公开(公告)号：EP2536879B1

公开(公告)日：2015-09-16

申请号：EP11745221.9

申请日：2011-02-17

申请人： Rutgers, The State University of New Jersey

发明人： NOSKER, Thomas ,  LYNCH, Jennifer

IPC分类号： E01B3/36 ,  E01B3/44

CPC分类号： E01B3/44 ,  E01B3/00

公开(公告)号：EP2909028A1

公开(公告)日：2015-08-26

申请号：EP13846759.2

申请日：2013-03-14

申请人： Rutgers, The State University of New Jersey

发明人： NOSKER, Thomas ,  LYNCH, Jennifer ,  HENDRIX, Justin ,  KEAR, Bernard ,  CHIU, Gordon ,  TSE, Stephen

IPC分类号： B32B9/00 ,  C08L63/00

CPC分类号： C08K3/04 ,  B29C47/6043 ,  B29C47/64 ,  B29K2105/162 ,  C08J3/201 ,  C08J5/005 ,  C08J2300/22 ,  C08J2381/06 ,  C08K2201/011

摘要： A method for forming a graphene-reinforced polymer matrix composite is disclosed. The method includes distributing graphite microparticles into a molten thermoplastic polymer phase; and applying a succession of shear strain events to the molten polymer phase so that the molten polymer phase exfoliates the graphite successively with each event until at least 50% of the graphite is exfoliated to form a distribution in the molten polymer phase of single- and multi-layer graphene nanoparticles less than 50 nanometers thick along the c-axis direction.

公开(公告)号：EP1945755B1

公开(公告)日：2015-01-14

申请号：EP06788711.7

申请日：2006-07-26

申请人： Rutgers, the State University of New Jersey

发明人： GENNARO, Maria Laura

IPC分类号： C12N15/09 ,  G01N33/53

CPC分类号： A61K39/04 ,  G01N33/53 ,  G01N33/5695

公开(公告)号：EP2718241A1

公开(公告)日：2014-04-16

申请号：EP12796640.6

申请日：2012-06-07

申请人： Rutgers, the State University of New Jersey

发明人： RIMAN, Richard, E. ,  NYE, Thomas, E. ,  ATAKAN, Vahit ,  VAKIFAHMETOGLU, Cekdar ,  LI, Qinghua ,  LING, Tang

IPC分类号： C04B18/06 ,  C04B7/02

CPC分类号： C04B28/10 ,  C04B28/182 ,  C04B28/184 ,  Y02W30/91 ,  Y02W30/92 ,  Y02W30/93 ,  Y02W30/94 ,  Y02W30/95 ,  Y02W30/97 ,  C04B18/08 ,  C04B18/162 ,  C04B14/28 ,  C04B18/106 ,  C04B18/241 ,  C04B18/0409 ,  C04B18/12 ,  C04B14/22 ,  C04B18/101 ,  C04B7/345 ,  C04B38/00 ,  C04B40/0231 ,  C04B18/146

摘要： A method for producing a reaction product including at least one synthetic formulation that carbonates sufficiently, said method comprising: providing a first raw material, having a first concentration of M; providing a second raw material, having a second concentration of Me; and mixing the first raw material and the second raw material to produce a reaction product that includes at least one synthetic formulation having the general formula M
a Me
b O
c , MaMeb(OH)
d , M
a Me
b O
c (OH)
d or M
a Me
b O
c (OH)
d (H20)
e , wherein M comprises at least one metal that can react to form a carbonate and Me is at least one element that can form an oxide during the carbonation reaction, wherein the at least one synthetic formulation is capable of undergoing a carbonation reaction, and wherein the at least one synthetic formulation is capable of undergoing volume change during the carbonation reaction.

公开(公告)号：EP2566326A1

公开(公告)日：2013-03-13

申请号：EP11778157.5

申请日：2011-05-03

申请人： Rutgers, The State University of New Jersey

发明人： SIMON, James, E. ,  WU, Qingli ,  WELCH, Cara

IPC分类号： A01N43/16 ,  A61K31/35

CPC分类号： C07D405/10 ,  A61K36/185 ,  C07D405/04

摘要： This invention provides the methods of separation and identification of a novel type of piperidine flavan alkaloids from an African herbal tea, the leaves of
Combretum micranthum commonly known as kinkeliba, and the procedures for preparing the total piperidine flavan alkaloids (TPFA). In particular, this invention relates to the use of the plant extract that may contain TPFA as anti-diabetic agents in treatment of metabolic disorders and other applications related to this new chemical structure and derivatives thereof.

