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    USE OF CARBOXYMETHYL CELLULOSE ACETATE BUTYRATE
    12.
    发明公开
    USE OF CARBOXYMETHYL CELLULOSE ACETATE BUTYRATE 审中-公开
    VERWENDUNG VON羧甲基羊毛脂肪酸乙酯

    公开(公告)号：EP1332160A4

    公开(公告)日：2006-11-29

    申请号：EP01992724

    申请日：2001-11-01

    申请人： EASTMAN CHEM CO

    发明人： OBIE RONALD

    IPC分类号： B05D5/00 ,  B05D7/00 ,  B05D7/10 ,  B05D7/24 ,  B27N7/00 ,  B32B21/04 ,  C08B11/20 ,  C08B13/00 ,  C08L1/32 ,  C09D101/32 ,  C09J101/32 ,  D06M13/224 ,  D06M15/07 ,  D21H17/27 ,  D21H19/34 ,  D21H21/16 ,  C08L1/00

    CPC分类号： D21H17/27 ,  B05D7/10 ,  B05D7/52 ,  B27N7/005 ,  C08B11/20 ,  C08B13/00 ,  C08L1/32 ,  C09D101/32 ,  C09J101/32

    摘要： A method for improving holdout on a coated, cellulosic substrate, such as a man-made fiber board. The process comprises the steps of applying an aqueous carboxymethyl cellulose acetate butyrate size composition to a man-made fiber substrate, forming a sized substrate. The sized substrate is then dried. Next, an aqueous coating composition is applied to form a coated, sized substrate. The coated, size substrate is then dried. According to the invention, the aqueous carboxymethyl cellulose acetate butyrate size composition used in the process comprises carboxymethyl cellulose acetate butyrate, water, and an organic solvent. The invention also relates to a sized, man-made fiber substrate comprising a man-made fiber substrate and a carboxymethyl cellulose acetate butyrate size. The carboxymethyl cellulose acetate butyrate may be either an internal sizing agent, or an an external sizing agent.

    摘要翻译： 一种用于改进涂覆的纤维素基材如人造纤维板上的保持力的方法。 该方法包括将羧甲基纤维素乙酸丁酸酯水溶液施用到人造纤维基材上，形成施胶的基材的步骤。 然后干燥尺寸化的基材。 接下来，施涂含水涂料组合物以形成涂布尺寸的基材。 然后干燥涂布的尺寸基材。 根据本发明，该方法中使用的羧甲基纤维素醋酸丁酸酯水性组合物包含羧甲基纤维素乙酸丁酸酯，水和有机溶剂。 本发明还涉及包含人造纤维基质和羧甲基纤维素乙酸丁酸酯大小的尺寸化的人造纤维基质。 羧甲基纤维素乙酸丁酸酯可以是内部上浆剂，也可以是外部上浆剂。

    EFFICIENT PROCESS FOR PREPARING AN ESTER OF A CELLULOSE ETHER
    15.
    发明授权
    EFFICIENT PROCESS FOR PREPARING AN ESTER OF A CELLULOSE ETHER 有权

    公开(公告)号：EP3212675B1

    公开(公告)日：2018-08-22

    申请号：EP15791421.9

    申请日：2015-10-21

    申请人： Dow Global Technologies Llc

    发明人： PETERMANN, Oliver ,  SPREHE, Matthias ,  APPELL, Robert B.

    IPC分类号： C08B13/00 ,  C08L1/32 ,  A61K47/38 ,  C09D101/32

    CPC分类号： C08B13/00 ,  C08L1/32 ,  C09D101/32

    摘要： A process for producing an esterified cellulose ether can be efficiently be produced by reacting a moist cellulose ether having a water content of at least 10 percent, based on the weight of the moist cellulose ether, with an aliphatic monocarboxylic acid anhydride, a dicarboxylic acid anhydride or a combination thereof. Further improvements in efficiency and reduction in process steps are achieved in a process for producing an esterified cellulose ether which comprises the steps of a) reacting cellulose with an alkaline material to produce alkali cellulose, b) reacting the produced alkali cellulose with one or more etherifying agents and washing the produced cellulose ether to obtain a moist cellulose ether having a water content of at least 10 weight percent, and c) reacting the moist cellulose ether with an aliphatic monocarboxylic acid anhydride and/or a dicarboxylic acid anhydride and with a depolymerizing agent.

