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21 条记录 (耗时 0.011 秒)

    Method of detecting biochemical substances and sensor for use in said method
    11.
    发明公开
    Method of detecting biochemical substances and sensor for use in said method 失效
    一种用于检测的生物化学物质和适当的传感器的方法。

    公开(公告)号：EP0589600A2

    公开(公告)日：1994-03-30

    申请号：EP93307198.7

    申请日：1993-09-13

    申请人： SOGO PHARMACEUTICAL COMPANY LIMITED

    发明人： Okahata, Yoshio ,  Toshinori, Sato ,  Kuniharu, Ijiro, No. 503, Kahsa Saginumamm

    IPC分类号： C12Q1/68 ,  G01N5/00

    CPC分类号： C12Q1/6825 ,  G01N29/036 ,  G01N2291/0255

    摘要： A method of detecting biochemical substances which method comprises chemically binding and immobilizing a probe DNA having a sequence complementary with a sequence specific to a DNA of a biochemical substance onto an electrode of a frequency conversion element, hybridizing the probe DNA with a sample to detect said DNA as a target DNA having a sequence specific to the probe DNA, and measuring frequency changes corresponding to mass changes due to hybridization to detect and identify a hybridized DNA; and a sensor use in the above method.

    摘要翻译： 用样品以检测所述检测生化物质，该方法包括在化学上结合和固定具有的频率转换元件的电极的特定的生物化学物质的DNA序列走上探针互补的序列的DNA，杂交的探针DNA的方法 DNA为具有特定的DNA样本的序列，以及测量频率的变化对应于由于杂交的质量变化，以检测并识别一个杂交的DNA的目标DNA; 并且在上述方法中的传感器使用。

    A method of determining the amount of the substances or ions contained in an ionic solution or a non-deionized solution and a crystal oscillator used therefor
    13.
    发明公开
    A method of determining the amount of the substances or ions contained in an ionic solution or a non-deionized solution and a crystal oscillator used therefor 失效
    步骤，用于确定在离子溶液中或在溶液nichtentionisierten和晶体振荡器用于此目的的物质的量。

    公开(公告)号：EP0359473A2

    公开(公告)日：1990-03-21

    申请号：EP89309071.2

    申请日：1989-09-07

    申请人： SOGO PHARMACEUTICAL COMPANY LIMITED

    发明人： Okahata, Yoshio

    IPC分类号： G01N27/00

    CPC分类号： G01N29/036 ,  G01N33/84 ,  G01N2291/0256

    摘要： Disclosed are a method of determining the amount of the substances or ions contained in an ionic solution or a non-deionized solution by measuring the frequency of a one side barrier-covered crystal oscillator comprising a crystal oscillator 1,2a,2b, a barrier 6 to cover over one of the electrodes 2b of the crystal oscillator through a predetermined insulative space 5 so as to prevent the ionic solution or the non-deionized solution from permeating therethrough and an adsorption film 7 cast on the other electrode 2a of the crystal oscillator, in situ in the state that the one side barrier-covered crystal oscillator is dipped in the ionic solution or the non-deionized solution, and the one side barrier-­covered crystal oscillator used therefor.

    摘要翻译： 公开的是物质或离子的量在离子溶液或通过测量一个侧屏障覆盖的晶体振荡器的频率，包括一个晶体振荡器1,2A，2B的非去离子溶液，屏障6包含在确定性采矿的方法 通过预定的绝缘空间5在晶体振荡器的电极2b的一个覆盖，以便防止从通过渗透有离子溶液或所述非去离子溶液和在晶体振荡器的另一个电极2A吸附膜-7铸， 原位的状态下做的一个侧屏障覆盖的晶体振荡器浸渍在离子溶液或所述非去离子溶液，为此所用的一个侧屏障覆盖的晶体振荡器。

    Pyrroloquinoline quinones as enzyme inhibitors
    16.
    发明公开
    Pyrroloquinoline quinones as enzyme inhibitors 失效
    吡咯烷醇喹啉作为酶抑制剂

    公开(公告)号：EP0262345A3

    公开(公告)日：1990-09-12

    申请号：EP87111397.3

    申请日：1987-08-06

    申请人： Sogo Pharmaceutical Company Limited

    发明人： Narutomi, Yuji ,  Katsumata, Manabu ,  Osawa, Yasuko ,  Uchikuga, Saburo

    IPC分类号： A61K31/475

    CPC分类号： A61K31/475

    摘要： The present invention concerns an enzyme inhibitor containing the compound represented by the following formula (I) as an effective ingredient :
    where R represents hydrogen or substituted or not substi­tuted alkyl group, alkenyl group, aryl group or aralkyl group, X represents ORʹ or NRʺR‴, in which Rʹ, Rʺ and R‴ represent respectively hydrogen or substituted or not substituted alkyl group, alkenyl group, aryl group or aralkyl group. The enzyme inhibitor according to the present inven­tion can effectively inhibit aldose reductase, glyoxalase I and reverse transcriptase.

    摘要翻译： 本发明涉及含有下式（I）表示的化合物作为有效成分的酶抑制剂：其中R表示氢或取代或未取代的烷基，烯基，芳基或芳烷基，X表示OR '或NR''R“'，其中R'，R”和R“”分别代表氢或被取代或未取代的烷基，烯基，芳基或芳烷基。 根据本发明的酶抑制剂可以有效抑制醛糖还原酶，乙二醛酶I和逆转录酶。

    Skin anti-ageing composition
    20.
    发明公开
    Skin anti-ageing composition 失效
    Hautalterungsschutzmittel

    公开(公告)号：EP0688559A1

    公开(公告)日：1995-12-27

    申请号：EP95114397.3

    申请日：1995-09-13

    申请人： SHISEIDO COMPANY LIMITED ,  Sogo Pharmaceutical Company Limited

    发明人： Tominaga, Naoki, c/o The Shiseido Research Ctr.

    IPC分类号： A61K7/48

    CPC分类号： A61K8/466 ,  A61K8/35 ,  A61Q17/04 ,  A61Q19/08 ,  Y10S514/844 ,  Y10S514/846

    摘要： An anti-aging preparation for cutaneous application which prevents cutaneous aging, a collagen cross-linking inhibitory preparation for cutaneous application which inhibits collagen cross-linking occurring predominantly in the dermis to maintain skin elasticity and to prevent wrinkles or sagging, and an anti-UV preparation for cutaneous application which protects the skin from bad influences of excessive ultraviolet rays of sunlight are disclosed. The preparations contain one or two of aminoethyl compounds represented by formula (I):

            NH₂CH₂CH₂X   (I)


    wherein X represents -SO₂H or -SO₂SH,
    and preferably containing at least one ultraviolet protective agent.

    摘要翻译： 用于皮肤应用的抗衰老制剂，其防止皮肤老化，用于皮肤应用的胶原交联抑制剂，其抑制主要在真皮中发生的胶原交联以保持皮肤弹性并防止皱纹或下垂，以及抗紫外线 公开了皮肤应用的准备，其保护皮肤免受太阳紫外线过多的不良影响。 制剂含有一种或两种式（I）表示的氨基乙基化合物：其中X表示-SO 2 H或-SO 2 SH的NH 2 CH 2 CH 2 X（I），优选含有至少一种紫外线防护剂。