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公开(公告)号：EP3618925A1
公开(公告)日：2020-03-11
申请号：EP18725129.3
申请日：2018-05-03
发明人： VIK, Torbjørn , HEESE, Harald Sepp , NEUKIRCHEN, Christoph , ISOLA, Alfonso Agatino , WEESE, Rolf Jürgen
IPC分类号： A61N5/10
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公开(公告)号：EP3612272A1
公开(公告)日：2020-02-26
申请号：EP18717631.8
申请日：2018-04-20
发明人： WEESE, Rolf Jürgen , RENISCH, Steffen , HEESE, Harald Sepp , VIK, Torbjørn , ISOLA, Alfonso Agatino , NEUKIRCHEN, Christoph
IPC分类号： A61N5/10
摘要： The invention relates to the planning of a radiation therapy treatment of at least one structure in a region of a patient body. A planning unit obtains a first treatment plan generated on the basis of a planning image of the body region and on the basis of dose objectives. Moreover, the planning unit receives a further image of the body region of the patient body, determines a transformation for generating an adapted treatment plan from the first treatment plan and/or for generating an adapted dose distribution from the dose distribution corresponding to the first treatment plan on the basis of the further image and determines an adapted treatment plan on the basis of the transformation and/or the adapted dose distribution. In accordance with the invention, the transformation on the basis of the dose objectives
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公开(公告)号：EP3546021A1
公开(公告)日：2019-10-02
申请号：EP18164832.0
申请日：2018-03-29
发明人： HEESE, Harald Sepp , VIK, Torbjoern , WEESE, Rolf Jürgen , ISOLA, Alfonso Agatino , NEUKIRCHEN, Christoph , BAL, Matthieu Frédéric
摘要： The invention relates to a planning system 7 for planning a radiation therapy procedure, wherein the radiation therapy procedure includes rotating a radiation source 2, which is configured to emit a radiation beam 3 for treating a subject 4, along an arc around the subject, in order to apply the radiation beam to the subject in different treatment directions. A sequence of sub-arcs groups is provided, wherein a respective sub-arcs group comprises several sub-arcs of the arc, which are evenly distributed along the arc, wherein a treatment plan is generated by sequentially determining for each sub-arcs group treatment parameters, which define a property of the radiation beam, in the provided sequence. Determining the treatment parameters by using this sequence leads to an increased likelihood that really an optimal treatment plan is generated.
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24.发明公开
公开(公告)号：EP3498335A1
公开(公告)日：2019-06-19
申请号：EP17306794.3
申请日：2017-12-18
发明人： WEESE, Rolf Jürgen , RENISCH, Steffen , DESHPANDE, Hrishikesh Narayanrao , SCHULZ, Heinrich , KABUS, Sven , ALLAIRE, Stéphane , ISOLA, Alfonso Agatino , NEUKIRCHEN, Christoph , BONDAR, Luiza , WIEGERT, Jens
IPC分类号： A61N5/10
摘要： The invention relates to a system for assisting in evaluating a contour of an anatomic structure (22) with respect to a dose distribution corresponding to a treatment plan for a radiation therapy treatment of a patient. The system comprises an evaluation unit particularly configured to evaluate the dose distribution in varying distances from the contour of the anatomic structure (22) to determine at least one point where the evaluated dose distribution fulfills a predetermined condition, and to determine the distance between the at least one point and the contour and/or to visualize the at least one point to a user of the system.
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公开(公告)号：EP3427796A1
公开(公告)日：2019-01-16
申请号：EP18188228.3
申请日：2015-09-09
发明人： VIK, Torbjoern , HEESE, Harald Sepp , BYSTROV, Daniel , WEESE, Juergen , NEUKIRCHEN, Christoph , ISOLA, Alfonso Agatino , BAL, Matthieu Frederic
IPC分类号： A61N5/10
摘要： A radiation planning system includes a predictor-corrector optimizer unit which computes a predicted dose based on a collection of control points with a current approximate dose, each control point with a corresponding set of leaf positions, and determines an additional control point with a corresponding set of leaf positions based on a difference of the predicted fluence and the current approximate fluence through a least cost or shortest path in a layered graph structure of realizable leaf positions. Tools are described to help a planner to evaluate the effect of parameter changes to the current plan based on an identified zone of influence. The planner interactively views the current plan based on a visualization of the plan objectives and correlations between the objectives.
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公开(公告)号：EP3160586B1
公开(公告)日：2018-10-10
申请号：EP15732217.3
申请日：2015-06-25
CPC分类号： A61N5/1031 , A61N5/103 , A61N5/1048 , A61N2005/1032 , A61N2005/1074 , G06F19/00 , G06F19/325 , G06F19/34 , G06F19/3481 , G06N3/12
摘要： The present invention relates to a radiotherapy planning system (100) for determining a solution (101) corresponding to a fluence profile. The invention proposes to use a Pareto frontier navigator (140) to select the best plan from a set of various auto-planned solutions. An interactive graphical user interface (400) is provided to the planner to navigate among convex combinations of auto-planned solutions. This proposed Pareto plan navigation can be considered as a further optional refinement process, which can be applied to find the best plan in those cases where auto-generated solutions are not fully satisfying the planner's requirements. The navigation tool (400) moves locally through a set of auto-generated plans and can potentially simplify the planner's decision making process and reduce the whole planning time on complex clinical cases from several hours to minutes.
