摘要:
A server computer and a multitude of client computers form a network computing system that is scalable and adapted to continue to evaluate the performance characteristics of a number of genes generated using a software application running on the client computers. Each client computer continues to periodically receive data associated with the genes stored in its memory. Using this data, the client computers evaluate the performance characteristic of their genes by comparing a solution provided by the gene with the periodically received data associated with that gene. Accordingly, the performance characteristic of each gene may be updated and varied with each periodically received data. The performance characteristic of a gene defines its fitness. The genes may be virtual asset traders that recommend trading options, and the data associated with the genes may be historical trading data.
摘要:
The present invention relates to a radiotherapy planning system (100) for determining a solution (101) corresponding to a fluence profile. The invention proposes to use a Pareto frontier navigator (140) to select the best plan from a set of various auto-planned solutions. An interactive graphical user interface (400) is provided to the planner to navigate among convex combinations of auto-planned solutions. This proposed Pareto plan navigation can be considered as a further optional refinement process, which can be applied to find the best plan in those cases where auto-generated solutions are not fully satisfying the planner's requirements. The navigation tool (400) moves locally through a set of auto-generated plans and can potentially simplify the planner's decision making process and reduce the whole planning time on complex clinical cases from several hours to minutes.
摘要:
A server computer and a multitude of client computers form a network computing system that is scalable and adapted to continue to evaluate the performance characteristics of a number of genes generated using a software application running on the client computers. Each client computer continues to periodically receive data associated with the genes stored in its memory. Using this data, the client computers evaluate the performance characteristic of their genes by comparing a solution provided by the gene with the periodically received data associated with that gene. Accordingly, the performance characteristic of each gene may be updated and varied with each periodically received data. The performance characteristic of a gene defines its fitness. The genes may be virtual asset traders that recommend trading options, and the data associated with the genes may be historical trading data.
摘要:
Provided are systems and methods for analyzing genetic sequence data from next generation sequence (NGS) platforms. Also provided are methods for the preparation of samples for nucleic acid sequence analysis by NGS. Variant calling is performed with a modified GATK variant caller. Mapping the reads to a genomic reference sequence is performed with a Burrows Wheeler Aligner (BWA) and does not comprise soft clipping. The genomic reference sequence is GRCh37.1 human genome reference. The sequencing method comprises emulsion PCR (emPCR), rolling circle amplification, or solid-phase amplification. In some embodiments, the solid-phase amplification is clonal bridge amplification.
摘要:
A method for the optimization of the design and / or operation of a computer system is disclosed. According to the invention the method constructs an initial set (40) of solutions as input to an iterative optimization procedure by evaluating a preliminary set (13) of solutions according to at least one selection criterion (14). From this evaluation, a first subset (17), which contains solutions which satisfy the at least one selection criterion (14) to a degree better than a predefined first threshold (23, 25), results. The method then identifies common features of the solutions in the first subset (17). From these common features deployment rules (19) are derived, which constrain the solutions selected for the initial set (40), and which optionally also constrain the modifications of solutions during the iterative procedure. The deployment rules (19) may be updated during the iterative procedure.
摘要:
According to an aspect of an embodiment, operations include receiving data comprising tabular datasets and code files. The operations further include generating a task specification corresponding to each dataset and determining data type information for features of each dataset. The operations further include extracting a plurality of API methods from the code files and generating an ML pipeline based on the data type information and the task specification. The operations further include obtaining variations of the ML pipeline based on options associated with at least one ML component and generating a database of pipelines based on the ML pipeline and the variations. The operations further include selecting candidate ML pipelines from the database based on an optimization approach and executing the candidate ML pipelines to evaluate a performance of each candidate pipeline on test data. The operations further include obtaining a training corpus of ML pipelines for pipeline recommendation.
摘要:
A method of tracking information flows through multiple network systems includes selecting a primary network system from a population of primary and secondary network systems, wherein each of the primary and secondary network systems include network nodes, selecting first selected characteristic features that identify network nodes of the primary network system that provide interaction between the selected primary network system and secondary network systems, identifying at least one secondary network system that is capable of interacting with the network nodes of the primary network system, subdividing the primary network into subnetwork systems based on identifying primary network nodes that provide interaction between the primary network system and secondary network nodes, identifying the subnetwork systems that are capable of interacting with one or more network nodes of the secondary network systems, identifying a subnetwork node count of the primary network nodes in each subnetwork, identifying objects that are capable of interacting with the primary network nodes, and determining a coincidence frequency or a coincidence measurement between features of objects interacting with the primary network nodes and the features of the primary network nodes that indicate information exchanges between the primary and secondary network nodes.
摘要:
The present invention relates to a radiotherapy planning system (100) for determining a solution (101) corresponding to a fluence profile. The invention proposes to use a Pareto frontier navigator (140) to select the best plan from a set of various auto-planned solutions. An interactive graphical user interface (400) is provided to the planner to navigate among convex combinations of auto-planned solutions. This proposed Pareto plan navigation can be considered as a further optional refinement process, which can be applied to find the best plan in those cases where auto-generated solutions are not fully satisfying the planner's requirements. The navigation tool (400) moves locally through a set of auto-generated plans and can potentially simplify the planner's decision making process and reduce the whole planning time on complex clinical cases from several hours to minutes.
摘要:
To perform appropriate survival selectin when generating an image processing program by using genetic programming. A processing unit (1b) selects an image processing program (21) from among a plurality of image processing programs (21, 22, 23, and so on) each generated by combining a plurality of partial programs; generates an image processing program (21a) by changing a part of the partial programs included in the image processing program (21); performs image processing on an input image (11), using the image processing program (21a); determines whether to pass the image processing program (21a) to the next generation, based on a comparison between one or more intermediate output images (31 and 32) that are output halfway through the image processing and a first target image (12); and replaces one of the image processing programs (21, 22, 23, and so on) with the image processing program (21a) when the image processing program (21a) is determined to be passed to the next generation.