    HYDROXYALKYL ALKYL CELLULOSE, METHOD FOR PRODUCING THE SAME, AND SOLID PREPARATION
    17.
    发明公开
    HYDROXYALKYL ALKYL CELLULOSE, METHOD FOR PRODUCING THE SAME, AND SOLID PREPARATION 审中-公开
    羟烷基烷基纤维素，其制备方法和固体制剂

    公开(公告)号：EP3309179A1

    公开(公告)日：2018-04-18

    申请号：EP17195310.2

    申请日：2017-10-06

    申请人： Shin-Etsu Chemical Co., Ltd.

    发明人： YOKOSAWA, Takuya ,  KITAGUCHI, Taishi ,  HIRAMA, Yasuyuki ,  KITAMURA, Akira

    IPC分类号： C08B11/193

    CPC分类号： C08B3/08 ,  A61K9/146 ,  A61K9/2054 ,  A61K47/38 ,  C08B3/14 ,  C08B11/193 ,  C08L1/32 ,  C09D101/30 ,  G01N15/0211 ,  G01N2021/479

    摘要： There is provided is a hydroxyalkyl alkyl cellulose exhibiting good flowability and high compressibility. More specifically, provided are a hydroxyalkyl alkyl cellulose having a volume-based average particle diameter, determined by dry laser diffractometry, of 50 to 100 µm, and having, on a basis of a dynamic image analysis to divide all particles into fine particles, spherical particles and fibrous particles, a volume fraction of the fibrous particles consisting of long and short fibrous particles relative to all of the particles of 45 to 70%, and a volume fraction of the fine particles relative to all of the particles of less than 2.0%; a solid preparation including the hydroxyalkyl alkyl cellulose; and others.

    摘要翻译： 提供了显示良好流动性和高可压缩性的羟烷基烷基纤维素。 更具体而言，提供通过干式激光衍射法测定的体积基准平均粒径为50〜100μm的羟烷基烷基纤维素，并且基于动态图像分析将全部颗粒分成细颗粒，球形 颗粒和纤维状颗粒，由相对于所有颗粒的长和短纤维颗粒组成的纤维状颗粒的体积分数为45-70％，并且细颗粒相对于所有颗粒的体积分数小于2.0％ ; 包含羟烷基烷基纤维素的固体制剂; 和别的。

    LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE, PRODUCTION METHOD THEREOF, AND SOLID PREPARATION
    18.
    发明公开
    LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE, PRODUCTION METHOD THEREOF, AND SOLID PREPARATION 审中-公开
    低取代羟丙基纤维素及其生产方法和固体制剂

    公开(公告)号：EP3308776A1

    公开(公告)日：2018-04-18

    申请号：EP17195313.6

    申请日：2017-10-06

    申请人： Shin-Etsu Chemical Co., Ltd.

    发明人： HIRAMA, Yasuyuki

    IPC分类号： A61K9/20 ,  C08B11/193

    CPC分类号： C08B11/08 ,  A61K9/146 ,  A61K9/2054 ,  A61K9/2095 ,  A61K31/167 ,  A61K47/38 ,  C08B11/193 ,  C08B11/20 ,  C08L1/32 ,  C09D101/30

    摘要： There are provided low-substituted hydroxypropyl cellulose (L-HPC) having good compressibility and capping-prevention performance, and others. Specifically, provided are L-HPC having a hydroxypropoxy content of 5 to 16% by weight, a volume fraction of long fibrous particles of 20 to 40% and a volume fraction of short fibrous particles of 26 to 60% with the proviso that the latter is greater than the former; and a solid preparation containing the L-HPC. Also provided is a method for producing the L-HPC including the steps of: bringing powdery pulp having a length-weighted mean width of 10 to 25 µm into contact with an alkali metal hydroxide solution, reacting the alkali cellulose with propylene oxide, and neutralizing the alkali metal hydroxide present in the reaction product with an acid to precipitate crude low-substituted hydroxypropyl cellulose in the absence of a step of dissolving a portion or all of the reaction product.

