摘要:
An improved process for the preparation of 2-arylvinyl alkyl ether compounds of structural formula (I). In addition, the present invention provides an improved process for the preparation of 1,4-diaryl-2-fluoro-2-butene compounds of structural formula (V).
摘要:
A preferred process for producing a brominated, non-fused aromatic composition involves a continuous bromination in a continuous, mixed reactor such as a continuous stirred tank reactor. Bromine and the aromatic substrate, and optionaly a bromination catalyst, are continuously fed to a reaction zone to form a reaction mixture, and the reaction mixture is continuously withdrawn from the reaction zone after an established average residence time. Bromination levels can be readily controlled by controlling the average residence time of the reaction mixture within the reaction zone. Preferred continuous processes also provide mixed, brominated compositions having product distributions which are substantially broader than that obtained by batch brominations conducted to achieve the same level of bromination. Preferred products thus have broad melting ranges which are advantageous in compounding operations.
摘要:
There is disclosed a dihalopropene compound of the formula I:
wherein l is an integer of 1 to 5; m is an integer of 1 to 4; R¹'s and R²'s are the same or different and are independently halogen or various other groups; D is oxygen, NH or sulfur, X's are the same or different and are independently chlorine or bromine; Y is oxygen or various other groups, Z, P and Q are the same or different and are independently nitrogen or CH, provided that P and Q are not simultaneously nitrogen, and when Y is sulfur, Z is CH. Also disclosed is an insecticide/acaricide comprising the dihalopropene compound as an active ingredient. The dihalopropene compound exhibits excellent insecticidal/acaricidal action. Further disclosed is an intermediate compound for use in the production of the dihalopropene compound.
摘要:
Methods of producing carboxylic acid ester derivatives of formulae (I) and (II), which are useful, for instance, as intermediates for producing an anti-hypercholesterolemic agent having an inhibitory effect on HMG-CoA Reductase: wherein R 1 and R 2 are independently a protective group for hydroxyl group, or R 1 and R 2 integrally constitute a protective group for hydroxyl groups; R 3 is an alkyl group, or an aryl group; and R 4 is a substituted aryl group, a substituted heterocyclic group, a substituted vinyl group, or a substituted cycloalkenyl group; and wherein R 1 , R 2 , R 3 and R 4 are respectively the same as defined in the above formula (I), are disclosed. In addition, intermediates for use in these methods of producing the carboxylic acid ester derivatives are disclosed.
摘要翻译:制备式(I)和(II)的羧酸酯衍生物的方法,其可用于例如具有对HMG-CoA还原酶具有抑制作用的抗高胆固醇药物的中间体:其中R 1 >和R 2独立地是羟基的保护基,或R 1和R 2一体地构成羟基的保护基; R 3是烷基或芳基; R 4是取代的芳基,取代的杂环基,取代的乙烯基或取代的环烯基; 和其中R 1,R 2,R 3和R 4分别与上述式(I)中所定义的基团相同的。 此外,公开了用于制备羧酸酯衍生物的这些方法中的中间体。
摘要:
The present invention relates to aldehyde compounds represented by the general formula (I)
wherein R₁ and R₂, which may be identical or different, represent a hydrogen or halogen atom or a C₁₋₅ alkyl, C₁₋₅-haloalkyl, C₁₋₅-alkoxyl, C₁₋₅-haloalkoxyl, C₂₋₅-alkenyl or C₂₋₅-alkenyloxyl group, or represent, taken together, a methylenedioxy, C₃₋₄-alkylene, ethyleneoxy or C₁₋₅-alkylethyleneoxy group with the proviso that when R₁ and R₂ are identical they are not hydrogen atoms. These compounds are valuable intermediates for the production of insecticidal and/or acaricidal ether compounds.