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公开(公告)号：EP2325161B1
公开(公告)日：2018-07-25
申请号：EP09810067.0
申请日：2009-08-24
发明人： ISHIDA, Hajime , HIROTA, Masaji
IPC分类号： C07C67/22 , C07C69/734 , C07C257/06
CPC分类号： C07C67/20 , C07C257/06 , C07C69/734 , C07C69/732
摘要： Disclosed is a method for producing a compound represented by Formula (4), the method including Step I of adding a solution in which hydrogen chloride is dissolved in an alcohol, to a mixture containing an organic solvent and a compound represented by Formula (1), and Step II of mixing a compound obtained in Step I, represented by Formula (3), with water.
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42.发明授权
公开(公告)号：EP3013785B1
公开(公告)日：2018-04-25
申请号：EP14738422.6
申请日：2014-06-20
IPC分类号： C07C67/22 , C07C255/46 , C07C67/343 , C07C51/08 , C07C253/30 , C07C51/353
CPC分类号： C07C253/30 , C07C51/353 , C07C67/343 , C07C2601/02 , C07C69/743 , C07C255/46
摘要： The present invention relates to a process for the cyclopropanation with ethylene carbonate or ethylene sulfate of a compound of formula (II): wherein G is -CN or -COOR in which R is a C 1 -C 4 straight or branched alkyl X and Y are independently selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, R 1 O- and R 1 S- wherein R 1 is C1-C4 straight or branched alkyl chain.
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43.发明授权Process for recovering valued compounds from a stream derived from purification of methyl methacrylate 有权一种用于从甲基丙烯酸甲酯的纯化的流中回收有价值的化合物的方法
公开(公告)号：EP2305630B1
公开(公告)日：2015-01-28
申请号：EP10171685.0
申请日：2010-08-03
发明人： Lemonds, Andrew M. , Xu, Jinsuo
IPC分类号： C07C51/06 , C07C51/44 , C07C51/48 , C07C57/04 , C07C231/24 , C07C233/09 , C07C67/22 , C07C67/20 , C07C69/54
CPC分类号： C07C51/48 , C07C51/06 , C07C51/44 , C07C67/20 , C07C67/22 , C07C231/24 , C07C57/04 , C07C69/54 , C07C233/09
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公开(公告)号：EP2061746B1
公开(公告)日：2013-08-21
申请号：EP07803845.2
申请日：2007-07-05
申请人： Rhodia Opérations
CPC分类号： C07C67/20 , C07C67/22 , C07D207/408 , C07D211/88 , C07D223/08 , C07C69/44 , C07C69/34
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公开(公告)号：EP2061746A1
公开(公告)日：2009-05-27
申请号：EP07803845.2
申请日：2007-07-05
申请人： Rhodia Opérations
CPC分类号： C07C67/20 , C07C67/22 , C07D207/408 , C07D211/88 , C07D223/08 , C07C69/44 , C07C69/34
摘要： The present invention relates to a process for the preparation of diesters from imide or dinitrile compounds. More particularly, said invention relates to a process for the preparation of diester compounds from dinitrile compounds by utilizing vapor phase hydrolysis of dinitrile compounds in the presence of alcohol for obtaining diester compounds. Still more particularly, said invention relates to a process for the preparation of diesters from branched dinitrile compounds such as methylglutaronitrile or the branched dinitrile compounds obtained as secondary products during the preparation of adiponitrile by hydrocyanation of butadiene.
