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公开(公告)号:EP2774928A4
公开(公告)日:2015-03-18
申请号:EP12840224
申请日:2012-10-12
申请人: SHIONOGI & CO
发明人: AKIYAMA TOSHIYUKI
IPC分类号: C07D498/14 , A61K31/437 , A61K31/4985 , A61K31/5365 , A61P31/18 , C07D471/22
CPC分类号: C07D498/14 , A61K31/437 , A61K31/4985 , C07D471/22
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42.N-PHENYL-N'-PHENYLSULFONYLPIPERAZINE DERIVATIVE AND METHOD FOR PRODUCING INTERMEDIATE FOR SAME 审中-公开
标题翻译: N-苯基-N'-苯磺酰基哌嗪衍生物及其制备中间体的方法公开(公告)号:EP2832729A1
公开(公告)日:2015-02-04
申请号:EP13769121.8
申请日:2013-03-29
申请人: Shionogi & Co., Ltd.
IPC分类号: C07D263/32 , C07B61/00
CPC分类号: C07D263/32
摘要: The present invention provides the salt and the crystal thereof of 2-(oxazole-2-yl)phenol derivative which are the intermediate in the process of producing N-phenyl-N'-phenylsulfonyl piperazine derivative, and the process of producing the salt as well as the process of producing N-phenyl-N'-phenylsulfonyl piperazine derivative through the salt.
A method of producing the salt and the crystal thereof of the compound represented by Formula(I):
wherein X is halogen;
and the process of producing the salt as well as the process of producing N-phenyl-N'-phenylsulfonyl piperazine derivative through the salt.摘要翻译: 本发明提供作为制备N-苯基-N'-苯磺酰基哌嗪衍生物的方法中的中间体2-(恶唑-2-基)苯酚衍生物的盐及其晶体,以及将该盐制备为 以及通过盐制备N-苯基-N'-苯磺酰基哌嗪衍生物的方法。 由式(I)表示的化合物的盐及其晶体的制备方法:其中X是卤素; 以及生产盐的方法以及通过盐生产N-苯基-N'-苯磺酰基哌嗪衍生物的方法。
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公开(公告)号:EP2407537B1
公开(公告)日:2014-11-26
申请号:EP10750805.3
申请日:2010-03-09
申请人: Shionogi & Co., Ltd.
IPC分类号: A61K39/395 , A61P31/04 , C07K16/12
CPC分类号: C07K16/1214 , C07K2317/24 , C07K2317/76 , C07K2317/92
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44.PHARMACEUTICAL COMPOSITION CONTAINING OPTICALLY ACTIVE COMPOUND HAVING THROMBOPOIETIN RECEPTOR AGONIST ACTIVITY AND INTERMEDIATE THEREOF 有权
标题翻译: 与THROMBOPOIETINREZEPTORAGONISTENWIRKUNG及其中间体的积极光学连接的药物组合物公开(公告)号:EP2184279B1
公开(公告)日:2014-11-12
申请号:EP08791776.1
申请日:2008-07-29
申请人: Shionogi & Co., Ltd.
发明人: TAKAYAMA, Masami , KUROSE, Noriyuki
IPC分类号: C07D277/20 , A61K31/426 , A61P1/18 , A61P7/00 , A61P7/06 , A61P43/00 , C07D277/46
CPC分类号: C07D277/38 , C07D277/20 , C07D277/46
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公开(公告)号:EP2763539A1
公开(公告)日:2014-08-13
申请号:EP12838132.4
申请日:2012-10-04
IPC分类号: A01N57/00
CPC分类号: C07D501/60 , A61K31/546 , C07D501/56 , Y02A50/473 , Y02A50/481
摘要: The present invention relates to cephalosporin antibacterial compounds of Formula (I): or corresponding pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods for bacterial infections, especially those caused by gram-negative bacteria.