    摘要翻译： 提供了具有良好的压缩性和防盖性能的低取代羟丙基纤维素（L-HPC）等。 具体而言，提供具有5至16重量％的羟丙氧基含量，20至40％的长纤维颗粒的体积分数和26至60％的短纤维颗粒的体积分数的L-HPC，条件是后者 大于前者; 和含有L-HPC的固体制剂。 还提供了生产L-HPC的方法，包括以下步骤：使长度加权平均宽度为10-25μm的粉末状纸浆与碱金属氢氧化物溶液接触，使碱性纤维素与环氧丙烷反应，并中和 存在于反应产物中的碱金属氢氧化物与酸在不溶解部分或全部反应产物的步骤不存在的情况下沉淀粗制低取代羟丙基纤维素。

    COMPOSITION FOR HEAT MELT EXTRUSION AND METHOD FOR PRODUCING HEAT MELT EXTRUDED PRODUCT USING SAME
    19.
    发明公开
    COMPOSITION FOR HEAT MELT EXTRUSION AND METHOD FOR PRODUCING HEAT MELT EXTRUDED PRODUCT USING SAME 有权
    组成的挤出和熔化过程用于生产SCHMELZEXTRUDIERTEM产品，

    公开(公告)号：EP3006049A4

    公开(公告)日：2017-02-22

    申请号：EP14806945

    申请日：2014-06-03

    申请人： SHIN-ETSU CHEMICAL CO LTD

    发明人： WARASHINA SHOGO ,  KUSAKI FUMIE ,  KIKUCHI KAZUKI ,  OBARA SAKAE ,  MARUYAMA NAOSUKE

    IPC分类号： A61K47/38 ,  A61K9/20 ,  C08B11/08

    CPC分类号： A61K47/38 ,  A61K9/146 ,  A61K31/4422 ,  A61K31/496 ,  C08B11/193 ,  C08B11/20 ,  C08B13/00 ,  C08J3/201 ,  C08J2301/32 ,  C08L1/32

    摘要： Provided are a composition for hot-melt extrusion which can be hot-melt extruded at a temperature lower than a conventional temperature and therefore free of heat-induced deactivation of a drug; and a method for producing a hot-melt extrusion product which is simpler than a spray-drying method. More specifically, provided is a composition for hot-melt extrusion comprising a drug and hypromellose acetate succinate (HPMCAS) having a hydroxypropoxy molar substitution of 0.40 or more. Also provided is a method for producing a hot-melt extrusion product comprising a step of hot-melt extruding a composition for hot-melt extrusion comprising a drug and hypromellose acetate succinate having a hydroxypropoxy molar substitution of 0.40 or more at a hot-melt temperature of melting temperature of the hypromellose acetate succinate or higher, or at a hot-melt temperature equal to or higher than a temperature at which both the hypromellose acetate succinate and the drug become melted.

    摘要翻译： 提供的是用于热熔挤出哪个可以是热熔在比常规温度低，因此游离药物的热诱导失活的温度下挤出的组合物; 和用于生产热熔挤出产品中的所有比喷雾干燥方法更简单的方法。 更具体地，提供了一种用于热熔融挤出含有药物和羟丙基甲基纤维素乙酸琥珀酸酯（HPMCAS），其具有的羟基丙氧基○时40或更大的摩尔取代度的组合物。 这样提供了一种用于生产热熔挤出产品，其包括热熔挤出用于热熔融挤出，其包括具有热熔融温度的0:40或更高的羟基丙氧基摩尔取代的药物和羟丙基甲基纤维素乙酸琥珀酸酯的组合物的步骤的方法 羟丙甲纤维素乙酸酯琥珀酸酯或更高的熔融温度的，或在热熔温度比在其中两个羟丙甲纤维素醋酸琥珀酸酯和药物成为熔融的温度等于或更高。