ENDOVASCULAR STENT GRAFT ASSEMBLY AND DELIVERY DEVICE
    42.
    发明公开
    ENDOVASCULAR STENT GRAFT ASSEMBLY AND DELIVERY DEVICE 有权
    EINFÜHRVORRICHTUNG的ENDOVASKULÄRESTENTGRAFTANORDNUNG

    公开(公告)号:EP3017790A2

    公开(公告)日:2016-05-11

    申请号:EP15275213.5

    申请日:2015-10-08

    摘要: A pre-loaded delivery device (2) that facilitates accurate placement of a stent graft assembly (6) in the aorta is disclosed. A stent graft (6) is carried on the delivery device (2) and held in a pre-deployment configuration by a sheath (10). A split (13) in the sheath (10) facilitates the pre-cannulation of one or more branch arteries extending from the aorta before the stent graft (6) is fully released in the aorta. The stent graft (6) comprises a tubular body (32) having at least one scalloped fenestration (44) formed in one end of the graft material and at least one fenestration (42) formed in the graft material of the main tubular body (32). A helical internal side branch (56) extends from the fenestration (42) within the lumen of the main tubular body. The helical side branch (56) is configured to curve at least partially around the scalloped fenestration (44). The assembly further comprises a connection stent graft (54) extending from the fenestration (42) into a branch vessel.

    摘要翻译: 公开了一种促进支架移植组件(6)精确放置在主动脉中的预加载递送装置(2)。 支架移植物(6)承载在输送装置(2)上,并通过护套(10)保持在预部署构型中。 在护套(10)内的裂缝(13)有助于在支架移植物(6)完全释放到主动脉之前从主动脉延伸的一个或多个分支动脉的预插管。 支架移植物(6)包括管状体(32),其具有形成在移植材料的一端中的至少一个扇形开窗(44)和形成在主管状体(32)的移植材料中的至少一个开窗(42) )。 螺旋内侧分支(56)从主管体的内腔中的开窗(42)延伸。 螺旋侧分支(56)构造成至少部分地围绕扇形开窗(44)弯曲。 组件还包括从开窗(42)延伸到分支容器中的连接支架移植物(54)。

    BRANCH VESSEL PROTHESIS
    44.
    发明公开
    BRANCH VESSEL PROTHESIS 审中-公开
    GEFÄSSVERZWEIGUNGSPROTHESE

    公开(公告)号:EP3005980A1

    公开(公告)日:2016-04-13

    申请号:EP15195989.7

    申请日:2012-04-27

    发明人: GREENBERG, Roy K.

    IPC分类号: A61F2/07

    摘要: In a branch vessel prosthesis (20) comprising a graft (30), a stent (46) coupled to the proximal region of the graft, where the proximal region of the graft includes a generally straight configuration in an expanded deployed state that is substantially parallel to a longitudinal axis of a main vessel; and a stent (66) coupled to the distal region of the graft, where the distal region of the graft includes a generally straight configuration in the expanded deployed state that is substantially parallel to a branch vessel, there is provided an expansion member (55) coupled to the central region (50) of the graft, where the expansion member comprises a resilient pre-formed material that promotes a curvature of the central region in the expanded deployed state.

    摘要翻译: 在包括移植物(30)的分支血管假体(20)中,支架(46)联接到移植物的近侧区域,其中移植物的近侧区域包括基本平行的展开展开状态的大致直的构型 到主容器的纵向轴线; 以及联接到所述移植物的远侧区域的支架(66),其中所述移植物的远侧区域包括基本上平行于分支血管的扩张展开状态中的大致直的构型,设置有膨胀构件(55) 耦合到移植物的中心区域(50),其中膨胀构件包括弹性预成形材料,其在扩张展开状态下促进中心区域的曲率。

    SDF-1 DELIVERY FOR TREATING ISCHEMIC TISSUE
    47.
    发明公开
    SDF-1 DELIVERY FOR TREATING ISCHEMIC TISSUE 审中-公开
    SDF-1给药治疗缺血性组织

    公开(公告)号:EP2970941A1

    公开(公告)日:2016-01-20

    申请号:EP14762452.2

    申请日:2014-03-15

    IPC分类号: C12N15/00 A61K48/00 C07H21/04

    CPC分类号: C07K14/522 A61K48/005

    摘要: Provided are methods of treating a cardiomyopathy in a subject by administering directly to, or expressing locally in, a weakened, ischemic, and/or peri-infarct region of myocardial tissue of the subject an amount of stromal-cell derived factor-1 (SDF-1 ) effective to cause functional improvement in at least one of the following parameters: left ventricular volume, left ventricular area, left ventricular dimension, cardiac function, 6-minute walk test, or New York Heart Association (NYHA) functional classification. Also provided are methods of treating critical limb ischemia in a subject by administering a DNA plasmid encoding human SDF-1 by direct injection into the affected limb.

    SYSTEM AND METHOD FOR POST-OPERATIVE LEAK DETECTION
    48.
    发明公开
    SYSTEM AND METHOD FOR POST-OPERATIVE LEAK DETECTION 审中-公开
    系统和检测方法的术后LEAKS

    公开(公告)号:EP2967342A1

    公开(公告)日:2016-01-20

    申请号:EP14732456.0

    申请日:2014-03-14

    发明人: SCHAUER, Philip

    IPC分类号: A61B5/00 A61B5/145 A61B5/1473

    摘要: The present invention relates a system that can detect a post-operative leak and a related method of use. An amylase detector that includes a sensor can detect a presence of amylase in a fluid secretion from an abdominal organ in a patient's body. The presence of amylase is indicative of the post-operative leak because, while amylase is common in the digestive tract, amylase is not normally found in the abdominal cavity. The amylase detector can alert a monitoring device external to the patient's body of the presence of amylase in the fluid secretion.