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公开(公告)号:EP3805213A3
公开(公告)日:2021-06-09
申请号:EP20210246.3
申请日:2016-06-17
发明人: AOYAMA, Hikaru , MATSUI, Maki , SAKANISHI, Keita , IWASA, Takao , KOBAYASHI, Tomomi , HIRATA, Koichi
IPC分类号: C07D401/14 , C07D401/04 , C07D403/04 , C07D231/12 , C07D231/14 , C07D231/16 , C07D231/38 , C07D231/40 , C07D249/06 , C07D513/04 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/90 , A01N47/18 , A01P7/02 , A01P7/04
摘要: The present invention provides a compound represented by formula (I), (in the formula, A 1 and A 2 each independently represents a carbon atom or a nitrogen atom; X 1 represents an unsubstituted or substituted C1-6 alkyl group or the like; n represents an integer of 0 to 4; R 1 represents an unsubstituted or substituted C1-6 alkylthio group or the like; B 1 and B 4 each independently represent a carbon atom, a nitrogen atom or the like; R 2 and R 3 each independently represent a hydrogen atom, a halogeno group or the like; Ar represents an unsubstituted or substituted C6-10 aryl group or the like) or a salt thereof, and a harful organism control agent including thereof.
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公开(公告)号:EP3369732B1
公开(公告)日:2021-05-26
申请号:EP18163765.3
申请日:2010-10-27
发明人: WOHLFAHRT, Gerd , TÖRMÄKANGAS, Olli , KARJALAINEN, Arja , KNUUTTILA, Pia , HOLM, Patrik , RASKU, Sirpa , VESALAINEN, Anniina , SALO, Harri , HÖGLUND, Lisa
IPC分类号: C07D403/12 , C07D401/14 , C07D405/14 , C07D413/14 , C07D401/12 , C07D231/12 , C07D471/12 , C07D487/04 , C07D513/04
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公开(公告)号:EP3812372A2
公开(公告)日:2021-04-28
申请号:EP20198210.5
申请日:2007-12-21
发明人: BERNIAC, Joel , VERMA, Atul K.
IPC分类号: C07D207/50 , C07D231/12 , C07D239/20 , C07D241/12 , C07D261/02 , C07D261/04 , C07D263/32 , C07D265/02 , C07C237/26 , A61K31/65 , A61P31/00 , A61P31/04 , A61P31/12 , A61P33/00 , A61P33/06
摘要: The present invention relates to tetracycline derivatives, and in particular to sancycline derivatives substituted at their 7-position by a five-membered heterocyclic ring, for use in the treatment of bacterial, viral and/or parasitic infections, such as e.g. malaria, and/or inflammatory diseases.
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公开(公告)号:EP3805205A1
公开(公告)日:2021-04-14
申请号:EP20204677.7
申请日:2014-03-14
申请人: Japan Tobacco Inc.
发明人: MOTOMURA, Takahisa , SHOMI, Gakujun
IPC分类号: C07D231/12 , A61K31/415 , A61P3/00 , A61P3/04 , A61P3/10 , A61P9/04 , A61P9/10 , A61P11/00 , A61P13/12 , A61P25/00 , A61P27/02 , A61P27/12 , A61P43/00
摘要: The present invention relates to a combination drug comprising (a) compound represented by the formula [I]:
wherein n is 1 or 2, or a pharmaceutically acceptable salt thereof; and
(b) at least one other medicament effective for the prophylaxis or treatment of a disease selected from the group consisting of diabetes such as (i) type 1 diabetes or (ii) type 2 diabetes, insulin resistance syndrome, metabolic syndrome, hyperglycemia, hyperlactacidemia, diabetic complications such as (i) diabetic neuropathy, (ii) diabetic retinopathy, (iii) diabetic nephropathy or (iii) cataract, cardiac failure such as (i)acute cardiac failure or (ii) chronic cardiac failure, cardiomyopathy, myocardial ischemia, myocardial infarction, angina pectoris, dyslipidemia, atherosclerosis, peripheral arterial disease, intermittent claudication, chronic obstructive pulmonary disease, brain ischemia, cerebral apoplexy, mitochondrial disease, mitochondrial encephalomyopathy, cancer, pulmonary hypertension and Alzheimer disease, wherein the medicament (b) is/are administered simultaneously, separately or continuously.-
