AMORPHOUS PAROXETINE COMPOSITON
    23.
    发明公开
    AMORPHOUS PAROXETINE COMPOSITON 审中-公开
    非晶态PAROXETINE COMPOSITON

    公开(公告)号:EP1248619A1

    公开(公告)日:2002-10-16

    申请号:EP00982065.5

    申请日:2000-10-27

    IPC分类号: A61K31/445 C07D405/12

    摘要: A stable amorphous paroxetine hydrochloride composition suitable as atherapeutic agent is prepared employing an aqueous solvent medium containing an acidulant and polyvinylpyrrolidone and drying the resulting solid dispersion. The preferred compositions include amorphous paroxetine hydrochloride, polyvinylpyrrolidone and citric acid.

    摘要翻译: 适合作为治疗剂的稳定的无定形帕罗西汀盐酸盐组合物使用含有酸化剂和聚乙烯吡咯烷酮的水性溶剂介质并干燥所得固体分散体来制备。 优选的组合物包括无定形帕罗西汀盐酸盐,聚乙烯吡咯烷酮和柠檬酸。

    REGIMEN AND KIT FOR AMELIORATION OF PREMATURE EJACULATION
    30.
    发明公开
    REGIMEN AND KIT FOR AMELIORATION OF PREMATURE EJACULATION 审中-公开
    治疗早泄和相关套件

    公开(公告)号:EP1180021A1

    公开(公告)日:2002-02-20

    申请号:EP00932038.3

    申请日:2000-05-03

    IPC分类号: A61K9/20

    CPC分类号: A61K31/4525

    摘要: Male patient suffering from premature ejaculation dysfunction are treated by an oral therapy regimen of administration of paroxetine substantially within several hours before sexual intercourse. The beneficial effect of the paroxetine treatment can be optimized and maintained by a combination oral therapy regimen in which the patient converts to continual maintenance paroxetine administration after an initial loading period of daily doses of paroxetine taken over of relatively short duration.