-
公开(公告)号：EP2004159A1
公开(公告)日：2008-12-24
申请号：EP07726945.4
申请日：2007-03-15
申请人： Biovitrum AB (publ)
IPC分类号： A61K31/045 , A61P37/06
CPC分类号： A61K31/045
摘要： The invention relates to methods and materials involved in treating autoimmune conditions. In particular, the invention relates to methods and compounds (and compositions including the compounds) involved in treating, preventing, or delaying the onset of autoimmune conditions. The compounds can include one or more isoprenoid units. The compounds can enhance NADPH oxidase activity.
-
12.发明授权Piperazinylpyrazines as serotonin 5-HT2C receptor modulators 有权Piperazinylpyrazine作为血清素5-HT 2C受体的调节剂
公开(公告)号：EP1645558B1
公开(公告)日：2008-06-11
申请号：EP05023471.5
申请日：2003-06-18
申请人： Biovitrum AB (publ)
发明人： Cernerud, Magnus , Lundström, Helena , Löfström, Claes , Pelcman, Margit , Fleck, Tom , Paptchikhine, Alexander , Andersson, Emma , Nygren, Alf
IPC分类号： C07D401/12 , C07D401/14 , A61P3/04 , A61P3/10
CPC分类号： C07D401/12 , C07D401/14
-
公开(公告)号：EP3131606B1
公开(公告)日：2021-05-19
申请号：EP15715743.9
申请日：2015-04-14
发明人： FRANSSON, Jonas , HIMBERT, Hans , REINIUS, Pelle
-
公开(公告)号：EP3288536A1
公开(公告)日：2018-03-07
申请号：EP16722558.0
申请日：2016-04-27
CPC分类号： A61K38/2006 , A61K9/0048 , A61K47/02 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/22 , A61K47/26 , A61P27/02 , A61P27/04 , A61P27/14 , A61K2300/00
摘要： The present invention relates to compositions comprising anakinra, buffer, and optionally at least one osmolyte and optionally further excipients. Further, the present invention relates to use of said compositions for treatment of for example ophthalmic disorders.
-
15.发明公开POLYPEPTIDES BINDING TO HUMAN COMPLEMENT C5 有权AN E TE TE TE TE TE TE TE TE TE TE TE TE DE DE DE DE DE DE DE DE DE
公开(公告)号：EP2817329A4
公开(公告)日：2015-09-02
申请号：EP13752233
申请日：2013-02-19
发明人： BERGHARD CHARLOTTA , BERGLUND MAGNUS , STRÖMBERG PATRIK , LINDBORG MALIN , GUNNERIUSSON ELIN , FELDWISCH JOACHIM
IPC分类号： C07K14/47 , A61K38/00 , A61K38/16 , C07K14/195 , C07K14/315
CPC分类号： A61K38/164 , A61K38/00 , A61K38/16 , C07K14/00 , C07K14/195 , C07K14/315 , C07K14/47
摘要： The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A X6X7EID X11LPNL X16X17X18QW X21AFIX25X26LX28D, and ii) an amino acid sequence which has at least 86% identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatments.
摘要翻译： 本发明涉及C5结合多肽，其包含C5结合基序BM，该基序由选自i）EX2X3X4A X6X7EID X11LPNL X16X17X18QW X21AFIX23X26LX28D的氨基酸序列组成，以及ii）与SEQ ID NO：1至少86％同一性的氨基酸序列 i）中定义的序列，其中多肽与C5结合。 本发明还涉及用于治疗的C5结合多肽，例如用于治疗C5相关病症，以及治疗方法。
-
16.发明公开IMPROVED FORMULATIONS OF RECOMBINANT HUMAN BILE SALT-STIMULATED LIPASE 审中-公开重组人脂肪酶GALLENSÄURESTIMULIERTER改进配方
公开(公告)号：EP2760467A1
公开(公告)日：2014-08-06
申请号：EP12835172.3
申请日：2012-09-25
发明人： EK, Vilhelm
CPC分类号： C12N9/96 , A23L33/40 , A61K9/0095 , A61K9/19 , A61K38/465 , A61K47/183 , A61K47/26 , C12N9/18 , C12N9/20 , C12Y301/01001 , C12Y301/01013
摘要： The present invention relates to improved formulations of recombinant human bile salt stimulated lipase (rhBSSL), including those suitable for forming a lyophilized formulation of rhBSSL, lyophilized formulations of rhBSSL per-se, unit dose forms of rhBSSL and reconstituted formulations of rhBSSL. The formulations of the present invention comprises rhBSSL, a crystalline bulking agent and an amorphous stabilizer that is a different chemical entity to said crystalline bulking agent. The formulations of the present invention have one or more desired properties, including those that relate to stability, decreased aggregation and/or formation of insoluble aggregates in solution. The lyophilized formulations of the present invention have pharmaceutical utility, particularly for the administration of rhBSSL to human infants.
