/28

CPC分类号： A61L26/0023 ,  A61L15/28 ,  A61L26/0066 ,  A61L2300/232 ,  A61L2300/404 ,  C08L5/08

摘要： A kit comprising a tissue dressing material for being applied in contact with the tissue of a patient and a detachment solvent for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a water-soluble tissue dressing material in contact with the patient's tissue; and applying an acidic detachment solvent to the tissue dressing material for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a liquid tissue dressing material in contact with the patient's tissue; and applying a detachment solvent to the tissue dressing material for removing the tissue dressing material from the tissue. A method of treating a tissue of a patient, the method comprising the steps of: applying a water-soluble tissue dressing material in contact with the patient's tissue; and allowing the water-soluble tissue dressing material to convert into a form in which it is insoluble in water at neutral pH. And a solid material comprising a polymer salt and glycerol, the glycerol content being at least 10% of the polymer salt content by weight, for use in a method of treating a human or animal tissue.

公开(公告)号：EP2013237A4

公开(公告)日：2012-06-27

申请号：EP07757188

申请日：2007-02-19

申请人： ENDOMEDIX INC

发明人： CHEN WEILIAM ,  ABRAHAMS JOHN M

IPC分类号： C08B37/08 ,  A61K9/14 ,  A61L24/04

CPC分类号： A61L26/0052 ,  A61K9/0085 ,  A61K9/06 ,  A61K31/721 ,  A61K31/722 ,  A61K38/1875 ,  A61K47/60 ,  A61K47/6903 ,  A61K48/00 ,  A61K49/0002 ,  A61K49/0457 ,  A61K51/1213 ,  A61L24/0031 ,  A61L24/043 ,  A61L24/08 ,  A61L24/104 ,  A61L26/0066 ,  A61L26/008 ,  A61L26/009 ,  A61L2300/232 ,  A61L2300/236 ,  C08L89/00 ,  C08L5/08

摘要： A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises alkylated chitosan or a gelatin, and a polybasic carboxylic acid or an oxidized polysaccharide, in an aqueous medium. The premix can also include a dehydrating reagent, a carboxyl activating reagent, or both. A specific use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug.

摘要翻译： 提供了用于外科和医疗程序中用于密封活体哺乳动物的组织的组织密封剂。 组织密封剂包括通过凝胶化设置在待密封组织上的预混物形成的水凝胶。 预混物在水性介质中包含烷基化壳聚糖或明胶，以及多元羧酸或氧化多糖。 预混物还可以包括脱水剂，羧基活化剂或二者。 组织密封剂的具体用途是在脑外科手术后修复硬脑膜，以防止脑脊液漏出。 组织密封剂可以包括治疗剂或保护剂，例如抗生素或抗炎药。

公开(公告)号：EP2411067A1

公开(公告)日：2012-02-01

申请号：EP10713047.8

申请日：2010-03-26

申请人： Seventh Sense Biosystems, Inc.

发明人： LEVINSON, Douglas, A. ,  LANGER, Robert, S.

IPC分类号： A61L27/50

CPC分类号： A61L27/50 ,  A61B1/042 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1473 ,  A61B5/411 ,  A61B5/4504 ,  A61B5/6846 ,  A61F2002/488 ,  A61L27/54 ,  A61L2300/232 ,  A61L2300/252 ,  A61L2300/442

摘要： The present invention generally relates to implants and, in particular, to systems and methods for monitoring the condition of an implant within a subject. In some embodiments, an implant may be prepared that contains a tracer. After implantation, the tracer from the implant may be determined within a subject using any suitable method, depending on the tracer. As an example, the tracer may be determined by administering an indicator able to interact with the tracer to the subject. For instance, the indicator may be applied to the skin of the subject, and the indicator may give a different visual appearance based on the tracer, or otherwise exhibits a determinable change in a property of the indicator. Other aspects of the invention are generally directed to methods of making or using implants, methods of promoting the making or use of such implants, kits involving such implants, or the like.

公开(公告)号：EP2111876B1

公开(公告)日：2011-09-07

申请号：EP09010135.3

申请日：1996-12-18

申请人： AngioDevice International GmbH

发明人： Rhee, Woonza, M.

