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公开(公告)号：EP2275205A3
公开(公告)日：2017-11-15
申请号：EP10169500.5
申请日：2010-07-14
申请人： SYSMEX CORPORATION
发明人： Ueda, Sachiko , Mori, Yusuke , Ohashi, Hiroyuki , Itose, Yuji , Uchihashi, Kinya , Nakamura, Yoichi , Sugitani, Kohei
CPC分类号： B01L3/0293 , B01L3/527 , B01L9/00 , B01L2200/185 , B01L2300/021 , G01N35/1002
摘要： A reagent container set is disclosed which comprises:
a first reagent container for accommodating a first reagent to be used in a sample analyzer, the top part of the first reagent container having a first aspiration opening for inserting a first reagent aspirating tube to aspirate the first reagent;
a waste fluid container for accommodating the first reagent used in the sample analyzer as a waste fluid, the top of the waste fluid container having a discharge opening for inserting a waste fluid discharging tube to discharge the waste fluid into the waste fluid container;
a box for accommodating the first reagent container and the waste fluid container; and
a container holding member for holding the first reagent container and the waste fluid container so that the first aspiration opening and the discharge opening are disposed at predetermined positions, the container holding member being maintained at a predetermined position within the box.-
12.发明授权
公开(公告)号：EP2889620B1
公开(公告)日：2017-10-11
申请号：EP14198316.3
申请日：2009-04-28
申请人： Sysmex Corporation
IPC分类号： G01N33/50 , G01N33/569
CPC分类号： C12Q1/68 , G01N33/5094 , G01N33/56905 , G01N2333/44 , Y02A50/58
摘要： This blood analyzer includes a sample preparation portion preparing a first measurement sample containing a blood sample and a hemolytic agent and a second measurement sample containing the blood sample, the same hemolytic agent as the hemolytic agent and a staining agent and a control portion classifying white blood cells in the first measurement sample into at least four groups of monocytes, neutrophils, eosinophils and a group of the others on the basis of fluorescent information and two types of scattered light information generated by a light information generation portion and classifying blood cells in the second measurement sample into malaria-infected red blood cells and a group of the others on the basis of fluorescent information and scattered light information generated by the light information generation portion.
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13.发明授权A reagent for partially lysing a cell membrane of a red blood cell, a reagent for detecting malaria infected red blood cells, and a sample analyzing method for detecting malaria infected red blood cells 有权试剂用于检测疟疾感染红细胞细胞膜红细胞试剂的部分溶解，以及用于检测疟疾感染红细胞的样品的分析方法。
公开(公告)号：EP1715345B1
公开(公告)日：2013-12-04
申请号：EP06006120.7
申请日：2006-03-24
申请人： SYSMEX CORPORATION
IPC分类号： G01N33/569 , G01N33/80
CPC分类号： G01N33/80 , G01N33/56905 , Y02A50/58
摘要： A reagent for partially lysing a cell membrane of a red blood cell infected with a malaria parasite, comprising: a first surfactant which has predetermined lysing ability for the red blood cell membrane; and a second surfactant which has weaker lysing ability than that of the first surfactant; wherein the reagent has pH of 5 to 7 and osmotic pressure of 200 to 300 mOsm/kg·H 2 O; and wherein the reagent partially lyses the malaria infected red blood cell membrane such that a malaria parasite is retained in the red blood cell and fluorescent dye passes through the cell membrane, is disclosed. A reagent for detecting malaria infected red blood cells, and a sample analyzing method for detecting malaria infected red blood cells, are also disclosed.
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公开(公告)号：EP1887357A2
公开(公告)日：2008-02-13
申请号：EP07012709.7
申请日：2007-06-28
申请人： SYSMEX CORPORATION
CPC分类号： G01N33/5094 , G01N33/56972 , G01N2015/008 , G01N2015/1486 , G01N2015/1497 , Y10T436/10 , Y10T436/101666
摘要： The present invention is to present a blood analyzer which can prevent an abnormal number of white blood cells caused by the lipid particles or the red blood cells of poor hemolysis from being output. The blood analyzer comprises: first white blood cell number obtaining means; second white blood cell number obtaining means; output means for outputting the number of the white blood cells obtained by the second white blood cell number obtaining means, and determining means for determining whether the number of the white blood cells obtained by the second white blood cell number obtaining means is abnormal, wherein the output means is configured to output the number of the white blood cells obtained by the first white blood cell number obtaining means when the determining means determines that the number of the white blood cells obtained by the second white blood cell number obtaining means is abnormal.