-
公开(公告)号：EP2710126A1
公开(公告)日：2014-03-26
申请号：EP12785836.3
申请日：2012-05-15
发明人： STRÖMQUIST, Thomas , WOOD, Susanne
CPC分类号： C12N9/20 , B01D15/327 , B01D15/363
摘要： The invention relates to a process for recovering and purifying bile salt-stimulated lipase (BSSL) in a solution which contains impurities, said process comprising the steps: (i) applying BSSL to a hydrophobic interaction chromatography (HIC) resin; (ii)removing impurities by washing said HIC resin with a wash composition having a pH in the range from 4 to 5; and (iii) recovering BSSL from said HIC resin.
-
公开(公告)号：EP1513831B1
公开(公告)日：2010-01-06
申请号：EP03760997.1
申请日：2003-06-18
申请人： Biovitrum AB (publ)
IPC分类号： C07D401/14 , C07D401/12 , C07D401/04 , C07D401/08 , C07D403/04 , C07D403/14 , C07D241/12 , C07D241/20 , A61K31/444 , A61K31/497 , A61P25/00
CPC分类号： C07D401/12 , C07D401/14
摘要： The invention relates to compounds of the general Formula (I). The compounds may be prepared by per se conventional methods and can be used for treating a human or animal subject suffering from a serotonin-related disorder. The invention also relates to such use as well as to pharmaceutical compositions comprising a compound of Formula (I).
-
19.发明授权USE OF SULFONAMIDE DERIVATIVES IN THE TREATMENT OF OBESITY OR FOR THE REDUCTION OF FOOD INTAKE 有权磺酰胺衍生物在肥胖或以减少营养治疗中的应用
公开(公告)号：EP1450806B1
公开(公告)日：2009-04-29
申请号：EP02783922.4
申请日：2002-11-06
申请人： Biovitrum AB (publ)
发明人： CALDIROLA, Patrizia
IPC分类号： A61K31/496 , A61P3/04
CPC分类号： A61K31/18 , A61K31/496
摘要： The invention provides a method of treatment or prophylaxis of obesity or for the reduction of food intake, comprising administering to a patient in need of such treatment a therapeutically effective amount of a sulfonamide compound of formula (I). Wherein the substituents are described in the specification.
-
20.发明公开Compounds useful for the treatment of obesity, type II diabetes and CNS disorders 审中-公开用于治疗肥胖症，II型糖尿病和CNS障碍的合适化合物
公开(公告)号：EP1897881A2
公开(公告)日：2008-03-12
申请号：EP07122274.9
申请日：2003-06-19
申请人： Biovitrum AB (publ)
IPC分类号： C07D471/04 , C07D495/04 , A61P3/00 , A61K31/4365
CPC分类号： C07D471/04 , C07D495/04
摘要： The present invention relates to compounds of the general formula (I),
wherein P is sulfone or sulfonamide; and
A, B, W, X, Y and R 3 are as defined in the description;
to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes, and/or CNS disorders, to achieve reduction of body weight and of body weight gain.
-
-
-
-
-
-
-
-
-
搜索结果
59 条记录 (耗时 0.025 秒)