IPC分类号： A61L24/04 ,  A61L27/34 ,  A61L27/54 ,  A61L31/06 ,  A61L31/08 ,  A61L31/16 ,  C08L81/00

CPC分类号： A61L31/16 ,  A61L24/043 ,  A61L24/08 ,  A61L27/26 ,  A61L27/34 ,  A61L27/54 ,  A61L31/041 ,  A61L2300/232 ,  A61L2300/252 ,  A61L2300/606 ,  C08B37/0075 ,  C08G65/329 ,  C08H1/00 ,  C08H1/06 ,  C08L71/02 ,  Y10S623/90 ,  Y10S623/901 ,  C08L5/16 ,  C08L71/00

公开(公告)号：EP1375537B1

公开(公告)日：2010-04-21

申请号：EP03021645.1

申请日：1999-05-28

申请人： Evonik Stockhausen GmbH

发明人： Bruhn, Christoph ,  Herrmann, Edgar, Dr. ,  Issberner, Jörg, Dr. ,  Kersten, Dagmar ,  Mertens, Richard, Dr. ,  Werner, Georg

IPC分类号： C08F20/04 ,  C08F251/00 ,  A61L15/00

CPC分类号： C08L51/02 ,  A61L15/20 ,  A61L15/46 ,  A61L15/60 ,  A61L2300/232 ,  A61L2300/802 ,  C08F8/00 ,  C08F20/04 ,  C08F251/02 ,  C08F261/04 ,  C08F265/02 ,  C08F265/04 ,  C08F291/00 ,  C08F2800/20 ,  C08F2810/20 ,  C08L51/003 ,  C09D151/003 ,  C09D151/02 ,  Y10T428/249953 ,  Y10T428/249954 ,  Y10T428/249958 ,  C08L2666/02 ,  C08F220/06

公开(公告)号：EP1469865A4

公开(公告)日：2010-04-14

申请号：EP02797532

申请日：2002-12-31

申请人： CROSSLINK D INC

发明人： COCHRUM KENT C ,  JEMTRUD SUSAN

IPC分类号： A61B17/12 ,  A61K31/715 ,  A61F20060101 ,  A61F13/00 ,  A61K31/718 ,  A61K31/721 ,  A61K31/729 ,  A61L15/00 ,  A61L15/16 ,  A61L15/28 ,  A61L17/00 ,  A61P7/04 ,  C08B1/00 ,  C08B30/00

CPC分类号： A61L33/08 ,  A61L15/225 ,  A61L15/28 ,  A61L15/44 ,  A61L2300/232 ,  A61L2300/418 ,  A61L2400/04 ,  C08L5/04 ,  C08L1/26 ,  C08L5/02

公开(公告)号：EP1937327A1

公开(公告)日：2008-07-02

申请号：EP06815123.2

申请日：2006-09-21

申请人： SurModics, Inc.

发明人： CHUDZIK, Stephen, J. ,  BURKSTRAND, Michael, J. ,  SWAN, Dale, G. ,  CHINN, Joseph, A.

IPC分类号： A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  A61L31/10

CPC分类号： A61L27/20 ,  A61K9/0024 ,  A61K9/0051 ,  A61K9/2027 ,  A61K9/205 ,  A61K47/34 ,  A61L27/34 ,  A61L27/54 ,  A61L27/58 ,  A61L29/085 ,  A61L29/16 ,  A61L31/042 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/232 ,  A61L2300/252 ,  A61L2300/258 ,  A61L2300/604 ,  A61L2300/606 ,  A61L2420/02 ,  B05D1/36 ,  B05D7/52 ,  C08B31/006 ,  C08B31/04 ,  C08B33/02 ,  C08B33/04 ,  C08L3/02 ,  C08L3/12 ,  C09D103/02 ,  C09D103/18

摘要： Matrices formed from a natural biodegradable material and that exhibit surface degradation in the presence of an enzyme are described. Matrices including a bioactive agent can be implanted or formed in a subject for release of the bioactive agent upon degradation of the matrix. The matrix can be provided in various forms, including coatings for implantable devices, implants, and in-situ formed matrices. The matrix can also be in the form of a medical device having a structure that is used to treat a medical condition.

公开(公告)号：EP1807132A1

公开(公告)日：2007-07-18

申请号：EP05824218.1

申请日：2005-11-01

申请人： Accessclosure, Inc.

发明人： KHOSRAVI, Farhad ,  PAI, Suresh, S. ,  BAGAOISAN, Celso, J.

IPC分类号： A61L31/14 ,  A61L27/52

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00004 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61B2017/00654 ,  A61K9/0024 ,  A61L26/0052 ,  A61L26/008 ,  A61L27/58 ,  A61L31/042 ,  A61L31/044 ,  A61L31/046 ,  A61L31/048 ,  A61L31/06 ,  A61L31/145 ,  A61L31/148 ,  A61L2300/232 ,  A61L2300/252 ,  A61L2300/418 ,  A61L2300/606 ,  A61L2400/04 ,  A61L2420/06 ,  C08L71/02

摘要： The present invention relates to a device (2) for sealing a puncture extending through tissue, comprising a carrier (4) in a predetermined shape, further characterized by a first hydrogel precursor (6) disposed at least partially on an exterior surface of the carrier; a second hydrogel precursor (7) disposed on the exterior surface of the carrier, the first and second precursors remaining in an unreactive state on the carrier prior to exposure to an aqueous physiological environment, whereupon the first and second precursors react to form a hydrogel.