公开(公告)号：EP1699629B1

公开(公告)日：2010-10-06

申请号：EP04803041.5

申请日：2004-12-20

申请人： NOVO NORDISK A/S

发明人： SOERENSEN, Anne ,  SPARHOLT, Philip, Albert ,  HANSEN, Marianne, Rye

IPC分类号： B32B27/08 ,  B65D30/08

CPC分类号： B32B27/08 ,  A61J1/00 ,  B32B27/30 ,  B32B27/32 ,  B32B27/322 ,  B32B2307/412 ,  B32B2307/7265 ,  B32B2439/80 ,  C08J5/18 ,  C08J2323/02 ,  Y10S206/828 ,  Y10T428/1334 ,  Y10T428/1352

摘要： A flexible container consisting of a PCTFE monolayer, the thickness of said layer being about 40-100 m, which container is equipped with a device where the liquid can be lead out through when desired and which container is transparent, shows superior properties for storing liquid pharmaceutical compositions, especially insulin compositions containing preservatives.

公开(公告)号：EP2155348A1

公开(公告)日：2010-02-24

申请号：EP08760303.1

申请日：2008-05-30

申请人： Novo Nordisk A/S

发明人： LARSEN, Per ,  SCHOU, Ole ,  DAMTOFT, Søren ,  HOWELLS, Lotte Boe

IPC分类号： B01D15/20 ,  B01J20/32 ,  B01J20/34

CPC分类号： B01D15/203 ,  B01J20/103 ,  B01J20/283 ,  B01J20/3204 ,  B01J20/3242 ,  B01J20/3289 ,  B01J20/3425 ,  B01J20/3475 ,  B01J20/3483 ,  Y10T428/31663

摘要： The present invention relates to a process for re-coating of a silica gel material with a coating, especially re-coating of an already used or spent coated silica gel material, and the re-coated silica gel material obtainable by the process, and uses thereof.

公开(公告)号：EP1156821B1

公开(公告)日：2007-05-02

申请号：EP00906177.1

申请日：2000-02-23

申请人： NOVO NORDISK A/S

发明人： GRONDAHL, Christian

IPC分类号： A61K38/24 ,  A61K31/575 ,  A61P15/08

CPC分类号： A61K38/24 ,  A61K31/575 ,  A61K38/09 ,  A61K2300/00

摘要： In an in vitro fertilisation method, a woman is treated with a hypothalamic hormone and/or a pituitary hormone or an agonist or antagonist thereof or an active derivative thereof for a short period of time and, thereafter, using in vitro oocyte maturation egg or eggs are retrieved from the woman and are maturated using a meiosis activating compound.

公开(公告)号：EP1738896A1

公开(公告)日：2007-01-03

申请号：EP05105731.3

申请日：2005-06-28

申请人： NOVO NORDISK A/S

发明人： Sparholt, Philip Albert ,  Hansen, Lasse

IPC分类号： B32B7/02

CPC分类号： B32B27/08 ,  A61J1/00 ,  A61J1/1406 ,  B32B7/02 ,  B32B7/12 ,  B32B25/08 ,  B32B25/20 ,  B32B27/302 ,  B32B27/32 ,  B32B27/322 ,  B32B27/34 ,  B32B27/36 ,  B32B27/40 ,  B32B2309/105 ,  B32B2439/80 ,  Y10T428/1334 ,  Y10T428/266 ,  Y10T428/2817 ,  Y10T428/2826

摘要： A flexible multilayer film for forming a container defining a liquid-tight chamber for storing a liquid. The film comprises a first layer (1) and a second layer (2). The first layer (1) is a barrier layer, eg. a PCTFE layer, which is arranged inwardly of the second layer (2) as seen in a direction from the chamber of the container formed from the multilayer film. The second layer (2) is a septum layer, eg. a TPE layer, having self-sealing properties so as to seal around a hypodermic needle penetrating said film. As seen the above direction an innermost surface (5) of the film is weldable onto itself and is preferably made of a weldable layer (3) comprising PE and/or PP.

摘要翻译： 一种柔性多层膜，用于形成限定用于储存液体的液密室的容器。 膜包括第一层（1）和第二层（2）。 第一层（1）是阻挡层，例如。 PCTFE层，其在从由多层膜形成的容器的室的方向观察时，布置在第二层（2）的内侧。 第二层（2）是隔膜层，例如。 TPE层，具有自密封性质，以密封渗透所述膜的皮下注射针。 如上所述，膜的最内表面（5）可焊接到其自身上，并且优选由包含PE和/或PP的可焊接层（3）制成。

公开(公告)号：EP1663295A2

公开(公告)日：2006-06-07

申请号：EP04762796.3

申请日：2004-08-31

申请人： NOVO NORDISK A/S

发明人： SCHLEIN, Morten ,  LUDVIGSEN, Svend

IPC分类号： A61K38/26 ,  A61K9/08 ,  A61K47/18

CPC分类号： A61K38/26 ,  A61K9/0019 ,  A61K9/08 ,  A61K38/2278 ,  A61K47/10 ,  A61K47/183 ,  A61K47/20

摘要： Method for increasing the shelf-life of a pharmaceutical formulation comprising a glucagon-like peptide.