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公开(公告)号：EP3319691A1
公开(公告)日：2018-05-16
申请号：EP16734688.1
申请日：2016-07-06
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61N5/1037 , A61N5/1049 , A61N2005/105 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061
摘要： The invention relates to a system for delivering a radiation treatment to a structure (21) within a body. In the system, a plurality of treatments plans is provided, each treatment plan being associated to one of a plurality of predefined possible position (33a; 33b) of the structure (21), which area regularly distributed on at least one predefined surface (32a; 32b). A control unit is configured to determine the position of the structure during the treatment and to select a treatment plan which is associated with a predefined possible position having a smallest distance to the determined position, for controlling the radiation source in response to the detection of the position. Moreover, the invention relates to a computer program for controlling the system and to a planning unit for generating the treatment plans.
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公开(公告)号：EP3197553B1
公开(公告)日：2018-03-21
申请号：EP15774984.7
申请日：2015-09-09
发明人： VIK, Torbjoern , HEESE, Harald Sepp , BYSTROV, Daniel , WEESE, Juergen , NEUKIRCHEN, Christoph , ISOLA, Alfonso Agatino , BAL, Matthieu Frederic
IPC分类号： A61N5/10
CPC分类号： A61N5/1036 , A61N5/103 , A61N5/1031 , A61N5/1039 , A61N5/1045 , G06F19/3456 , G16H50/30
摘要： A radiation planning system includes a predictor-corrector optimizer unit which computes a predicted dose based on a collection of control points with a current approximate dose, each control point with a corresponding set of leaf positions, and determines an additional control point with a corresponding set of leaf positions based on a difference of the predicted fluence and the current approximate fluence through a least cost or shortest path in a layered graph structure of realizable leaf positions. Tools are described to help a planner to evaluate the effect of parameter changes to the current plan based on an identified zone of influence. The planner interactively views the current plan based on a visualization of the plan objectives and correlations between the objectives.
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29.发明公开DEVICE FOR DETERMINING ILLUMINATION DISTRIBUTIONS FOR IMRT 有权VORRICHTUNG ZUR BESTIMMUNG DER BELEUCHTUNGSVERTEILUNGFÜRIMRT
公开(公告)号：EP3003483A1
公开(公告)日：2016-04-13
申请号：EP14725093.0
申请日：2014-05-14
IPC分类号： A61N5/10
CPC分类号： A61N5/1036 , A61N5/1045 , A61N5/1047 , A61N2005/1074
摘要： The invention relates to a device for determining illumination distributions (18) for IMRT. A layered graph structure is used, which considers which extensions of an illumination distribution along a respective line and thus which illumination distributions are realizable, for determining extensions for the illumination distributions. Moreover, second weights defining fluences of the illumination distributions are determined such that a deviation between a provided fluence map and a fluence map formed by a combination of illumination distributions, which are defined by the respective determined extensions and the respective second weight, is minimized. This determination procedure leads to illumination distributions, which very well correspond to the provided fluence map and which are automatically realizable by the radiation device. This leads to an improved IMRT, wherein a post-processing of the determined illumination distributions for ensuring that the determined illumination distributions are really realizable is not necessarily required.
摘要翻译： 本发明涉及一种用于确定IMRT的照明分布（18）的装置。 使用分层图结构，其考虑沿着相应线的照明分布的哪些延伸，并且因此考虑哪些照明分布是可实现的，以确定用于照明分布的扩展。 此外，确定照明分布的通量的第二权重被确定为使得由所确定的扩展和相应的第二权重定义的由照明分布的组合形成的所提供的注量图与通量密度图之间的偏差最小化。 该确定程序导致照明分布，其非常对应于所提供的注量图并且可由辐射装置自动实现。 这导致改进的IMRT，其中对确定的确定的照明分布真正可实现的所确定的照明分布的后处理不一定是必需的。
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公开(公告)号：EP3892224A1
公开(公告)日：2021-10-13
申请号：EP20169170.6
申请日：2020-04-10
摘要： A processing device (1) and method for determining a position and/or orientation for a multi-hole grid template in a medical interventional procedure is disclosed. An anatomical spatial information processing unit (2) receives and/or processes data representative of a target spatial volume in the body, and a grid position sampler (4) generates candidate positions of the grid template. A quality calculator (5) calculates, for each candidate, a quality metric indicating the suitability of the candidate position of the grid template for the interventional procedure. A position selector (6) selects the position and/or orientation from the candidates based on the quality metric. For each candidate, an spatial relationship between each grid hole trajectory and the target volume is determined, and the quality metric takes, at least, this spatial relationship into account.
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