公开(公告)号：EP1718953A4

公开(公告)日：2008-02-20

申请号：EP05711948

申请日：2005-01-20

Applicant: NALCO CO

Inventor： BANKS RODNEY H

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01N33/18 ,  G01N2021/157 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/064

Abstract: Described and claimed is an interchangeable tip-open cell fluorometer comprising a housing and a fluorometric probe tip interchangeably connected to the housing, the probe tip including a probe tip housing defining an open cell and enclosing a probe optical arrangement, the probe optical arrangement including an excitation source and a fluorescence detector wherein the excitation source is aimed directly into the fluorescence detector such that a sample can be fluorometrically detected. Also claimed is a method of using this interchangeable tip-open cell fluorometer for detecting fluorescent signals emitted by one or more fluorophores from samples from a natural or industrial water system. The fluorometer, when coupled with a controller, is capable of monitoring and optionally controlling an industrial process or system.

公开(公告)号：EP1856509A1

公开(公告)日：2007-11-21

申请号：EP06723196.9

申请日：2006-03-03

Applicant: ESE Embedded System Engineering GmbH

Inventor： GRULER, Roman

IPC: G01N21/64 ,  A61B3/10

CPC classification number: G01N21/6486 ,  B33Y80/00 ,  G01N21/645 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2201/024

Abstract: Disclosed is a fluorescence meter for analyzing a sample (3), comprising a main beam path (5) and at least one optical module. The inventive fluorescence meter is embodied so as to provide at least one electromagnetic beam (27) for exciting the sample and receive at least one electromagnetic beam (29, 31) emitted by the sample, at least some sections of at least two of said electromagnetic beams being located on one plane while extending along the main beam path.

公开(公告)号：EP1718953A2

公开(公告)日：2006-11-08

申请号：EP05711948.9

申请日：2005-01-20

Applicant: Nalco Company

Inventor： BANKS, Rodney, H.

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01N33/18 ,  G01N2021/157 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/064

Abstract: Described and claimed is an interchangeable tip-open cell fluorometer comprising a housing and a fluorometric probe tip interchangeably connected to the housing, the probe tip including a probe tip housing defining an open cell and enclosing a probe optical arrangement, the probe optical arrangement including an excitation source and a fluorescence detector wherein the excitation source is aimed directly into the fluorescence detector such that a sample can be fluorometrically detected. Also claimed is a method of using this interchangeable tip-open cell fluorometer for detecting fluorescent signals emitted by one or more fluorophores from samples from a natural or industrial water system. The fluorometer, when coupled with a controller, is capable of monitoring and optionally controlling an industrial process or system.

公开(公告)号：EP1121581B8

公开(公告)日：2006-06-21

申请号：EP99947384.6

申请日：1999-09-18

Applicant: Carl Zeiss AG

Inventor： VÖLCKER, Martin ,  FATTINGER, Christof

IPC: G01N21/25 ,  G02B3/00 ,  G02B5/04

CPC classification number: G01N21/6452 ,  G01N21/253 ,  G01N2201/024 ,  G02B3/005 ,  G02B3/0068 ,  G02B5/045

Abstract: The invention relates to an imaging system for optical automatic analysers, especially fluorescence readers. On the sample side, the imaging system contains a cylindrical lens array (6) and a prism array (7), which is arranged upstream of the cylindrical lens array. The prismatic effect of the prisms (7a-7c) of the prism array (7) lies in the direction of the cylinder axes of the cylindrical lenses (6a-6c). Together with a telescopic imaging system (8, 11), the inventive imaging system creates a number of parallel cylindrical focussing volumes between the cylindrical lens array (6) and a detector array (10), these focussing volumes being slanted towards the optical axis of the telescopic system in relation to the vertical. The arrangement enables the detection of fluorescence with a large aperture in one direction, and at the same time enables depth selective analysis of the fluorescence signal, especially the discrimination of the fluorescent radiation originating from the areas around the bases of the sample containers from the fluorescent radiation originating from the solution above. With the focussing volumes that are slanted towards the bases of the sample containers, the imaging system ensures that the fluorescence from the areas around the bases of the sample containers (5a-5c) is detected with the same sensitivity even when the heights of the bases vary in the individual sample containers.

