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    METHOD AND SYSTEM FOR MICROBIOME ANALYSIS
    22.
    发明公开
    METHOD AND SYSTEM FOR MICROBIOME ANALYSIS 审中-公开
    方法和系统MIKROBIOMANALYSE

    公开(公告)号：EP3097211A2

    公开(公告)日：2016-11-30

    申请号：EP15740133.2

    申请日：2015-01-09

    申请人： Ubiome Inc.

    发明人： APTE, Zachary ,  RICHMAN, Jessica

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/689 ,  C12Q1/6869 ,  C12Q1/6888 ,  G06F19/22

    摘要： A method and system for analyzing a microbiome of an individual, comprising: providing a sampling kit to the individual at a location remote from the sample processing network, the sampling kit including a sample container having a lysing component and a sample preservation component and configured to receive a sample from a collection site of the individual; receiving the sample container with the sample from the collection site of the individual; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; identifying a set of microorganisms represented in the microorganism portion based upon performance of a mapping operation on portions of the microbiome sequence dataset; generating an analysis based upon a set of features related to the microorganism portion; and transmitting information derived from the analysis to the individual.

    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS
    29.
    发明公开
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS 审中-公开
    用于微生物学诊断和治疗的方法和系统

    公开(公告)号：EP3209803A1

    公开(公告)日：2017-08-30

    申请号：EP15852829.9

    申请日：2015-10-21

    申请人： Ubiome, Inc.

    发明人： APTE, Zachary ,  RICHMAN, Jessica ,  BEHBAHANI, Siavosh, Rezvan ,  ALMONACID, Daniel

    IPC分类号： C12Q1/68

    CPC分类号： G06F19/3418 ,  C12Q1/68 ,  C12Q1/6883 ,  C12Q1/689 ,  C12Q2600/118 ,  G06F19/00 ,  G06F19/10 ,  G06F19/12 ,  G06F19/28 ,  G06F19/30 ,  G16H20/10 ,  G16H50/20 ,  Y02A90/26

    摘要： A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    摘要翻译： 用于诊断和治疗受试者的免疫微生物功能障碍的方法，所述方法包括：从受试者群体接收一组生物样本; 为所述受试者群体生成微生物组成数据集和微生物组功能多样性数据集中的至少一个; 基于从微生物组合物数据集和微生物组功能多样性数据集中的至少一个提取的特征产生免疫微生物功能障碍的表征，其中所述表征诊断为克罗恩病，炎性肠病（IBD），肠易激综合征 综合征（IBS），溃疡性结肠炎和乳糜泻; 基于所述表征，产生配置成纠正所述免疫微生物功能障碍的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。