摘要翻译: 本发明涉及式(I)的头孢菌素抗菌化合物:其相应的药学上可接受的盐,相应的药物组合物,用于细菌感染的化合物制备和治疗方法,尤其是由革兰氏阴性细菌引起的那些。
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公开(公告)号:EP2009012B1
公开(公告)日:2014-06-25
申请号:EP07740496.0
申请日:2007-03-30
IPC分类号: C07D413/10 , A61K31/55 , A61K31/553 , A61P31/04 , C07D413/14 , C07D417/14 , C07D471/14
CPC分类号: C07D273/06 , C07D255/02 , C07D413/10 , C07D413/14 , C07D417/14 , C07D471/14 , Y02P20/55
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47.PROCESS FOR PRODUCING 1-OXACEPHALOSPORIN-7ALPHA-METHOXY-3-CHLOROMETHYL DERIVATIVE 有权
标题翻译: 用于生产1- OXACEPHALOSPORIN-7alpha甲氧基-3-氯衍生物公开(公告)号:EP1767538B1
公开(公告)日:2014-05-07
申请号:EP05734618.1
申请日:2005-04-20
申请人: Shionogi Co., Ltd.
IPC分类号: C07D505/06 , C07D505/18
CPC分类号: C07D505/00 , Y02P20/55
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公开(公告)号:EP1942105B1
公开(公告)日:2014-04-16
申请号:EP06822035.9
申请日:2006-10-23
申请人: Shionogi Co., Ltd.
发明人: KOBAYASHI, Naotake , UEDA, Kazuo , ITOH, Naohiro , SUZUKI, Shinji , SAKAGUCHI, Gaku , KATO, Akira , YUKIMASA, Akira , HORI, Akihiro , KORIYAMA, Yuji , HARAGUCHI, Hidekazu , YASUI, Ken , KANDA, Yasuhiko
IPC分类号: C07D239/14 , A61K31/426 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/54 , A61K31/541 , A61K31/5415 , A61K31/55 , A61K31/551 , A61K31/554 , A61P25/28 , A61P43/00 , C07D239/24 , C07D265/08 , C07D277/18 , C07D279/06 , C07D279/08 , C07D281/02 , C07D405/04
CPC分类号: C07D417/14 , A61K9/0019 , A61K9/1623 , A61K9/2018 , A61K31/426 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/54 , A61K31/541 , A61K31/5415 , A61K31/55 , A61K31/551 , A61K31/554 , C07D239/14 , C07D239/24 , C07D239/42 , C07D265/08 , C07D277/18 , C07D279/06 , C07D279/08 , C07D279/12 , C07D281/02 , C07D405/04 , C07D405/10 , C07D417/04 , C07D417/10 , C07D417/12 , C07D471/04
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49.TRIAZINE DERIVATIVES AS P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONISTS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM 有权
标题翻译: 三嗪衍生物AS P2X3和/或P2X 2/3 / 3受体拮抗剂和药物组合物包含此公开(公告)号:EP2399910B1
公开(公告)日:2014-04-02
申请号:EP10741243.9
申请日:2010-02-10
申请人: Shionogi & Co., Ltd.
发明人: KAI, Hiroyuki , KAMEYAMA, Takayuki , HASEGAWA, Tsuyoshi , OOHARA, Miho , TADA, Yukio , ENDOH, Takeshi
IPC分类号: C07D251/46 , A61K31/53 , A61K31/5377 , A61P13/08 , A61P13/10 , A61P21/00 , A61P25/02 , A61P25/06 , A61P25/08 , A61P29/00 , C07D251/52 , C07D401/06 , C07D401/12
CPC分类号: C07D251/46 , C07D251/16 , C07D251/44 , C07D251/52 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/12
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公开(公告)号:EP2397477B1
公开(公告)日:2014-03-05
申请号:EP11178018.5
申请日:2008-01-15
IPC分类号: C07D401/04 , C07D451/14 , C07D471/04 , C07D471/08 , A61K31/498 , A61P25/04
CPC分类号: C07D401/04 , C07D451/14 , C07D471/04 , C07D471/08
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