公开(公告)号：EP1514923A4

公开(公告)日：2005-12-21

申请号：EP03733522

申请日：2003-06-20

申请人： TAKARA BIO INC

发明人： SAKAI TAKESHI ,  ISHIZUKA KUMIKO ,  KATO IKUNOSHIN

IPC分类号： C12N9/16 ,  C12N9/24 ,  C12N9/88 ,  C12N15/12 ,  C12P11/00 ,  C12P19/04 ,  C12N9/44 ,  C08B37/00

CPC分类号： C12P19/04 ,  C12N9/16 ,  C12N9/2402 ,  C12N9/88 ,  C12P11/00 ,  C12Y302/01044 ,  C12Y302/01051

摘要： Sulfated fucan lyase capable of decomposing sulfated fucan derived from sea cucumber; a process for producing the enzyme; a low molecular compound obtained by causing the enzyme to act on sulfated fucan; a process for producing the same; and an activating factor for sulfated fucan lyase.

公开(公告)号：EP0919237A1

公开(公告)日：1999-06-02

申请号：EP97900470.2

申请日：1997-01-21

申请人： TAKARA SHUZO CO. LTD. ,  Research Institute for Glycotechnology

发明人： SAKAI, Takeshi, Research Inst. Glycotechnology ,  KITANO, Hideo, Research Inst. Glycotechnology ,  YU, Fu-gong, Research Inst. Glycotechnology ,  NAKAYAMA, Shinji, Research Inst. Glycotechnology ,  KOJIMA, Kaoru, Research Inst. Glycotechnology ,  KIMURA, Hitomi, Research Inst. Glycotechnology ,  NAKANISHI, Yoshikuni, ResearchInst.Glycotechnology ,  KATAYAMA, Kaoru, Research Inst. Glycotechnology ,  TOMINAGA, Takanari, Takara Shuzo Co., Ltd. ,  SHIMANAKA, Kazuo, Takara Shuzo Co., Ltd. ,  IKAI, Katsushige, Takara Shuzo Co., Ltd. ,  KATO, Ikunoshin, Research Inst. Glycotechnology

IPC分类号： A61K31/725 ,  C08B37/00

CPC分类号： C12Y302/01078 ,  A61K31/737 ,  C12N9/2494 ,  C12P19/14 ,  C12Y302/01044

摘要： Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.

摘要翻译： 包含含有硫酸化岩藻糖的多糖和/或其降解产物的细胞凋亡诱导剂，抗癌药和制癌药以及通过使用含有硫酸化岩藻糖的多糖和/或降解产物诱导凋亡的方法 （一种或多种）作为活性成分。 一种降解酶，用于生产含硫酸化岩藻糖的多糖的降解产物。

公开(公告)号：EP0870771A1

公开(公告)日：1998-10-14

申请号：EP96910215.1

申请日：1996-04-22

申请人： TAKARA SHUZO CO. LTD. ,  Research Institute for Glycotechnology

发明人： SAKAI, Takeshi, Res. Inst. for Glycotechnology ,  KIMURA, Hitomi, Res. Inst. for Glycotechnology ,  KOJIMA, Kaoru, Res. Inst. for Glycotechnology ,  IKAI, Katsushige, Takara Shuzo Co., Ltd. ,  AKIYOSHI, Sumiko, Takara Shuzo Co., Ltd. ,  NAKANISHI, Yoshikuni, Res.Inst.for Glycotechnology ,  KATO, Ikunoshin, Res. Inst. for Glycotechnology

IPC分类号： C07H11/00 ,  C12N9/24 ,  C12N1/20 ,  C12P19/14

CPC分类号： C12Y302/01044 ,  C07H1/00 ,  C07H3/06 ,  C07H5/10 ,  C12N9/2402 ,  C12N9/88 ,  C12P19/44 ,  C12R1/01 ,  Y10S435/822

摘要： A novel endo-fucoidan-lyase and a novel microorganism useful in the production of sugar compounds.
Sugar compounds represented by the following general formula (1), wherein at least one of alcoholic hydroxyl group has been sulfated, or salts thereof:


wherein Y represents hydrogen or a group represented by the following formula (2).