摘要翻译： 本发明是提供一种可以防止由脂质颗粒引起的异常数量的血液分析仪或者溶血不良的红细胞输出的血液分析装置。 血液分析装置包括：第一白细胞数获取装置; 第二白细胞数获得装置; 用于输出由第二白细胞数获得装置获得的白细胞数的输出装置，以及用于确定由第二白细胞数获得装置获得的白细胞数是否异常的确定装置，其中， 输出装置被配置为当确定装置确定由第二白细胞数获得装置获得的白细胞数异常时，输出由第一白细胞数获得装置获得的白细胞数。
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15.发明授权
公开(公告)号：EP0872734B1
公开(公告)日：2001-03-14
申请号：EP98106911.5
申请日：1998-04-16
申请人： Sysmex Corporation
CPC分类号： G01N33/5094 , G01N33/721 , Y10T436/10 , Y10T436/101666 , Y10T436/107497 , Y10T436/108331 , Y10T436/25 , Y10T436/25125 , Y10T436/2525
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公开(公告)号：EP2735859B1
公开(公告)日：2020-02-12
申请号：EP13193634.6
申请日：2013-11-20
申请人： SYSMEX CORPORATION
发明人： Kimura, Konobu , Uchihashi, Kinya
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公开(公告)号：EP2275205B1
公开(公告)日：2019-03-20
申请号：EP10169500.5
申请日：2010-07-14
申请人： SYSMEX CORPORATION
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公开(公告)号：EP2735859A3
公开(公告)日：2018-01-03
申请号：EP13193634.6
申请日：2013-11-20
申请人： SYSMEX CORPORATION
发明人： Kimura, Konobu , Uchihashi, Kinya
摘要： A method for analyzing blood cells includes: preparing a measurement specimen for classifying white blood cells, by mixing a sample with a reagent in order to hemolyze red blood cells contained in the sample and to fluorescently stain nucleic acid in white blood cells contained in the sample; detecting, by flowing the prepared measurement specimen in a flow cell, fluorescence emitted from each blood cell in the measurement specimen and two types of scattered light at respective different angles, and obtaining a fluorescence signal and two types of scattered light signals; and classifying the white blood cells into at least four groups and detecting neoplastic lymphocytes, by performing analysis using at least three types of parameters based on the obtained fluorescence signal and two types of scattered light signals.
摘要翻译： 一种分析血细胞的方法包括：制备用于分类白细胞的测量样本，通过将样本与试剂混合以使包含在样本中的红细胞溶血并且荧光地染色样本中包含的白血细胞中的核酸 ; 通过使制备的测量样本在流动池中流动，测量从测量样本中的每个血球发射的荧光和两种各自不同角度的散射光，并且获得荧光信号和两种类型的散射光信号; 并且通过基于所获得的荧光信号和两种类型的散射光信号通过使用至少三种类型的参数执行分析来将白血细胞分类为至少四组并且检测肿瘤性淋巴细胞。
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公开(公告)号：EP2644273A3
公开(公告)日：2017-11-29
申请号：EP12197222.8
申请日：2012-12-14
申请人： SYSMEX CORPORATION
发明人： Mori, Yusuke , Uchihashi, Kinya , Mizuno, Yumiko
摘要： This container storing a washing solution for a blood analyzer includes a container body made of thermoplastic resin resistant against a chlorine-based washing solution and provided with an opening on an upper portion, a chlorine-based washing solution stored in the container body, and a multilayer film covering the opening. The multilayer film includes a seal layer heat-sealed to the container body thereby blocking the opening and a gas barrier layer arranged on the outer side of the seal layer.
摘要翻译： 容纳血液分析仪用清洗液的容器包括：容器主体，该容器主体由抗氯基清洗液的热塑性树脂制成，并且在上部设有开口;容器主体中储存的氯基清洗液;以及 覆盖开口的多层膜。 多层膜包括热密封到容器主体的密封层，从而阻塞开口和布置在密封层的外侧上的气体阻隔层。
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20.发明公开BLOOD ANALYZER, BLOOD ANALYZING METHOD, AND BLOOD ANALYZING PROGRAM 审中-公开BLUTANALYSATOR，BLUTANALYSEVERFAHREN UND BLUTANALYSEPROGRAMM
公开(公告)号：EP2957889A1
公开(公告)日：2015-12-23
申请号：EP15172056.2
申请日：2015-06-15
申请人： SYSMEX CORPORATION
发明人： Kimura, Konobu , Uchihashi, Kinya , Linssen, Jo , Saker, Jarob
CPC分类号： G01N33/49 , G01N15/1429 , G01N15/1459 , G01N21/51 , G01N21/6428 , G01N2015/008 , G01N2015/1006 , G01N2015/1402 , G01N2021/6439
摘要： A blood analyzer comprises a sample preparing part, a light source, a light receiving part, and a processing part configured to discriminate and count reactive B lymphocytes based on at least one of fluorescent light signals and forward scattered light signals.
摘要翻译： 血液分析仪包括样品制备部分，光源，光接收部分和被配置为基于荧光信号和前向散射光信号中的至少一个来区分和计数反应性B淋巴细胞的处理部分。
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