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46.发明授权VERFAHREN UND ZWISCHENPRODUKTE ZUR HERSTELLUNG VON ALPHA-METHOXYIMINOCARBONSÄUREMETHYLAMIDEN 失效过程和中间产物ALPHA-METHOXYIMINOCARBONSÄUREMETHYLAMIDEN生产
公开(公告)号：EP0765304B2
公开(公告)日：2007-08-22
申请号：EP95921761.3
申请日：1995-05-26
申请人： Bayer CropScience AG
发明人： BAYER, Herbert , ISAK, Heinz , WINGERT, Horst , SAUTER, Hubert , KEIL, Michael , NETT, Markus , BENOIT, Remy , MÜLLER, Ruth
IPC分类号： C07C67/22 , C07C249/08 , C07C249/12 , C07C251/48 , C07C69/738 , C07C251/60 , C07C235/78 , C07D249/12
CPC分类号： C07D249/12 , C07C67/22 , C07C235/78 , C07C249/08 , C07C249/12 , C07C251/48 , C07C251/60 , C07C69/738
摘要： The invention concerns a method of preparing α-methoxyiminocarboxylic acid methylamides of formula (I) (X = nitro, trifluoromethyl, halogen, alkyl or alkoxy; n = 0, 1, 2, 3 or 4; Y = an organic carbon group) by the Pinner reaction of a cyanoketone of formula (II) with an alcohol, followed by reaction of the ester of formula (IV) formed in the Pinner reaction with hydroxylamine to give an oxime of formula (V), methylation of (V) to give an oxime ether of formula (VI) and subsequent reaction of (VI) with methylamine. The invention also concerns the intermediates used in the method.
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47.发明公开
公开(公告)号：EP1615877A1
公开(公告)日：2006-01-18
申请号：EP04727443.6
申请日：2004-04-14
申请人： LG Life Sciences Ltd
发明人： CHO, Sung-Wook, R & D Park, LG Life Sciences Ltd , CHANG, Jay-Hyok, R & D Park, LG Life Sciences Ltd , LEE, Kyu-Woong, R & D Park, LG Life Sciences Ltd , LEE, Ki-Kon, R & D Park, LG Life Sciences Ltd , SO, Byung-Ran, R & D Park, LG Life Sciences Ltd , SHIN, Hyun-Ik, R & D Park, LG Life Sciences Ltd
IPC分类号： C07C253/04 , C07C67/22
CPC分类号： C07C253/00 , C07B2200/07 , C07C67/22 , C07C253/16 , C07C69/675 , C07C255/12 , C07C255/15
摘要： The present invention relates to a process for preparing 4-chloro-3-hydroxybutanoic acid ester, an intermediate for preparing atorvastatin, in high purity and yield, by comprising the steps of 1) reacting epichlorohydrin of formula (2) with cyanide of formula (3) under the condition of pH ranging from 7 to 8, to form the 4-chloro-3-hydroxybutyronitrile of formula (4) and 2a) dissolving the 4-chloro-3-hydroxybutyronitrile of formula (4) in an alcoholic solvent and reacting it with hydrogen chloride, or 2b) reacting the 4-chloro-3-hydroxybutyronitrile of formula (4) in an alcoholic solvent saturated with hydrogen chloride, to form the 4-chloro-3-hydroxybutyronitrile acid ester of formula (I).
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公开(公告)号：EP0825977B1
公开(公告)日：2000-02-16
申请号：EP96919686.4
申请日：1996-05-07
发明人： FUCHS, Eberhard
IPC分类号： C07C231/06 , C07D213/803 , C07D213/82 , C07C67/22
CPC分类号： C07D213/803 , C07C67/22 , C07C231/06 , C07D213/80 , C07D213/81 , C07C69/675
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49.发明授权A method of preparing a saturated monocyclic hydrocarbon compound and an intermediate therefor 失效制备的饱和单环烃化合物的方法和中间体用于此
公开(公告)号：EP0585104B1
公开(公告)日：1997-03-19
申请号：EP93306693.8
申请日：1993-08-24
申请人： Japan Tobacco Inc.
发明人： Ebata, Takashi, c/o Japan Tobacco Inc. , Koseki, Koshi, c/o Japan Tobacco Inc. , Okano, Koji, c/o Japan Tobacco Inc. , Kawakami, Hiroshi, c/o Japan Tobacco Inc. , Matsumoto, Katsuya, c/o Japan Tobacco Inc. , Matsushita, Hajime, c/o Japan Tobacco Inc.
IPC分类号： C07C69/675 , C07C67/22 , C07D311/00 , C07C253/16 , C07D307/20 , C07D301/02 , C07D307/33 , C07C35/06 , C07C29/147
CPC分类号： C07D307/00 , C07C69/675 , Y02P20/55
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公开(公告)号：EP0075356B1
公开(公告)日：1985-07-31
申请号：EP82201115.1
申请日：1982-09-09
申请人： STAMICARBON B.V.
CPC分类号： C07C69/612
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