公开(公告)号：EP1451573B1

公开(公告)日：2006-01-18

申请号：EP02796892.4

申请日：2002-12-03

Applicant: Adiv Association ,  Ofival - Office National Interprofessionnel des Viandes de l'Elevage et de l'Aviculture ,  Interbev - Association Nationale Interprofessionelle du Betail et des Viandes

Inventor： FRENCIA, Jean-Pierre ,  DUFOUR, Eric

IPC: G01N33/02 ,  G01N21/64

CPC classification number: G01N21/6486 ,  G01N33/02 ,  G01N33/12 ,  G01N2021/6484 ,  G01N2201/0221 ,  G01N2201/024

Abstract: The invention concerns a method characterized in that it consists in front fluorescence spectroscopy measurement, said measurement being non-invasive and based on a light source projected on a specific meat zone, measuring the fluorescence spectrum emitted by the fluorophores of said examined zone, said spectrum being addressed in a spectrometer (5) connected to a computer (6) including a system for acquiring and mathematical processing of data, capable of processing said spectrum to deduce therefrom parameters representing the tenderness of the meat or the freshness of the fish, and the light energy exciting the fluorophores is established on a wavelength of 250 to 290 nm corresponding to the fluorophore exciting wavelength and in particular protein tryptophans, aromatic amino acids and nucleic acids.

公开(公告)号：EP1517135A1

公开(公告)日：2005-03-23

申请号：EP04396056.6

申请日：2004-08-31

Applicant: WALLAC OY

Inventor： Harju, Raimo ,  Salonen, Janne ,  Turunen, Hannu

IPC: G01N21/64 ,  G01N21/76 ,  G02B6/26 ,  G01N21/25

CPC classification number: G01N21/763 ,  G01N21/6452 ,  G01N2201/024 ,  G02B6/0001

Abstract: The present invention relates generally to the field of biochemical laboratory instrumentation for different applications of measuring properties of samples on e.g. microtitration plates and corresponding sample supports. The object of the invention is achieved by providing an optical measurement instrument for photoluminescence, chemiluminescence and/or AplhaScreen measurements wherein different optical modules are used for alternative measurements. The excitation pulses for the alternative measurements are guided via two different routes to the optical module, said routes reaching the module in different angles. This way it is possible to use alternative radiation sources without optical switches and without changing the optical system. The object of the invention is further achieved by providing an additional lens in the optical module when a thermo plate is used. This way it is possible to achieve a correct optical focus in different measurement modes not depending on the use of the thermo plate.

Abstract translation: 本发明一般涉及用于不同应用样品的测量性质的生化实验室仪器领域。 微量滴定板和相应的样品支架。 本发明的目的是通过提供用于光致发光，化学发光和/或AplhaScreen测量的光学测量仪器来实现，其中不同的光学模块用于替代测量。 用于替代测量的激励脉冲通过两个不同的路由被引导到光学模块，所述路径以不同的角度到达模块。 这样就可以使用没有光开关的替代辐射源，而不改变光学系​​统。 当使用热板时，通过在光学模块中提供附加透镜来进一步实现本发明的目的。 这样可以在不同于热板的使用的情况下在不同的测量模式下实现正确的光学焦点。

公开(公告)号：EP1400801A1

公开(公告)日：2004-03-24

申请号：EP03396082.4

申请日：2003-09-09

Applicant: WALLAC OY

Inventor： Isaksson, Christer ,  Ojala, Markku ,  Salonen, Janne

IPC: G01N21/76 ,  G01N21/25 ,  G01N21/63

CPC classification number: G01N21/6452 ,  G01N21/253 ,  G01N21/76 ,  G01N2201/024

Abstract: The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more accurate instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invention is achieved by providing an optical measurement instrument for photoluminescence and chemiluminescence measurements wherein there is chemiluminescence detector (291) in such a proximity to the sample (282) that the emission radiation from the sample (282) may reach the detector (291) via a direct path. Attenuation caused by optical fibres and lenses can be totally avoided. This way it is possible to achieve an essentially improved accuracy of the chemiluminescence measurement as well as an improved overall efficiency of the optical measurements.

