公开(公告)号：EP3304079A1

公开(公告)日：2018-04-11

申请号：EP16731700.7

申请日：2016-06-02

申请人： Bristol-Myers Squibb Company

发明人： WANG, Xi-tao ,  ADELAKUN, Olufemi, A. ,  LEWIN, Anne, C. ,  KORMAN, Alan, J. ,  SELBY, Mark, J. ,  WANG, Changyu ,  HUANG, Haichun ,  HENNING, Karla, A. ,  LONBERG, Nils ,  SRINIVASAN, Mohan ,  HAN, Michelle, Minhua ,  CHEN, Guodong ,  HUANG, Richard ,  CHAKRABORTY, Indrani ,  WONG, Susan, Chien-Szu ,  LI, Huiming

IPC分类号： G01N33/566 ,  C07K16/28

摘要： Provided herein are diagnostic antibodies that bind to glucocorticoid-induced tumor necrosis factor receptor (GITR). Such antibodies are useful for methods of detecting the expression of GITR in biological samples, for example, tumor tissue, and identifying a cancer patient likely to respond to anti-GITR immunotherapy or predicting whether a cancer patient will respond to anti-GITR immunotherapy.

公开(公告)号：EP3304079B1

公开(公告)日：2020-06-03

申请号：EP16731700.7

申请日：2016-06-02

申请人： Bristol-Myers Squibb Company

发明人： WANG, Xi-tao ,  ADELAKUN, Olufemi, A. ,  LEWIN, Anne, C. ,  KORMAN, Alan, J. ,  SELBY, Mark, J. ,  WANG, Changyu ,  HUANG, Haichun ,  HENNING, Karla, A. ,  LONBERG, Nils ,  SRINIVASAN, Mohan ,  HAN, Michelle, Minhua ,  CHEN, Guodong ,  HUANG, Richard ,  CHAKRABORTY, Indrani ,  WONG, Susan, Chien-Szu ,  LI, Huiming

IPC分类号： G01N33/566 ,  C07K16/28