公开(公告)号：EP2403856B1

公开(公告)日：2012-12-19

申请号：EP10708472.5

申请日：2010-03-05

申请人： Rutgers, The State University of New Jersey ,  University Of Medicine And Dentistry Of New Jersey

发明人： LAVOIE, Edmond, J. ,  FENG, Wei ,  LIU, Leroy, F.

IPC分类号： C07D491/04 ,  A61K31/4355 ,  A61P35/00 ,  A61P35/02

CPC分类号： C07D491/04 ,  A61K31/4355

摘要： The invention provides compounds of formula I: wherein A, B, X, and Y have any of the values defined in the specification, as well as pharmaceutical compositions comprising such compounds, processes for preparing such compounds, and therapeutic methods for treating cancer and other topoisomerase mediated conditions.

公开(公告)号：EP2459638A1

公开(公告)日：2012-06-06

申请号：EP10805160.8

申请日：2010-07-31

申请人： Rutgers, The State University of New Jersey

发明人： KOHN, Joachim, B. ,  BOLIKAL, Durgadas ,  ROJAS, Ramiro

IPC分类号： C08K5/00

CPC分类号： C08G79/02 ,  A61K47/59 ,  A61K47/60 ,  C08G79/025

摘要： The invention relates to novel monomers of Formula (I) useful for preparation of phase-separated biocompatible polymers or polymer compositions. These polymers or polymer compositions may be bioresorbable and/or biodegradable and have desirable mechanical properties, such as fracture and/or fatigue toughness, which have not been a primary design criteria for such polymers previously. The polymers or polymer compositions are useful in a variety of medical applications, such as in the fabrication of medical devices. Therefore, methods for preparing these polymers or polymer compositions and medical devices are also encompassed by this disclosure.

公开(公告)号：EP2459637A1

公开(公告)日：2012-06-06

申请号：EP10805159.0

申请日：2010-07-31

申请人： Rutgers, The State University of New Jersey

发明人： BOLIKAL, Durgadas ,  KOHN, Joachim, B. ,  ROJAS, Ramiro

IPC分类号： C08K5/00

CPC分类号： C08G79/02 ,  A61K47/59 ,  A61K47/60 ,  C08G79/025

摘要： The present invention relates to new classes of biocompatible polymers comprising at least one repeating unit derived from a compound of Formula (I) as defined in the claims and specification. These polymers may be biodegradable and bioresorble, and, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations. Therefore, methods for preparing these polymers and medical devices prepared therefrom are also encompassed by this disclosure.

公开(公告)号：EP2448954A1

公开(公告)日：2012-05-09

申请号：EP10733077.1

申请日：2010-07-01

申请人： Rutgers, The State University of New Jersey

发明人： JONES, Roger A. ,  GAFFNEY, Barbara L.

IPC分类号： C07H21/02 ,  C07H19/20 ,  A61K31/7084

CPC分类号： C07H19/213 ,  C07H23/00

摘要： The invention provides methods for the synthesis of cyclic dinucleotides and thiophosphate analogs thereof as well as a new family of analogs of cyclic diguanosine monophosphate that includes a series of seven phosphorothioate derivatives that includes diastereomers of mono-, di-, and trithiophosphates.

公开(公告)号：EP2406717A1

公开(公告)日：2012-01-18

申请号：EP10751531.4

申请日：2010-03-13

申请人： Rutgers, The State University of New Jersey

发明人： YAO, Danfeng ,  WU, Chehai ,  STEFAN, Deian

IPC分类号： G06F11/30

CPC分类号： H04L63/145 ,  G06F21/316 ,  G06F21/32 ,  G06F21/566 ,  G06F2221/2133

摘要： A system and method for distinguishing human input events from malware- generated events includes one or more central processing units (CPUs), one or more input devices and memory. The memory includes program code that when executed by the CPU causes the CPU to obtain a first set of input events from a user utilizing the input device. The first input events are used to obtain or derive a feature indicative of the user, such as a multi-dimensional feature vector as provided by a support vector machine. Second input events are then obtained, and the second input events are classified against the feature to determine if either the user or malware initiated the second input events.