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公开(公告)号:EP3189048B1
公开(公告)日:2021-03-17
申请号:EP15766074.7
申请日:2015-09-03
发明人: BERGMAN, Ylva Elisabet , LESSENE, Romina , GANAME, Danny , FOITZIK, Richard Charles , MORROW, Benjamin Joseph , CAMERINO, Michelle Ang , WALKER, Scott Raymond , LAGIAKOS, H. Rachel , FEUTRILL, John , STUPPLE, Paul Anthony
IPC分类号: C07D403/12 , C07D231/12 , C07D401/12 , C07D405/12 , C07C233/78 , C07D205/04 , C07D271/10 , C07D295/185 , A61K31/397 , A61K31/40 , A61K31/4245 , A61K31/435 , A61K31/4458 , A61P35/02 , A61P35/00
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公开(公告)号:EP3587406B1
公开(公告)日:2021-01-27
申请号:EP19188403.0
申请日:2014-03-11
发明人: BAIR, Kenneth W. , LANCIA, David R., Jr. , LI, Hongbin , LOCH, James , LU, Wei , MARTIN, Matthew W. , MILLAN, David S. , SCHILLER, Shawn E.r , TEBBE, Mark J
IPC分类号: C07D295/192 , C07D215/14 , C07D231/12 , C07D217/16 , C07D231/56 , C07D401/04 , C07D403/04 , C07D235/08 , C07D405/12 , C07D413/12 , C07D417/04 , A61K31/495 , A61K31/496 , A61K31/4965 , A61K31/497 , A61K31/4985 , A61K31/5025 , A61K31/506 , A61K45/06 , A61P35/00
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公开(公告)号:EP3762367A1
公开(公告)日:2021-01-13
申请号:EP19717141.6
申请日:2019-03-04
申请人: PI Industries Ltd.
发明人: ADHAV, Nilesh Bharat , PAWAR, Rajesh , YUVARAJ, J. , BHUJADE, Paras Raybhan , NAIK, Maruti N , POTLAPALLY, Dr Rajender Kumar , GUMME, Sachin Nagnath , AUTKAR, Santosh Shridhar , GARG, Ruchi , VENKATESHA, Hagalavadi M , KLAUSENER, Alexander G.M.
IPC分类号: C07D231/12 , A01N43/56 , A01N43/653 , A01N43/76 , A01N43/80 , A01N43/82 , C07D401/12 , C07D413/12 , C07D261/08 , C07D263/32 , C07D263/34 , C07D271/06 , C07D271/10 , A01P3/00
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公开(公告)号:EP3759097A1
公开(公告)日:2021-01-06
申请号:EP19708824.8
申请日:2019-02-28
申请人: BASF SE
发明人: NESVADBA, Peter , CUNNINGHAM, Allan F. , HINDALEKAR, Shrirang , NAVE, Barbara , POTHI, Tejas , WALLQUIST, Olof , WISSEMEIER, Alexander
IPC分类号: C07D403/12 , A01N43/56 , A01N43/58 , C05C3/00 , C05G3/08 , C07D231/12 , C07D231/18 , C07D231/20 , C07D231/54 , C07D231/56 , C07D401/04 , C07D403/04 , C07D471/04
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公开(公告)号:EP3312161B1
公开(公告)日:2020-11-04
申请号:EP16810995.7
申请日:2016-06-15
发明人: SHAO, Hongming , HE, Renbao , JIN, Yizhong , WANG, Lei
IPC分类号: C07D231/12 , C07D231/14 , C07D251/30 , C07C221/00 , C07C225/14 , C07C49/255 , C07D295/125
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公开(公告)号:EP3271326B1
公开(公告)日:2020-10-28
申请号:EP16764054.9
申请日:2016-03-18
IPC分类号: C07C235/34 , C07C237/20 , C07D231/12 , C07D333/24 , C07D239/26 , C07H15/203 , C07D261/08 , C07D207/327 , C07D277/30 , C07D213/56 , C07D307/54 , A61K31/165 , A61K31/381 , A61K31/402 , A61K31/4418 , A61K31/415 , A61K31/426 , A61K31/42 , A61K31/192 , A61K31/7034 , A61P13/12
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