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公开(公告)号：EP1206545A1
公开(公告)日：2002-05-22
申请号：EP00949429.5
申请日：2000-07-31
IPC分类号： C12N15/31 , C07K14/21 , C07K16/12 , A61K39/02 , A61K39/395 , A61K48/00 , G01N33/569
CPC分类号： C07K14/212 , A61K39/00 , A61K48/00
摘要： The invention provides BASB116 polypeptides and polynucleotides encoding BASB116 polypeptides and methods for producing such polypeptides by recombinant tehniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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42.发明公开IMMUNOGENIC POLYPEPTIDE DERIVED FROM MORAXELLA CATARRHALIS AND USES THEREOF 审中-公开免疫原性多肽OFF卡他莫拉菌及其用途
公开(公告)号：EP1204751A2
公开(公告)日：2002-05-15
申请号：EP00956337.0
申请日：2000-07-27
CPC分类号： C07K14/212 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K2319/00
摘要： The invention provides BASB127 polypeptides and polynucleotides encoding BASB127 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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公开(公告)号：EP1196591A1
公开(公告)日：2002-04-17
申请号：EP00947873.6
申请日：2000-06-23
CPC分类号： C07K14/212 , A61K39/00 , A61K48/00 , C07K2319/00
摘要： The invention provides BASB112 polypeptides and polynucleotides encoding BASB112 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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44.发明公开CLONING OF BASB110 ANTIGEN FROM MORAXELLA (BRANHAMELLA) CATARRHALIS 审中-公开KLONIERUNG DES MORAXELLA（BRANHAMELLA）CATARRHALIS ANTIGENS BASB110
公开(公告)号：EP1196589A1
公开(公告)日：2002-04-17
申请号：EP00945812.6
申请日：2000-06-23
CPC分类号： C07K14/212 , A61K2039/57 , C07K2319/00
摘要： The invention provides BASB110 polypeptides and polynucleotides encoding BASB110 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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公开(公告)号：EP1185658A2
公开(公告)日：2002-03-13
申请号：EP00927226.1
申请日：2000-05-18
CPC分类号： C07K14/212 , A61K39/00 , A61K2039/505 , A61K2039/53
摘要： The invention provides BASB103, BASB104, BASB105, BASB106, BASB107 and BASB108 polypeptides and polynucleotides encoding BASB103, BASB104, BASB105, BASB106, BASB107 and BASB108 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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46.发明公开$i(MORAXELLA CATARRHALIS) PROTEIN, NUCLEIC ACID SEQUENCE AND USES THEREOF 审中-公开-i（粘膜炎莫拉菌）PrPTEIN; NUKLEINSAÜRESEQUENZ及应用
公开(公告)号：EP1117779A1
公开(公告)日：2001-07-25
申请号：EP99951716.2
申请日：1999-10-01
CPC分类号： C07K14/212 , A61K38/00 , A61K39/00 , A61K2035/11 , A61K2039/522 , A61K2039/523 , A61K2039/53 , C07K16/1214 , C07K2317/734
摘要： The invention discloses the Moraxella catarrhalis outer membrane protein polypeptide and polypeptides derived therefrom (collectively 'OMP21'), nucleotide sequences encoding said OMP21, and antibodies that specifically bind OMP21. Also disclosed are pharmaceutical compositions including prophylactic or therapeutic compositions, which may be immunogenic compositions including vaccines, comprising OMP21, antibodies thereto or nucleotides encoding same. The invention additionally discloses methods of inducing an immune response to M. catarrhalis and OMP21 in an animal, preferably a human, methods of treating and methods of diagnosing Moraxella infections in an animal, preferably a human, and kits therefor.
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公开(公告)号：EP1086229A2
公开(公告)日：2001-03-28
申请号：EP99927846.8
申请日：1999-05-31
发明人： THONNARD, Joelle
IPC分类号： C12N15/31 , C07K14/21 , C12N15/63 , C12N5/10 , C12P21/00 , A61K39/104 , C07K16/12 , G01N33/569
CPC分类号： C07K14/212 , A61K39/00
摘要： The invention provides BASB021 polypeptides and polynucleotides encoding BASB021 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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公开(公告)号：EP1086127A1
公开(公告)日：2001-03-28
申请号：EP99950345.1
申请日：1999-05-10
CPC分类号： C07K14/212 , A61K39/00
摘要： The invention provides BASB009 polypeptides and polynucleotides encoding BASB009 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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49.发明公开PROTEIN-106 POLYPEPTIDE OF THE OUTER MEMBRANE OF MORAXELLA CATARRHALIS, GENE SEQUENCE AND USES THEREOF 失效PROTEIN-106多肽卡他莫拉菌外膜，其基因序列和需求
公开(公告)号：EP0900025A4
公开(公告)日：2000-01-05
申请号：EP97926409
申请日：1997-04-28
申请人： ANTEX BIOLOG INC
发明人： TUCKER KENNETH , PLOSILA LAURA
IPC分类号： C12N15/09 , A01N63/00 , A61K39/00 , A61K39/095 , C07H21/02 , C07K14/195 , C07K14/21 , C07K16/12 , C12N15/00 , C12P21/02 , C12R1/01 , A01N65/00 , A61K39/02 , A61K39/38 , A61K39/395 , A61K39/40 , C07H21/04 , C07K16/00
CPC分类号： C07K14/212 , A61K39/00 , A61K2039/505 , C07K16/1203 , C07K16/1214 , C07K16/1217 , C07K2317/73 , C07K2317/734
摘要： A novel isolated or substantially pure OMP106 polypeptide, is an outer membrane polypeptide of Moraxella catarrhalis, and has a molecular weight of \=180-230 kD, as determined in SDS-PAGE using rabbit skeletal muscle myosin and E. coli ~b-galactosidase as the 200 kD and 116.25 kD molecular weight standards, respectively.
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公开(公告)号：EP0866803A1
公开(公告)日：1998-09-30
申请号：EP96933285.0
申请日：1996-10-11
CPC分类号： A61K39/39 , A61K39/00 , A61K2039/55505 , A61K2039/55516 , A61K2039/5555 , A61K2039/55555 , A61K2039/55577 , A61K2039/55594 , C07K14/212
摘要： An isolated and purified non-denatured transferrin receptor protein of a Moraxella strain, particularly M. catarrhalis, has an apparent molecular mass of about 80 to about 90 kDa, as determined by SDS-PAGE. The transferrin receptor protein or a fragment analog thereof is useful in diagnostic applications and immunogenic compositions, particularly for in vivo administration to a host to confer protection against disease caused by a strain of Moraxella.
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