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公开(公告)号：EP1591111A1
公开(公告)日：2005-11-02
申请号：EP04705178.4
申请日：2004-01-26
发明人： SHIRAI, Sadanobu
CPC分类号： A61K9/7061
摘要： A thin aqueous cataplasm prepared by laminating an adhesive layer (base) having specified constituents on a support which consists of a fiber film prepared by heat-fusing a soft plastic resin on a composite fiber prepared by entangling a natural fiber and a soft plastic fiber, or consists of a fiber film prepared by heat-fusing a plastic resin having a soft part and a hard part in common on a fiber consisting of a plastic having a soft part and hard part in common.
The thin aqueous cataplasm retains a moisture-protecting effect on the skin and provides comfortable feeling in its use.-
公开(公告)号：EP1547600A1
公开(公告)日：2005-06-29
申请号：EP03784555.9
申请日：2003-08-07
IPC分类号： A61K31/565 , A61K9/70 , A61K47/14 , A61K47/16 , A61K47/32 , A61P3/06 , A61P9/10 , A61P15/12 , A61P19/10 , A61P25/28 , A61P43/00
CPC分类号： A61K9/7061 , A61K9/0014 , A61K31/57 , A61K47/14
摘要： Provided herein is a female hormone-containing patch wherein an active ingredient is highly soluble in a pressure-sensitive adhesive layer and the active ingredient is not adsorbed to a backing, and the patch per se can follow the irregularities on the skin surface or body movements. The patch is an external patch containing, as a female hormone, a follicular hormone estradiol and/or its derivative or a progestational hormone norethisterone and/or its derivative. The external patch comprises an acrylic pressure-sensitive adhesive containing 0.01 to 1% by weight of an isocyanate-based crosslinking agent as an essential ingredient.
摘要翻译： 本文提供了一种含雌激素的贴剂，其中活性成分高度可溶于压敏粘合剂层，并且活性成分不吸附到背衬上，并且贴剂本身可以遵循皮肤表面上的不规则或身体运动 。 补片是含有雌激素，卵泡激素雌二醇和/或其衍生物或孕激素炔诺酮和/或其衍生物的外部补片。 外部贴片包含含有0.01〜1重量％的异氰酸酯系交联剂作为必要成分的丙烯酸类压敏粘合剂。
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173.发明公开
公开(公告)号：EP1538200A1
公开(公告)日：2005-06-08
申请号：EP03752940.1
申请日：2003-05-22
申请人： Fushimi Pharmaceutical Company, Limited , Teikoku Seiyaku Co., Ltd. , Kagawa University , Shikoku Research Institute Incorporated , KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO
发明人： IZUMORI, Ken , TOKUDA, Masaaki , ITANO, Toshifumi , MIYAMOTO, Osamu , ISHIDA, Toshihiko , MURAO, Koji , TASAKA, Taizo , MUNEUCHI, Gan , YAMAGUCHI, Fuminori , TANAKA, Terukazu , HOSSAIN, Mohammad, Akram , UEKI, Masaaki , HIROOKA, Kazuyuki , TAMINATO, Tomohiko , TSUSAKI, Keiji , TAKAHASHI, Takeo , NAGATA, Mitsuhiro , ISHIDA, Yutaka
IPC分类号： C12N5/08 , A23L1/30 , A61K7/00 , A61K31/7004
CPC分类号： A61Q19/00 , A23L5/00 , A23L29/30 , A23L33/10 , A23L33/125 , A61K8/60 , A61K31/7004
摘要： A method of utilizing the physiological activity of a rare saccharide, wherein physiological-activity sensitive cells are treated with the rare saccharide to modify the function of the cells. A composition containing, as an active ingredient, a rare saccharide which is introduced into physiological-activity sensitive cells and has an effect of modifying the function of the cells. The cells are human cells. The composition is a functional food, a drug, or a cosmetic. The rare saccharide is a rare saccharide belonging to aldose and/or ketose. The aldose is D-allose, and the cells are selected from the group consisting of cancer-cell proliferation inhibitory activity sensitive cells and active-oxygen production inhibitory activity sensitive cells. The ketose is D-psicose, and the cells are selected from the group consisting of chemokine secretion inhibitory activity sensitive cells, microglia migration inhibitory activity sensitive cells, and hypoglycemic activity sensitive cells.
摘要翻译： 利用一种罕见糖的生理活性的方法，worin生理活性敏感细胞与罕见糖处理，以改变细胞的功能。 被引入生理活性敏感的细胞，并且对修饰细胞功能的影响包含组合物，如在，稀有糖类活性成分全部。 该细胞是人类细胞。 该组合物是一种功能性食品，药物或化妆品。 稀有糖类是属于醛糖和/或酮糖罕见的糖。 醛糖是D-阿洛糖，并将细胞选自癌细胞增殖抑制活性敏感的细胞和活性氧产生抑制活性敏感的细胞的选择。 所述酮糖是D-阿洛酮糖，并且所述细胞选自趋化因子分泌的抑制活性敏感的细胞，小神经胶质细胞迁移抑制活性敏感的细胞，和低血糖活性敏感的细胞的选择。
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174.发明公开A stable external preparation containing aspirin 失效Stabile Zubereitung enthaltendAcetylsalicylsäureundSiliconölzuräusserenAnwendung
公开(公告)号：EP1273300A2
公开(公告)日：2003-01-08
申请号：EP02021780.8
申请日：1998-06-23
CPC分类号： A61K9/0014 , A61K9/7053 , A61K9/7061 , A61K9/7076 , A61K31/616 , A61K47/06 , A61K47/14 , A61K47/18 , A61K47/34 , A61K47/44
摘要： External preparations containing Aspirin which are stored for a long term and superior in dermal absorbability.
