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11.发明公开
公开(公告)号：EP3998079A1
公开(公告)日：2022-05-18
申请号：EP21199061.9
申请日：2015-06-03
发明人： WANG, Changyu , LONBERG, Nils , KORMAN, Alan J. , SELBY, Mark J. , SRINIVASAN, Mohan , HENNING, Karla , HAN, Michelle Minhua , CHEN, Guodong , HUANG, Richard , CHAKRABORTY, Indrani , HUANG, Haichun , WONG, Susan , LI, Huiming
摘要： Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
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公开(公告)号：EP3304079B1
公开(公告)日：2020-06-03
申请号：EP16731700.7
申请日：2016-06-02
发明人： WANG, Xi-tao , ADELAKUN, Olufemi, A. , LEWIN, Anne, C. , KORMAN, Alan, J. , SELBY, Mark, J. , WANG, Changyu , HUANG, Haichun , HENNING, Karla, A. , LONBERG, Nils , SRINIVASAN, Mohan , HAN, Michelle, Minhua , CHEN, Guodong , HUANG, Richard , CHAKRABORTY, Indrani , WONG, Susan, Chien-Szu , LI, Huiming
IPC分类号： G01N33/566 , C07K16/28
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13.发明授权
公开(公告)号：EP3151921B1
公开(公告)日：2019-08-28
申请号：EP15742414.4
申请日：2015-06-03
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