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    METHODS AND COMPOSITIONS TO IMPROVE THE NUTRITIONAL VALUE OF LIGNOCELLULOSIC BIOMASS
    45.
    发明公开
    METHODS AND COMPOSITIONS TO IMPROVE THE NUTRITIONAL VALUE OF LIGNOCELLULOSIC BIOMASS 审中-公开
    VERFAHREN UND ZUSAMMENSETZUNGEN ZUR VERBESSERUNG DESNÄHRWERTESVON LIGNOCELLULOSEBIOMASSE

    公开(公告)号：EP3013155A1

    公开(公告)日：2016-05-04

    申请号：EP14732167.3

    申请日：2014-06-19

    申请人： Dupont Nutrition Biosciences ApS

    发明人： ROMERO MILLÁN, Luis Fernando ,  YU, Shukun ,  WALSH, Maria ,  LANTZ, Suzanne ,  MITCHINSON, Colin ,  BOWER, Ben ,  ARENT, Susan

    IPC分类号： A23K10/10 ,  A23K20/189 ,  A23K10/32

    CPC分类号： A23K10/14 ,  A23K10/10 ,  A23K10/32 ,  C12Y302/01004 ,  C12Y302/01008 ,  C12Y302/01021 ,  Y02P60/877

    摘要： The present invention relates to a method of preparing a feed additive composition comprising: (a) physically and/or chemically and/or biologically pre-treating lignocellulosic biomass, (b) admixing the physically and/or chemically and/or biologically pre-treated lignocellulosic biomass with an enzyme composition, wherein the enzyme composition comprises at least the following activities: endoglucanase activity, β-glucosidase activity and endoxylanase activity and wherein the enzyme composition comprises no, or substantially no, β-xylosidase activity and/or no, or substantially no α-L- arabinofuranosidase activity, (c) incubating same for at least about 3-120 hours, (d) and optionally drying and/or optionally packaging.

    摘要翻译： 本发明涉及一种制备饲料添加剂组合物的方法，包括：（a）物理和/或化学和/或生物预处理木质纤维素生物质，（b）将物理和/或化学和/或生物学预处理 具有酶组成的木质纤维素生物质，其中所述酶组合物至少包含以下活性：内切葡聚糖酶活性，葡萄糖苷酶活性和内切木聚糖酶活性，并且其中所述酶组合物不包含或基本上不含β-脱氧核苷酸酶活性和/或不 ，或基本上没有α-L-阿拉伯呋喃糖苷酶活性，（c）将其孵育至少约3-120小时，（d）和任选地干燥和/或任选包装。

    VETERINARY PHARMACEUTICAL COMPOSITION AND METHOD (ALTERNATIVES) FOR THE PROPHYLAXIS AND TREATMENT OF DISEASES OF THE GASTROINTESTINAL TRACT AND INTOXICATIONS OF DIVERSE ETIOLOGY IN ANIMALS
    49.
    发明公开
    VETERINARY PHARMACEUTICAL COMPOSITION AND METHOD (ALTERNATIVES) FOR THE PROPHYLAXIS AND TREATMENT OF DISEASES OF THE GASTROINTESTINAL TRACT AND INTOXICATIONS OF DIVERSE ETIOLOGY IN ANIMALS 审中-公开
    动物医疗药物组合物的方法（备选）对胃道疾病和各种病因学动物中毒的预防和治疗

    公开(公告)号：EP2481413A1

    公开(公告)日：2012-08-01

    申请号：EP10819101.6

    申请日：2010-09-21

    申请人： Dikovskiy, Aleksander Vladimirovich

    发明人： TRETYAKOV, S rg i Vikt r vi h ,  TURCHEV, l g l ks ndr vi h

    IPC分类号： A61K31/7016 ,  A61K31/702 ,  A61K36/00 ,  A61P1/00

    CPC分类号： A61K31/702 ,  A23K10/32 ,  A23K20/163 ,  A23K50/10 ,  A23K50/30 ,  A23K50/75 ,  A61K31/7016 ,  A61K45/06 ,  A61K2300/00

    摘要： A veternary pharmaceutical composition for treating diseases of the gastrointestinal tract and intoxications of diverse etiology in animals comprises, as the active component, hydrolyzed lignin and a prebiotic from the following group: lactulose, fructooligosaccharides, galacto-saccharides and inulin, and is in a form suitable for use in the composition of a mixture with combined feed, with a lignin content of from 30 to 95 % by mass, in the form of powder of granules. The method for the prophylaxis and treatment of intoxication of diverse etiology, including mycotoxicoses, in animals, including birds, envisages that the animal will receive the above-mentioned veterinary pharmaceutical composition mixed with feed in a dosage of from 2 to 4.5 kg of the preparation per ton of combined feed, proportional to the content of mycotoxins in the combined feed. The method for the prophylaxis and treatment of diseases of the gastrointestinal tract, including dyspepsia, gastroenteritis, enteritis, colitis, hepatitis, and hepato-dystrophy, including in a toxic form, in animals, including cattle and pigs, envisages that the animal will receive the veterinary pharmaceutical composition according to claim 1 30 ± 10 minutes prior to feeding, perorally individually or in a group method with water for watering or with the feed, 1 to 2 times per day in a dosage of from 0.2 to 0.3 g/kg of the mass of the animal. This ensures an increase in the effectiveness of the treatment and elimination of the above-mentioned defects in the use of hydrolyzed lignin, activated carbon and other generally known sorbents. At the same time, the joint use of lignin with a prebiotic as a means for the prophylaxis and treatment of animals makes it possible to produce a result in the form of a set of positive effects: minimization of side effects from the use of a sorbent; restoration of homeostasis in the gastrointestinal tract; and normalization of the metabolism indices, this finally resulting in a qualitative increase in the zootechnical and economic indices of animal husbandry.

    摘要翻译： 用于治疗胃肠道的疾病和动物的各种病因的中毒甲veternary药物组合物包含作为活性组分，水解木质素，然后从以下组的益生元：乳果糖，低聚果糖，低聚半乳糖糖类和菊粉，并是在一种形式 适合用于与组合进料的混合物的组合物中使用，具有从30至95％的木质素含量按质量计，以颗粒的粉末的形式。 为不同的病因，包括真菌中毒，在动物，包括鸟类的中毒的预防和治疗的方法中，设想并动物将接受与进料混合上述兽医药物组合物中的从2〜4.5千克制剂的剂量 每吨饲料组合，正比于霉菌毒素的组合进料的含量。 对于胃肠道疾病，包括消化不良，肠胃炎，肠炎，结肠炎，肝炎和肝营养不良，包括毒性形式，在动物，包括牛和猪的预防和治疗的方法中，设想并动物将接受 兽用药物组合物，NACH请求权1 30±10分钟，然后到喂食，经口单独地或在0.2至0.3g的剂量与水的分组方法浇水或与进料，每天1至2次/公斤的 大规模的动物。 这确保在使用水解木质素，活性炭和其它基因的反弹已知吸附剂的治疗和消除上述缺陷的有效性增加。 在在Sametime，联合使用的木质素与益生元作为用于预防和治疗动物的一种方法使得有可能在一组积极效果的形式产生结果：从使用的吸附剂的副作用最小化 ; 在胃肠道内稳态恢复; 和代谢指标的正常化，这最终导致畜牧学和畜牧业的经济指标质的提高。