公开(公告)号：EP1641616A1

公开(公告)日：2006-04-05

申请号：EP04738937.4

申请日：2004-06-23

申请人： NOVO NORDISK A/S

发明人： MADSEN, Nils, Berg ,  NIELSEN, John, Stern

IPC分类号： B32B27/08 ,  A61J1/00 ,  B65D30/08

CPC分类号： B32B27/08 ,  A61J1/00 ,  A61J1/10 ,  A61M2207/00 ,  B32B1/02 ,  B32B1/08 ,  B32B27/28 ,  B32B27/304 ,  B32B27/32 ,  B32B2307/412 ,  B32B2307/7246 ,  B32B2323/04 ,  B32B2323/10 ,  B32B2327/12 ,  B32B2439/80 ,  Y10T428/1334 ,  Y10T428/1352

摘要： A container consisting of at least two layers, the inner layer consisting of a PE or PP film and the PCTFE layer consisting of a PCTFE film, and the thickness of the PCTFE layer being about 40-100 µm, which container is equipped with a device where the liquid can be lead out through when desired and which container is transparent, shows superior properties for storing liquid pharmaceutical compositions, especially insulin compositions containing preservatives.

公开(公告)号：EP1636189A1

公开(公告)日：2006-03-22

申请号：EP04736501.0

申请日：2004-06-10

申请人： NOVO NORDISK A/S

发明人： HANSEN, Holger, Claus ,  CORNELIS DE JONG, Johannes ,  JACOBSEN, Poul ,  EBDRUP, Soeren

IPC分类号： C07D213/75 ,  C07D213/74 ,  C07D213/80 ,  C07D213/76 ,  C07D401/12 ,  C07D401/14 ,  A61P3/06 ,  A61P3/10 ,  A61K31/496

CPC分类号： C07D213/74 ,  C07D213/65 ,  C07D213/75 ,  C07D213/76 ,  C07D213/80 ,  C07D233/54 ,  C07D401/12 ,  C07D401/14 ,  C07D405/04 ,  C07D473/34

摘要： Novel piperazines of formula (I), pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to hormone sensitive lipase. More particularly, the compounds are useful for the treatment and/or prevention of diseases and disorders in which modulation of lipolysis, such as decreased lipolysis is beneficial. (I).

公开(公告)号：EP1448786A2

公开(公告)日：2004-08-25

申请号：EP02779247.2

申请日：2002-11-15

申请人： NOVO NORDISK A/S

发明人： BOGSNES, Are ,  CHRISTIANSEN, Ingun ,  BALSCHMIDT, Per

IPC分类号： C12P21/02 ,  C07K14/62

CPC分类号： C07K14/62 ,  Y02P20/55

摘要： A preferred way of converting insulin precursors into insulin compounds is to perform an enzymatic peptide cleavage in an aqueous medium and, thereafter, without removal of the intermediate product formed, to add an amino acid ester or a peptide ester and an organic solvent so that the desired coupling takes place.

公开(公告)号：EP1315751A2

公开(公告)日：2003-06-04

申请号：EP01957793.1

申请日：2001-08-24

申请人： NOVO NORDISK A/S ,  SCHERING AKTIENGESELLSCHAFT

发明人： WAHL, Philip ,  VISSING, Henrik ,  GRONDAHL, Christian

IPC分类号： C07K14/705 ,  C07K16/28 ,  C12N15/12 ,  C12N15/11

CPC分类号： C07K14/72 ,  C07K14/705

摘要： Two receptors of meiosis activating sterols designated SAM1A and SAM1B have been identified.

公开(公告)号：EP1292324A2

公开(公告)日：2003-03-19

申请号：EP01927641.9

申请日：2001-04-30

申请人： NOVO NORDISK A/S ,  K.U. LEUVEN RESEARCH & DEVELOPMENT

发明人： VAN DEN BERGHE, Greta

IPC分类号： A61K38/28 ,  A61P25/02 ,  A61P31/00 ,  A61P9/00

CPC分类号： A61K38/28

摘要： This invention relates to a life saving medicament for critically ill patients and a method of treatment. The composition is a pharmaceutically effective amount of a blood glucose regulator which is used to control the blood glucose level.