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    ANALYSIS METHOD USING REPORTER (LABEL) INTERMOLECULAR INTERACTION
    32.
    发明公开
    ANALYSIS METHOD USING REPORTER (LABEL) INTERMOLECULAR INTERACTION 有权
    利用记号（标记）分子间相互作用的分析方法

    公开(公告)号：EP1382965A1

    公开(公告)日：2004-01-21

    申请号：EP02720570.7

    申请日：2002-04-23

    申请人： Eiken Kagaku Kabushiki Kaisha ,  Nagamune, Teruyuki

    发明人： NAGAMUNE, Teruyuki ,  UEDA, Hiroshi ,  OHIRO, Yoshiyuki, c/o Eiken Kagaku Kabushiki K. ,  SHIBATA, Norio, c/o Eiken Kagaku Kabushiki Kaisha

    IPC分类号： G01N33/542

    CPC分类号： G01N33/54306 ,  G01N33/533 ,  G01N33/542 ,  G01N33/582

    摘要： The present invention provides, in the use of the energy transfer phenomenon in a detection system for the measurement of the concentration of a material, a method for controlling the spatial arrangement of an energy donor and an energy acceptor in a reaction complex in order to carry out the measurement with good precision and high sensitivity, and a measurement system using the method.
    Two types of material having affinity for the subject material to be measured are respectively labeled with a combination of reporters that give rise to energy transfer; those that have been thus obtained by labeling these materials are each further labeled with materials that have weak affinity for each other to give reagents, which are then mixed with a sample to give the reaction complex. Each of the materials is brought into spatial proximity by binding based on the affinity among the materials having weak affinity for each other in the reaction complex, and since that condition is stably maintained, a more efficient energy transfer occurs.

    摘要翻译： 本发明提供了在用于测量材料浓度的检测系统中使用能量转移现象的方法，用于控制反应复合物中能量供体和能量受体的空间排列以便携带 高精度，高灵敏度的测量，以及使用该方法的测量系统。 对待测物体具有亲和性的两种材料分别用导致能量转移的报道分子的组合进行标记; 通过对这些材料进行标记而获得的那些每个都进一步用对彼此具有弱亲和力的材料进行标记以提供试剂，然后将这些试剂与样品混合以提供反应复合物。 基于在反应复合物中彼此具有弱亲和性的材料之间的亲和力，通过结合将每种材料置于空间上接近，并且由于稳定地保持该条件，发生更有效的能量转移。

    FECES PICK-UP CONTAINER FOR TRANSPORTATION
    34.
    发明公开
    FECES PICK-UP CONTAINER FOR TRANSPORTATION 失效
    AUFNAME-UNDTRANSPORTBEHÄLTERFÜRFÄZES。

    公开(公告)号：EP0638803A1

    公开(公告)日：1995-02-15

    申请号：EP94903018.3

    申请日：1993-12-17

    申请人： EIKEN KAGAKU KABUSHIKI KAISHA

    发明人： URATA, Takeyoshi ,  URANO, Hiromi ,  ASANO, Shinichiro ,  KIKUCHI, Tatsunori ,  AOTA, Shigeru ,  HAYASHI, Hiroaki ,  ICHIKAWA, Yoshiharu

    IPC分类号： G01N33/48 ,  A61B10/00 ,  B01L3/00 ,  G01N33/52

    CPC分类号： B01L3/502 ,  A61B10/0038 ,  G01N33/528 ,  G01N2001/005 ,  G01N2001/4088

    摘要： A transportable feces pick-up container comprising: a tubular container body (23) capable of containing therein a solution; a lid member (25) including a feces pick-up bar (24); a partition wall (26) in the container body; a filter (27-29); and a filtered solution dropping portion (30); wherein the outer peripheral portion of the filter is clamped and fixed between a stepped portion in the container body and an end face of the dropping portion (30). This container is high in an effective filtering area rate. Furthermore, this container is easy to transport and can be delivered and/or returned, for example, in a mailing means such as a mail envelope, so that it is very valuable to use.

