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    DEVICE FOR MEASURING BLOOD SUGAR LEVEL AND DEVICE FOR CONTROLLING MEASUREMENT DATA
    54.
    发明公开
    DEVICE FOR MEASURING BLOOD SUGAR LEVEL AND DEVICE FOR CONTROLLING MEASUREMENT DATA 审中-公开
    VORRICHTUNG ZUR MESSUNG DES BLUTZUCKER SPIEGELS UND VORRICHTUNG ZUR MESSDATENKONTROLLE

    公开(公告)号：EP2333551A4

    公开(公告)日：2013-07-31

    申请号：EP09817685

    申请日：2009-09-24

    申请人： TERUMO CORP

    发明人： NOMURA TAKAFUMI ,  ISHIKAWA KOU ,  SUDA MASAYOSHI ,  NAKAMURA TOSHIHISA ,  MOMOKI HIDEYUKI

    IPC分类号： G06F19/00 ,  A61B5/15 ,  G01N33/66

    CPC分类号： C12Q1/006 ,  A61B5/1411 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/150786 ,  A61B5/150854 ,  A61B5/157 ,  A61B2560/0242 ,  A61B2562/08 ,  G01N33/48792 ,  G01N35/00871 ,  G01N2035/00881 ,  G06F19/3418 ,  G16H40/63

    摘要： A novel blood glucose level measuring apparatus and a novel measurement data management apparatus are provided which can carry out measurement of the blood glucose level of a plurality of patients rapidly and with certainty and can rapidly deal also with an emergency situation. The blood glucose level measuring apparatus includes patient identification means, blood glucose level measuring means, time counting means, display means, control means having a normal measurement mode in which patient identification information and a patient data table are cross-checked with each other and then, if the patient identification information is not found, measurement of the blood glucose level is inhibited and an emergency measurement mode in which carrying out of measurement of the blood glucose level is permitted without acquiring the patient identification information by the identification means.

    摘要翻译： 提供了一种新颖的血糖值测量装置和新颖的测量数据管理装置，其可以快速且可靠地进行多个患者的血糖水平的测量，并且可以快速处理紧急情况。 血糖值测量装置包括患者识别装置，血糖值测量装置，时间计数装置，显示装置，具有正常测量模式的控制装置，其中患者识别信息和患者数据表彼此交叉检查，然后 如果没有发现患者识别信息，则禁止血糖值的测量，并且允许通过识别装置获取患者识别信息而进行血糖值的测量的紧急测量模式。

    GLUCOSE DEHYDROGENASE
    57.
    发明公开
    GLUCOSE DEHYDROGENASE 审中-公开
    GLUCOSEDEHYDROGENASE

    公开(公告)号：EP2589655A1

    公开(公告)日：2013-05-08

    申请号：EP11800446.4

    申请日：2011-06-29

    申请人： Ultizyme International Ltd.

    发明人： SODE, Koji ,  MORI, Kazushige

    IPC分类号： C12N15/09 ,  C12M1/34 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/04 ,  C12Q1/32 ,  G01N27/327 ,  G01N27/416

    CPC分类号： C12N9/0006 ,  C12Q1/006

    摘要： Disclosed is a modified glucose dehydrogenases that has dramatically increased productivity in Escherichia coli and dramatically increased thermal stability, which is obtained by introducing specific amino acid mutations to glucose dehydrogenase derived from Botryotinia fuckeliana. Also disclosed is a modified glucose dehydrogenases that has dramatically increased productivity in E. coli and dramatically increased thermal stability, which is obtained by replacing two amino acid residues in glucose dehydrogenase of fungal origin with cysteine residues. The novel glucose dehydrogenase has a low reactivity to xylose.

    摘要翻译： 公开了一种修饰的葡萄糖脱氢酶，其在大肠杆菌中显着提高了生产力并且显着提高了热稳定性，这是通过将特异性氨基酸突变引入源自葡萄孢菌的葡萄糖脱氢酶而获得的。 还公开了一种修饰的葡萄糖脱氢酶，其在大肠杆菌中显着提高了生产力，并且通过用半胱氨酸残基替代真菌来源的葡萄糖脱氢酶中的两个氨基酸残基而获得了显着增加的热稳定性。 新型葡萄糖脱氢酶对木糖的反应性低。

    Biosensor, measuring instrument for biosensor, and method of quantifying substrate
    58.
    发明公开
    Biosensor, measuring instrument for biosensor, and method of quantifying substrate 有权
    Biosensor，MessinstrumentfürBiosensor und Verfahren zur Quantifizierung eines Substrats

    公开(公告)号：EP2388587A3

    公开(公告)日：2013-04-24

    申请号：EP11176154.0

    申请日：2001-11-30

    申请人： Panasonic Corporation

    发明人： Sawada, Yasuhiko ,  Matsumoto, Kazuhiro ,  Tokuno, Yoshinobu ,  Tokunaga, Hiroyuki ,  Miyazaki, Shoji

    IPC分类号： G01N33/487 ,  G01N27/327 ,  C12Q1/00

    CPC分类号： G01N27/327 ,  A61B5/1486 ,  A61B2562/0295 ,  C12Q1/001 ,  C12Q1/005 ,  C12Q1/006 ,  G01N27/26 ,  G01N27/3272 ,  G01N27/3274 ,  G01N33/48771 ,  G01N33/5438

    摘要： A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrode of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connection terminals due to a voltage application by the driving power supply.

    摘要翻译： 提供了一种测量样品液体中包含的基板的量的方法。 该方法可以减少由生物传感器引起的测量误差。 生物传感器包括绝缘板上的至少一对电极，并插入到测量装置中，该测量装置包括用于可拆卸地支撑生物传感器的支撑部分，要连接到各个电极的多个连接端子，以及驱动电源， 通过连接端子对各个电极施加电压。 只有当生物传感器沿给定方向插入到测量装置中时，生物传感器的电极之一才连接到测量装置的第一和第二连接端子，并且具有这样的结构，使得电极在第一和第二 由驱动电源施加的电压引起的连接端子。

    DEVICES AND MEHTODS FOR TESTING ANALYTES
    60.
    发明公开
    DEVICES AND MEHTODS FOR TESTING ANALYTES 审中-公开
    装置和检验方法分析物

    公开(公告)号：EP2567228A2

    公开(公告)日：2013-03-13

    申请号：EP11723997.0

    申请日：2011-05-06

    申请人： Exacsys Limited

    发明人： NOBLE, Michael ,  NELSON, Craig ,  HUMPHRIES, Mark ,  LLOYD, Carys ,  EDINGTON, David ,  RIPPETH, John

    IPC分类号： G01N33/487

    CPC分类号： G01N27/3272 ,  C12Q1/006 ,  C12Q1/54 ,  G01N27/3274 ,  G01N33/4915 ,  G01N2496/00

    摘要： A method and device are provided for measuring a level of a clinically relevant analyte (such as glucose) in a fluid (such as blood). The device includes a flow path for conducting said fluid through the device; a detection chamber arranged on said flow path; and detector means arranged to detect analyte levels in the fluid in said chamber, wherein: said detection chamber contains a predetermined amount of an analyte such that that analyte mixes with fluid in the detection chamber to form, at the detector means, a calibration sample of the fluid at a time after the arrival of the fluid in said detection chamber, and said detector means is arranged to detect a first analyte level of an unadulterated sample of the fluid at a first time which is before the formation of said calibration sample and to detect a second analyte level of said calibration sample at a second time which is after the formation of said calibration sample.