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公开(公告)号：EP2593463B1
公开(公告)日：2020-05-06
申请号：EP11807418.6
申请日：2011-07-12
发明人： SELBO, Jon , TENG, Jing , KABIR, Mohammed, A. , GOLDEN, Pam
IPC分类号： A61K9/14 , A61K9/16 , A61K9/48 , A61K9/10 , A61K31/437 , C07D498/22
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公开(公告)号：EP3140313B1
公开(公告)日：2020-02-26
申请号：EP15789810.7
申请日：2015-05-04
发明人： GOLDEN, Pam , FODOR, Anthony , BORTEY, Enoch , FORBES, William
IPC分类号： C12Q1/6883
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公开(公告)号：EP3140313A4
公开(公告)日：2017-12-27
申请号：EP15789810
申请日：2015-05-04
发明人： GOLDEN PAM , FODOR ANTHONY , BORTEY ENOCH , FORBES WILLIAM
CPC分类号： A61K31/437 , C07G11/00 , C12Q1/04 , C12Q1/68 , C12Q1/6809 , C12Q1/6883 , C12Q1/689 , C12Q2600/158 , G01N2800/065 , G01N2800/52 , C12Q2535/122 , C12Q2537/165
摘要： The instant application provides methods of diagnosing and treating a subject having IBS. In certain embodiments, the methods also include diagnosing subjects who will respond to IBS treatment with rifaximin.
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公开(公告)号：EP3140313A1
公开(公告)日：2017-03-15
申请号：EP15789810.7
申请日：2015-05-04
发明人： GOLDEN, Pam , FODOR, Anthony , BORTEY, Enoch , FORBES, William
IPC分类号： C07G11/00
摘要： The instant application provides methods of diagnosing and treating a subject having IBS. In certain embodiments, the methods also include diagnosing subjects who will respond to IBS treatment with rifaximin.
摘要翻译： 该即时应用提供诊断和治疗具有IBS的受试者的方法。 在某些实施方案中，所述方法还包括诊断将用利福昔明治疗IBS治疗的受试者。
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25.发明公开
公开(公告)号：EP2894982A4
公开(公告)日：2016-06-22
申请号：EP13836419
申请日：2013-09-13
发明人： NEFF GUY
CPC分类号： A61K31/437
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26.发明公开
公开(公告)号：EP2895169A1
公开(公告)日：2015-07-22
申请号：EP13837021.8
申请日：2013-09-12
发明人： PIMENTEL, Mark , CHANG, Christopher
IPC分类号： A61K31/495
CPC分类号： A61K31/437 , A61K45/06 , A61K2300/00
摘要： Methods of administering a composition comprising rifaximin to a subject in need thereof are provided, wherein the methods do not increase development of rifampicin resistance to a
Staphylococcus spp. Methods of reducing the development of rifampicin resistance to a
Staphylococcus spp. are also provided, comprising administering a composition comprising rifaximin to a subject in need thereof.-
27.发明公开METHODS OF ADMINISTERING RIFAXIMIN FOR WEIGHT LOSS AND TREATMENT OF OBESITY 审中-公开行政利福昔明的减肥和肥胖症的处理方法
公开(公告)号：EP2894983A1
公开(公告)日：2015-07-22
申请号：EP13836879.0
申请日：2013-09-13
发明人： RANDALL, Charles, W.
CPC分类号： A61K31/437
摘要： Methods of reducing weight in a subject are provided, wherein the methods comprise administering a composition comprising an effective amount of rifaximin to a subject in need of treatment for weight loss. In some embodiments, the subject is considered obese (BMI > 30).
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公开(公告)号：EP2782581A4
公开(公告)日：2015-05-20
申请号：EP12844538
申请日：2012-10-27
CPC分类号： A61K31/538 , A23L33/10 , A23L33/16 , A61K9/48 , A61K31/70 , A61K31/7004 , A61K33/00 , A61K33/06 , A61K33/14 , A61K47/02 , A61K47/10 , A61K2300/00
摘要： The invention provides compositions for use in purgatives, for use as purgatives, and to methods for inducing purgation of the colon. In alternative embodiments, the invention provides compositions, e.g., a purgative, comprising: a water-soluble sodium salt (especially sodium sulphate), a water-soluble potassium salt (especially potassium sulphate), and a water-soluble magnesium salt (especially magnesium sulphate); and, compositions further comprising: a bisoxatin, or a detergent stool softening agent (such as sodium picosulphate) and/or a water-soluble sugar (such as xylose or equivalent); or, compositions having these ingredients at different amounts, but at equivalent proportions. In alternative embodiments, the invention provides purgative compositions comprising electrolytes, salts, sugars, bisoxatin, dyes and biofilm disruptors.
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公开(公告)号：EP1931354A2
公开(公告)日：2008-06-18
申请号：EP06802343.1
申请日：2006-08-24
发明人： LOCKHART, Joseph , SWANSON, Brock , JOHNSON, Lorin
IPC分类号： A61K31/655
CPC分类号： A61K31/655 , A61K9/20 , A61K9/4858 , A61K31/609 , A61K47/12 , A61K47/38
摘要： The invention relates to formulations and dosage schedules of balsalazide. The invention further relates to methods of producing pharmaceutical formulations of balsalazide.
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30.发明公开USE OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES AS COLON CANCER CHEMOPREVENTATIVE AND CHEMOTHERAPEUTIC AGENTS 失效用2-羟基-5- phenylazobenzoic衍生物用于预防CHEMO作为活性成分和结肠癌的化疗
公开(公告)号：EP0738152A4
公开(公告)日：2000-12-13
申请号：EP95907293
申请日：1995-01-06
IPC分类号： A61K31/60 , A61K31/606 , A61K31/655 , A61P35/00 , A61P43/00 , A61K31/615
CPC分类号： A61K31/655
摘要： The present invention provides a method of colon cancer chemoprevention or chemotherapy comprising administering to an individual suffering from colon cancer or at risk to develop colon cancer a pharmaceutical composition comprising an effective amount of a 2-hydroxy-5-phenylazobenzoic acid derivative or an ester of an active metabolite or an oxidation product of an active metabolite thereof, or a pharmacologically acceptable salt of the 2-hydroxy-5-phenylazobenzoic acid derivative or an ester or an active metabolite or an oxidation product of an active matabolite thereof.
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