The preparations are prepared by mixing Aspirin together with silicon oil.摘要翻译： 含有阿司匹林的外用制剂，其长期储存并具有优异的皮肤吸收性。 通过将阿司匹林与硅油混合制备制剂。
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公开(公告)号：EP1151751A1
公开(公告)日：2001-11-07
申请号：EP00953432.2
申请日：2000-08-11
发明人： SYUDO, Jutaro
IPC分类号： A61K31/375 , A61K9/70 , A61K7/00
CPC分类号： A61L15/44 , A61K8/0208 , A61K8/042 , A61K8/26 , A61K8/676 , A61K9/7007 , A61K9/7053 , A61K9/7061 , A61K31/375 , A61K33/14 , A61L2300/428 , A61Q19/00 , Y10S514/944 , A61K33/12 , A61K33/08 , A61K2300/00
摘要： A cataplasm comprising crosslinked polymer gel containing vitamin C or a derivative thereof and a support, wherein the gel is formed by crosslinking a polymer with two kinds of substances selected from magnesium aluminometasilicate, dried aluminum hydroxide gel and aluminum chloride is prepared.
摘要翻译： 制备包含含有维生素C或其衍生物的交联聚合物凝胶和载体的粘膜，其中通过将聚合物与两种选自硅铝酸镁，干燥的氢氧化铝凝胶和氯化铝的物质交联而形成凝胶。
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176.发明公开OILY PATCHES FOR EXTERNAL USE CONTAINING DICLOFENAC SODIUM 失效ÖLIGEPFLASTER MIT NA-DICLOFENAC ZURÄUSSERENANWENDUNG
公开(公告)号：EP0950408A1
公开(公告)日：1999-10-20
申请号：EP98931077.6
申请日：1998-07-14
CPC分类号： A61K9/7053 , A61K9/7076 , A61K31/196 , A61K47/12
摘要： Oily patches for external use of diclofenac sodium characterized by a blend of diclofenac sodium, isostearic acid and C 10-18 fatty acids which are liquid at ordinary temperature with sticky bases.
摘要翻译： 用于外用双氯芬酸钠的油性贴剂，其特征在于双氯芬酸钠，异硬脂酸和C10-18脂肪酸的混合物，其在常温下为粘性碱。
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公开(公告)号：EP0436217B1
公开(公告)日：1995-04-05
申请号：EP90125524.0
申请日：1990-12-27
CPC分类号： A61K9/7061 , A61K9/0014 , A61K31/19 , A61K47/12 , A61K47/18
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178.发明公开External anti-inflammatory and analgesic plaster preparation 失效Entzündungshemmendesund analgetischesäusserlichesPflaster-Präparat。
公开(公告)号：EP0621263A2
公开(公告)日：1994-10-26
申请号：EP94106189.7
申请日：1994-04-21
发明人： Akazawa, Mitsuji
IPC分类号： C07C229/42 , C07D295/088 , A61K9/70
CPC分类号： C07D295/088 , A61K9/7053 , A61K9/7061 , Y10S514/887
摘要： An external anti-inflammatory and analgesic plaster preparation includes as an active ingredient a salt of diclofenac, 2[(2,6-dichlorophenyl)amino]benzene-acetic acid, with a cyclic organic having the general formula (I):
wherein X is a group of the formula -(CH₂)m- in which m is an integer of 0 or 1 and n is an integer of 2 and a pH value of the preparation is adjusted to a range of 7.3 to 9.0.摘要翻译： 外用消炎镇痛药剂包括作为活性成分的双氯芬酸盐，2 [（2,6-二氯苯基）氨基]苯 - 乙酸与具有通式（I）的环状有机物的盐：
其中X是式 - （CH2）m-的基团，其中m是0或1的整数，n是2的整数，并且将制剂的pH值调节到7.3-9.0的范围。 -
公开(公告)号：EP0332222A3
公开(公告)日：1991-03-06
申请号：EP89104440.6
申请日：1989-03-13
发明人： Takeru, Fujii , Seiichi, Sako , Shigeyuki, Takama Fukuari Danchi no. 214 , Toru, Hibi , Akiya, Yamada
CPC分类号： A61K47/42 , A61K9/0034 , A61K47/10 , A61K47/12 , A61K47/20
摘要： Pharmaceutical compositions of matter adapted for intravaginal administration comprise a biologically active polypeptide, an absorption promoter, such as an anionic and/or nonionic surfactant or a nonionic surfactant and an aliphatic carboxylic acid, optionally an animal and/or vegetable protein and a nontoxic pharmaceutically acceptable carrier or diluent therefor, in a formulation suitable for intravaginal administration. Preferred compositions comprise calcitonin as the biologically active polypeptide. Preferred absorption promoters are anionic surfactants, e.g., sodium lauryl sulfate, and the combination absorption promoter of a nonionic surfactant and a medium chain aliphatic carboxylic acid or its salt, e.g. polyoxyethylenealkylphenylether and a medium chain aliphatic carboxylic acid.
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