Abstract translation: 本发明一般涉及生化实验室领域。 更具体地，本发明涉及用于例如设备的改进和更准确的设备的功能。 荧光计，光度计和光度计。 本发明的目的是通过提供一种用于光致发光和化学发光测量的光学测量仪器实现，其中在样品（282）附近存在化学发光检测器（291），使得来自样品（282）的发射辐射可到达检测器 （291）通过直接路径。 可以完全避免光纤和镜头引起的衰减。 通过这种方式，可以实现化学发光测量的基本上提高的精度以及改进的光学测量的总体效率。

公开(公告)号：EP1291625A1

公开(公告)日：2003-03-12

申请号：EP02396135.2

申请日：2002-09-06

Applicant: WALLAC OY

Inventor： Aronkytö, Petri ,  Harju, Raimo ,  Myllynpää, Asko

IPC: G01J3/02 ,  G01N21/64

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0275 ,  G01N21/253 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/024

Abstract: The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more efficient instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invention is achieved by providing an optical measurement instrument where there is an interface (218, 223, 233a, 233b, 238) for a changeable optical module (240), the interface being adapted for at least one excitation beam and at least two emission beams. This allows performing various types of measurements by changing an optical module. The change of module and related parameters can be performed automatically controlled by software. It is also possible to easily upgrade the instrument for new types of measurements by just providing the instrument with a new optical module and the related software.

Abstract translation: 本发明一般涉及生化实验室领域。 更具体地，本发明涉及用于例如设备的改进和更有效的设备的功能。 荧光计，光度计和光度计。 本发明的目的通过提供一种光学测量仪器实现，其中存在用于可变光学模块（240）的界面（218,223,233a，233b，238），所述界面适用于至少一个激发光束 最少两个发射光束。 这允许通过改变光学模块执行各种类型的测量。 模块和相关参数的更改可以由软件自动控制。 只需向仪器提供新的光学模块和相关软件，也可轻松升级仪器进行新型测量。

公开(公告)号：EP0858592B1

公开(公告)日：2002-11-27

申请号：EP96931082.0

申请日：1996-09-20

Applicant: Thermo Labsystems Oy

Inventor： TUUNANEN, Jukka ,  PRIHA, Matti ,  TUPAKKA, Heikki ,  KÄRMENIEMI, Timo

IPC: G01N21/01 ,  G01N21/64

CPC classification number: G01N21/253 ,  G01N2201/024

Abstract: The invention relates to an optical analyser wherein measuring light is directed from a sample to the detector. The apparatus has an optics module (15) which has a detector and optical means for directing light emitted by the sample to the detector and which module can be positioned alternatively either so that light is directed to the detector from above the sample or so that light is directed to the detector from below the sample. The invention is usable in particular in fluorometers and in luminometers.

公开(公告)号：EP1004056A1

公开(公告)日：2000-05-31

申请号：EP98939349.1

申请日：1998-08-11

Applicant: Bio-Rad Laboratories

Inventor： HEFFELFINGER, David, M. ,  BATTERSON, Rebecca, Ann ,  SALGADO, Renato

IPC: G03B42/00

CPC classification number: G03B42/00 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6471 ,  G01N2021/6484 ,  G01N2201/024

Abstract: An apparatus capable of measuring quantities of biological or other types of samples that have been labeled using any of a variety of techniques including fluorescence, radioisotopes, enzyme activated light emitting chemicals and enzyme activated fluorescent materials is provided. The provided scanner includes a source module (113) that preferably contains an internal laser emitting two different wavelengths of approximately the same intensity. An optional external light source may be coupled to the source module, thus adding further flexibility through the addition of other wavelengths (e.g. UV, visible, mid-IR, and IR). The scanner also includes a detection module. Within the detection module (115) are two detectors, thus allowing the simultaneous detection of multiple wavelengths. A bifurcated optical cable (111) is used to transfer the excitation and/or readout light from the source module to the sample and subsequently transfer the emitted and/or scattered light from the sample to the detection module.