利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

28 条记录 (耗时 0.029 秒)

    HIGH FREQUENCY VIBRATION SPINDLE SYSTEM WITH NONCONTACT POWER TRANSMISSION AND METHOD FOR MANUFACTURING A RESTRAINING PART USED THEREIN
    21.
    发明公开
    HIGH FREQUENCY VIBRATION SPINDLE SYSTEM WITH NONCONTACT POWER TRANSMISSION AND METHOD FOR MANUFACTURING A RESTRAINING PART USED THEREIN 审中-公开

    公开(公告)号：EP3616830A1

    公开(公告)日：2020-03-04

    申请号：EP19191725.1

    申请日：2019-08-14

    申请人： National Chung-Hsing University

    发明人： CHEN, Jenq-Shyong ,  KO, Chuan-Wu ,  WANG, Hao-Tang

    IPC分类号： B23P25/00 ,  B24B1/04 ,  B23B29/12

    摘要： A high frequency vibration spindle system (100, 200) with non-contact power transmission and a method for manufacturing a restraining part (50, 240) used therein are disclosed. The high frequency vibration spindle system (100, 200) comprises: a spindle (10, 210); a toolholder (20, 220); an electric power transmission device (40, 230) including a first induction module (60, 250) and a second induction module (70, 260), wherein the second induction module (70, 260) is disposed at the spindle (10, 210) or the toolholder (20, 220), and the second induction module (70, 260) is adapted to receive an electric power from the first induction module (60, 250) in a non-contact electromagnetic induction manner; a transducer (30) adapted to be controlled to vibrate the tool (22) and being disposed at the toolholder (20, 220) and electrically connected with the second induction module (70, 260) to receive the electric power; and a restraining part (50, 240) located between the first induction module (60, 250) and the second induction module (70, 260). By the design of the restraining part (50, 240), the structural strength and stability of the second induction module (70, 260) can be improved, and the maximum rotational speed of the high frequency vibration spindle system (100, 200) can be increased.

    USE OF BUTENYLPHTHALIDE, USAGE METHOD THEREOF AND METHOD FOR PREPARING SAME INTO PHARMACEUTICAL COMPOSITION
    23.
    发明公开
    USE OF BUTENYLPHTHALIDE, USAGE METHOD THEREOF AND METHOD FOR PREPARING SAME INTO PHARMACEUTICAL COMPOSITION 审中-公开
    BUTENYLPHTHALID的使用，其使用方法和方法其制备的药物组合物

    公开(公告)号：EP3175851A1

    公开(公告)日：2017-06-07

    申请号：EP14898918.9

    申请日：2014-07-28

    申请人： National Chung Hsing University

    发明人： SU, Hong-Lin ,  CHANG, Chia-Yu ,  HWANG, Shiaw-Min ,  LU, Huai-En ,  HARN, Horng-Jyh ,  LIN, Shinn-Zong ,  LAI, Ping-Shan

    IPC分类号： A61K31/365 ,  A61P17/14 ,  A61P25/28

    CPC分类号： A61K31/365 ,  A61K8/4973 ,  A61K9/0014 ,  A61K36/23 ,  A61K36/28 ,  A61K2800/74 ,  A61Q7/00

    摘要： The present invention discloses use of butylidenephthalide (Bdph), a method of using the same, and a method for preparing a pharmaceutical composition containing the same. Because Bdph has the capability of promoting the hair growth and reducing the β-amyloid protein (Aβ) level in nerve cells, the efficacy of improving the health and appearance of a subject can be achieved by administrating an effective amount of Bdph to the subject. Specifically, the Bdph has the efficacy of preventing or treating neurodegenerative diseases such as Alzheimer's disease caused by excessive build up of Aβ in the cells, and as an active ingredient in a topical composition, the Bdph is effective in promoting the hair growth at the site where the Bdph is administered. Furthermore, the method for preparing a pharmaceutical composition containing Bdph comprises preparing the pharmaceutical composition through an organic synthesis reaction, wherein the Bdph is coated with a polymeric material such as F127 by covalent bonding of the polymeric material with the Bdph, thereby achieving the effect of reducing the cytotoxicity of the pharmaceutical composition for an organism.

    摘要翻译： 本发明自由圆盘使用丁烯酜的（BDPh），使用相同的方法，和制备含该化合物的药物组合物的方法。 因为BDPh具有促销廷的能力的所述毛发的生长和减少神经细胞的²淀粉样蛋白（安培）的水平，提高受治疗者的健康和外观的功效可以通过有效量BDPh的施用给受试者来实现。 具体而言，BDPh具有预防或治疗神经变性疾病的功效：如阿尔茨海默氏病通过在细胞A²的过度积聚引起的，如在局部用组合物的活性成分，所述BDPh是有效的促销婷头发的生长在现场 其中BDPh施用。 进一步，用于制备含有BDPh包括通过有机合成反应来制备所述药物组合物的药物组合物，worin的BDPh的方法被涂覆有聚合物材料：如通过与BDPh聚合物材料的共价键合，从而实现的效果F127 减少所述药物组合物的细胞毒性在生物体。

    PHOTOSENSITIZER PARTICLES FOR MEDICAL IMAGING AND/OR PHOTODYNAMIC THERAPY
    25.
    发明公开
    PHOTOSENSITIZER PARTICLES FOR MEDICAL IMAGING AND/OR PHOTODYNAMIC THERAPY 有权
    FOTOSENBILISATORTEILCHENFÜRDIE MEDISINISCHE BILDGEBUNG UND / ODER FOTODYNAMISCHE THERAPIE

    公开(公告)号：EP2996677A1

    公开(公告)日：2016-03-23

    申请号：EP14801516.7

    申请日：2014-05-16

    申请人： DCB-USA LLC ,  National Chung-Hsing University

    发明人： LAI, Ping-Shan ,  HSU, Chia-Yen

    IPC分类号： A61K9/14 ,  A61K47/30 ,  A61K49/12

    摘要： Disclosed herein are photosensitizer particle contrast agents suitable for medical imaging and/or photodynamic therapy. The photosensitizer particle contrast agent has a shell and a core encased by the shell. The shell consists essentially of multiple photosensitizer conjugates. Each photosensitizer conjugate consists of a photosensitizer and at least one biodegradable polymer covalently bound to the photosensitizer. According to certain examples, the core has an echogenic contrast-enhancing material loaded therein. In alternative examples, the photosensitizer of at least one of the multiple photosensitizer conjugates has a magnetic contrast-enhancing agent, e.g., a paramagnetic ion, chelated thereto. Also disclosed herein are methods for medical imaging which use imaging compositions containing the photosensitizer particle contrast agents taught in the present disclosure.

    摘要翻译： 本文公开了适用于医学成像和/或光动力疗法的光敏剂颗粒造影剂。 光敏剂颗粒造影剂具有由壳包裹的壳和芯。 壳基本上由多个光敏剂缀合物组成。 每个光敏剂共轭物由光敏剂和共价结合到光敏剂上的至少一种可生物降解的聚合物组成。 根据某些实例，芯具有装载在其中的回声对比增强材料。 在替代实例中，多个光敏剂共轭物中的至少一个的光敏剂具有与其螯合的磁性对比度增强剂，例如顺磁性离子。 本文还公开了使用含有本发明中教导的光敏剂颗粒造影剂的成像组合物的医学成像方法。