    摘要翻译： 一种可移动的粪便拾取容器，包括：能够在其中容纳溶液的管状容器主体（23）; 包括粪便拾取杆（24）的盖构件（25）; 容器主体中的分隔壁（26）; 过滤器（27-29）; 和过滤溶液滴下部分（30）; 其特征在于，所述过滤器的外周部被夹持固定在所述容器本体的台阶部与所述下落部（30）的端面之间。 该容器的有效过滤面积率高。 此外，该容器易于运输，并且可以例如在诸如邮件信封的邮寄手段中被传送和/或返回，使得使用非常有价值。

    METHOD FOR DETECTING TARGET BASE SEQUENCE, METHOD FOR DESIGNING AND PRODUCING PROBE, AND KIT
    39.
    发明公开
    METHOD FOR DETECTING TARGET BASE SEQUENCE, METHOD FOR DESIGNING AND PRODUCING PROBE, AND KIT 审中-公开

    公开(公告)号：EP3533880A1

    公开(公告)日：2019-09-04

    申请号：EP17865651.8

    申请日：2017-10-25

    申请人： Eiken Kagaku Kabushiki Kaisha

    发明人： MICHIYUKI, Satoru ,  KANDA, Hidetoshi

    IPC分类号： C12Q1/68 ,  G01N21/78 ,  C12N15/09

    摘要： The present invention addresses the issue of providing a target base sequence detection method, etc., whereby a determination can be readily made regarding whether or not a target base sequence is present in a nucleic acid sample. A fluorescent-labeled detection probe and a competitive probe are added to a nucleic acid sample and caused to hybridize with the nucleic acid in the sample, the fluorescence intensity is measured while changing the temperature of the reaction sample, and first order differentiation is performed on a temperature- fluorescence intensity curve. The fluorescent-labeled detection probe and competitive probe base length, base sequence, and amount to be added to nucleic acid samples are determined such that the first order derivative curve for a control target reaction sample including a target base sequence has a peak but the first order derivative curve for a control non-target reaction sample including a non-target base sequence does not substantially have a peak, when: the fluorescent-labeled detection probe and the competitive probe are added to both the control target nucleic acid sample and the control non-target nucleic acid sample; the fluorescence intensity is measured while the temperature of both the obtained control target reaction sample and the control non-target reaction sample are changed; and first order differentiation is performed on a temperature- fluorescence intensity curve.

    PRESERVATIVE SOLUTION FOR HEME PROTEIN, AND METHOD FOR STABILIZING HEME PROTEIN
    40.
    发明公开
    PRESERVATIVE SOLUTION FOR HEME PROTEIN, AND METHOD FOR STABILIZING HEME PROTEIN 审中-公开
    HEME蛋白的保存液和稳定HEME蛋白的方法

    公开(公告)号：EP3279660A1

    公开(公告)日：2018-02-07

    申请号：EP16773083.7

    申请日：2016-03-31

    申请人： Eiken Kagaku Kabushiki Kaisha

    发明人： SAKATA Kozue ,  SUGO Shin ,  YASUI Ryota

    IPC分类号： G01N33/531 ,  C07K14/805 ,  G01N1/28

    CPC分类号： G01N1/28 ,  C07K14/805 ,  G01N33/531

    摘要： An object of the present invention is to provide a novel preservative solution for a heme protein and a method for stabilizing a heme protein, which are effective against denaturation or degradation of a heme protein, and the present invention specifically relates to a preservative solution for a heme protein comprising a disulfonic acid or a salt thereof, and a method for stabilizing a heme protein, which involves bringing a disulfonic acid or a salt thereof into coexistence in a sample comprising a heme protein.

    摘要翻译： 本发明的一个目的是提供一种新的血红素蛋白质保存液和稳定血红素蛋白质的方法，它们能有效地抵抗血红素蛋白质的变性或降解，本发明特别涉及一种用于 包含二磺酸或其盐的血红素蛋白质以及稳定血红素蛋白质的方法，其包括使二磺酸或其盐共存于包含血红素蛋白质的样品中。