摘要:
A compact container having a function of uniformly discharging a cosmetic solution, which selectively discharges the contents out of the compact container using employing a push-type button and uniformly discharges the cosmetic solution by employing a disk-type panel having micro-holes. The compact container includes a container body (11), a fixing structure (15) securely mounted in the container body to define the first storage space and having a structure hole, a first case (25) mounted on the container body to cover the fixing structure and having a discharge port to discharge the contents from the container body, a disk-type panel (57) mounted on the first case and having a plurality of micro-holes to guide the contents provided through the discharge port such that the contents are discharged upward in a diffused form, a piston module (43) located in the structure hole to move between upper and lower portions of the structure hole and to open/close the discharge port, a push button (47) interposed between the fixing structure and a protective case and performing a push operation to move the piston module between the upper and lower portions of the structure hole, and a content compressing unit (41) mounted on an inner wall of the fixing structure to move the contents, which are stored in the first storage space, into the structure hole by the operation of the push button.
摘要:
The invention relates to a synergic pharmaceutical composition of mebendazole (MBDZ) with nitazoxanide (NTZX) for the treatment of human parasitosis, which significantly increases the spectrum of MBDZ against protozoa and reinforces the anthelmintic action of NTZX. Furthermore, when said pharmaceutical combination of MBDZ and NTZX is used, the same effects of the individual active substances are maintained in the systemic action of the active metabolite of NTZX, tizoxanide, and in the treatment of some systemic forms of parasitosis. In addition, the synergic pharmaceutical combination of MBDZ with NTZX achieves a larger anti-parasite spectrum, while maintaining the efficiency and safety profiles of both active substances independently. All of these effects enable the differentiation of the pharmaceutical combination from the rest of the conventional anti-parasite treatments that have more limited spectra. The invention therefore relates principally to the synergic effects of the pharmaceutical combination of MBDZ and NTZX.
摘要:
The present invention relates to novel salts of benzimidazole derivatives, preferably mesylate salt of benzimidazole derivatives which are useful intermediates in the synthesis of pure l-methyl-2-[N-[4-(N-n-hexyloxycarbonylamidino)phenyl]aminomethyl]benzimidazol-5-yl- carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide represented by the structural formula- 1 and its salts.
摘要:
The invention relates to an orally administered pharmaceutical nitazoxanide composition used for the treatment of intestinal parasitic infections, in the form of granules for suspension, in which said composition contains: (a) an immediate release fraction formed by uncoated granules or non-granular powder of nitazoxanide, and (b) a pH-dependent release fraction formed by granules of nitazoxanide coated with one or more polymers having a pH-dependent solubility.
摘要:
Disclosed are an epitope specific to hepatitis B virus (HBV) and use thereof. The disclosed epitope is a conservative position on which mutagenesis does not occur and, therefore, a composition including an antibody to the foregoing epitope or a vaccine composition including the epitope has very low possibility of causing degradation of curing efficacy due to HBV mutation, thus being very useful for HBV treatment.
摘要:
The present invention relates to a vibration module for massaging having minimized volume and thickness, and which ensures the flexibility thereof by connecting a printed-circuit board and a battery, as a single body, on a flexible support panel, the printed circuit board being provided with a vibrator and a driving part for same and a controller for the driving part. Additionally, as the vibration of the vibrator can be transmitted to the skin in the form of the vibration of the vibration module itself, the vibration can be transmitted to a comparatively wide area of the human skin compared to the size of the vibrator, and the portability of the vibration module is improved. The vibration module for massaging the skin, according to the present invention, comprises: a printed-circuit board; a vibrator disposed on the printed-circuit board; a driving part, which is mounted on the printed-circuit board, and which provides vibration power to the vibrator when power is supplied; a controller for controlling the vibration state of the vibrator by controlling the driving part; a battery for supplying the driving part and the controller with power; a support panel for connecting the printed-circuit board and the battery as a single body; a power source contact member for electrically connecting the power source terminal of the battery and the power source terminal of the driving part which is disposed on the printed-circuit board; ; and an insulation member, which is attached in the contact area between the power source terminal of the battery and the power source contact member, and which allows, when separated from the battery, a connection between the power source terminal of the battery and the power source contact member.
摘要:
Methods and systems for the use of Surface Enhanced Raman Scattering nanotags (SERS nanotags) to create homogeneous (no-wash), heterogeneous or sequence detection assay platforms. In certain embodiments the SERS nanotags are used in combination with magnetic particles. Multiplexed assay platforms are also disclosed. In certain embodiments, the assay is useful for clinical proteomics. Assay platforms suitable for use within a biological matrix, for example within whole blood or serum are also disclosed. The assay formats described herein may be used to detect any analyte of interest including but not limited to the detection of cells, viruses, bacteria, proteins, DNA, RNA, or small molecules in any type of biological (animal or plant kingdom) or environmental samples including but not limited to whole blood or serum, occult samples, urine, feces, air, drinking water, phage, any organism, multicellular clumps of cells, for example, cancer tissue homogenate.
摘要:
The present invention relates to a patch which comprises the active ingredient rotigotine and is intended for transdermal delivery of the active pharmaceutical ingredient rotigotine, comprising a backing layer (1), a matrix layer (2) which comprises the active ingredient, and a removable protective sheet (4) which is intended for removal before the patch is applied to the skin, characterized in that disposed with areal coverage between the matrix layer (2) and the removable protective sheet (4) is an additional interlayer (3).