-
1.发明公开BASB207 POLYPEPTIDES AND POLYNUCLEOTIDES FROM NONTYPEABLE HAEMOPHILUS INFLUENZAE 审中-公开BASB207多肽和多核苷酸OFF不可分型流感嗜血杆菌
公开(公告)号：EP1328541A2
公开(公告)日：2003-07-23
申请号：EP01987767.9
申请日：2001-10-16
发明人： THONNARD, Joelle
IPC分类号： C07K14/285
CPC分类号： C07K14/285 , A61K39/00 , C07K16/1242
摘要： The invention provides nontypeable Haemophilus influenzae BASB207 polypeptides and polynucleotides encoding BASB207 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses, including vaccines against bacterial infections.
-
2.发明公开
公开(公告)号：EP1254234A1
公开(公告)日：2002-11-06
申请号：EP01913816.3
申请日：2001-02-13
IPC分类号： C12N15/31 , C07K14/285 , A61K39/102
CPC分类号： C07K14/285 , A61K39/00
摘要： This invention relates to recombinant bacterial outer membrane proteins comprising one or more LB1(f) peptides from surface-exposed loop 3 of MOMP P5 of non-typeable H. influenzae. Polynucleotides encoding these recombinant proteins are also covered. The invention also relates to a method of isolating the recombinant proteins and a vaccine composition for use in the treatment of Haemophilus influenzae infection.
-
3.发明公开
公开(公告)号：EP1216302A2
公开(公告)日：2002-06-26
申请号：EP00967819.4
申请日：2000-09-26
发明人： THONNARD, Joelle
CPC分类号： C07K14/212 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K2319/00
摘要： The invention provides BASB132 polypeptides and polynucleotides encoding BASB132 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
公开(公告)号：EP1153126A1
公开(公告)日：2001-11-14
申请号：EP00903629.4
申请日：2000-01-25
发明人： THONNARD, Joelle
CPC分类号： C07K14/22 , A61K2039/52
摘要： The invention provides BASB058 polypeptides and polynucleotides from Neisseria meningitidis encoding BASB058 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
5.发明公开NEISSERIA MENINGITIDIS ANTIGENIC POLYPEPTIDES, CORRESPONDING POLYNUCLEOTIDES AND PROTECTIVE ANTIBODIES 审中-公开抗原多肽与脑膜炎奈瑟氏菌，NEVER的编码核苷酸和适当的保护性抗体
公开(公告)号：EP1147194A1
公开(公告)日：2001-10-24
申请号：EP00901585.0
申请日：2000-01-19
发明人： THONNARD, Joelle
IPC分类号： C12N15/31 , C07K14/22 , A61K39/095 , C07K16/12 , G01N33/569
CPC分类号： C07K16/1217 , A61K39/00 , A61K2039/53 , C07K14/22 , G01N33/56911 , G01N2333/22
摘要： The invention provides Neisseria meningitidis BASB056 polypeptides and polynucleotides encoding BASB056 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses thereof.
-
公开(公告)号：EP1086229A2
公开(公告)日：2001-03-28
申请号：EP99927846.8
申请日：1999-05-31
发明人： THONNARD, Joelle
IPC分类号： C12N15/31 , C07K14/21 , C12N15/63 , C12N5/10 , C12P21/00 , A61K39/104 , C07K16/12 , G01N33/569
CPC分类号： C07K14/212 , A61K39/00
摘要： The invention provides BASB021 polypeptides and polynucleotides encoding BASB021 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
7.发明授权HYPERBLEBBING BACTERIAL STRAINS AND USE THEREOF FOR PRODUCTION OF VACCINES 有权“HYPERBLEBBING”细菌菌株及其用于疫苗生产
公开(公告)号：EP1357938B8
公开(公告)日：2009-09-09
申请号：EP02700219.5
申请日：2002-02-08
发明人： BERTHET, Francois-Xavier Jacques , DENOEL, PHilippe , NEYT, Cecile Anne , POOLMAN, Jan , THONNARD, Joelle
IPC分类号： A61K39/095
CPC分类号： C07K14/285 , A61K2039/52 , C07K14/195 , C07K14/22 , C12N1/20 , Y02A50/484
摘要： The present invention relates to the field of, engineered Gram-negative bacterial strains that have outer-membrane vesicle shedding properties, and vaccine compositions comprising these bacteria or vesicles. The present invention provides a hyperblebbing Gram-negative bacterium which has been genetically modified by either or both processes selected from a group consisting of: down- regulation of expression of one or more tol genes; and mutation of one or more gene(s) encoding a protein comprising a peptidoglycan-associated site to attenuate the peptidoglycan-binding activity of the protein(s).
-
公开(公告)号：EP1212426A1
公开(公告)日：2002-06-12
申请号：EP00964177.0
申请日：2000-09-14
发明人： THONNARD, Joelle
CPC分类号： C07K14/212 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K16/1214 , C07K2319/00
摘要： The invention provides BASB109 polypeptides and polynucleotides encoding BASB109 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
公开(公告)号：EP1105493A1
公开(公告)日：2001-06-13
申请号：EP99944404.5
申请日：1999-08-13
发明人： THONNARD, Joelle
IPC分类号： C12N15/31 , C07K14/22 , A61K39/095 , C07K16/12 , G01N33/53 , A61K39/395
摘要： The invention provides BASB024 polypeptides and polynucleotides encoding BASB024 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
10.发明公开
公开(公告)号：EP1206549A1
公开(公告)日：2002-05-22
申请号：EP00958324.6
申请日：2000-07-31
发明人： THONNARD, Joelle
IPC分类号： C12N15/31 , C07K14/21 , C07K16/12 , A61K39/02 , A61K39/395 , A61K48/00 , G01N33/569
CPC分类号： C07K14/212 , A61K39/00 , A61K48/00
摘要： The invention provides BASB119 polypeptides and polynucleotides encoding BASB119 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.015 秒)
