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公开(公告)号:EP3764775A1
公开(公告)日:2021-01-20
申请号:EP18711308.9
申请日:2018-03-13
申请人: Dümmen Group B.V.
发明人: KOOT, Johannes Theodorus , BÉRÉNOS, Camillo , VAN LEEUWEN-UITERDIJK, Manuela Elizabeth,Charlotte , MARIS, Paulus Cornelis
IPC分类号: A01H5/02 , A01H6/82 , A01H1/04 , C12Q1/6895
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公开(公告)号:EP3723475A1
公开(公告)日:2020-10-21
申请号:EP18887272.5
申请日:2018-12-12
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公开(公告)号:EP3695713A1
公开(公告)日:2020-08-19
申请号:EP19217255.9
申请日:2013-10-31
申请人: Cellectis , Medicago Inc.
发明人: VOYTAS, Daniel F. , MATHIS, Luc , LI, Jin , ZHANG, Feng , STODDARD, Thomas , D'AOUST, Marc-Andre
摘要: Materials and methods are provided for making plants (e.g., Nicotiana varieties) that are suitable for producing therapeutic polypeptides suitable for administration to humans and animals, particularly by making TAL effector endonuclease-induced mutations in genes encoding xylosyltransferases and fucosyltransferases.
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公开(公告)号:EP3632925A1
公开(公告)日:2020-04-08
申请号:EP18198240.6
申请日:2018-10-02
IPC分类号: C07K14/415 , C12P21/02 , C12N15/82 , A01H6/82
摘要: The present invention relates to a genetically modified plant or plant cell derived from a wild-type plant or plant cell, said wild-type plant or plant cell producing at least one serine protease comprising the motif SX 1 RGPX 2 LKPDX 3 X 4 X 5 PGX 6 SGTSMX 7 X 8 PHX 9 PX 10 WSPX 11 AX 12 X 13 SAX 14 MTT (SEQ ID No. 1), wherein X 1 is S, G or A, X 2 is a peptide consisting of 7 to 12 amino acid residues, X 3 is I or L, X 4 is T, I, L or M, X 5 is A or G, X 6 is a peptide consisting of 24 to 28 amino acid residues, X 7 is S or A, X 8 is C or A, X 9 is a peptide consisting of 12 amino acid residues, X 10 is T, E, D, K or H, X 11 is S or A, X 12 is V or I, X 13 is K or R and X 14 is I, L or M, wherein the proteolytic activity of the at least one serine protease in the genetically modified plant or plant cell is reduced compared to its activity in the wild-type plant or plant cell.
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55.
公开(公告)号:EP3629711A1
公开(公告)日:2020-04-08
申请号:EP18727798.3
申请日:2018-05-29
申请人: Vilmorin & Cie
发明人: ASHKENAZI, Varda , ROTEM, Yaniv , ECKER, Ron , NASHILEVITZ, Shai , BAROM, Naama
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公开(公告)号:EP3548612A1
公开(公告)日:2019-10-09
申请号:EP17876146.6
申请日:2017-11-29
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公开(公告)号:EP2524044B1
公开(公告)日:2024-11-13
申请号:EP11701711.1
申请日:2011-01-13
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公开(公告)号:EP4451857A1
公开(公告)日:2024-10-30
申请号:EP22908878.6
申请日:2022-12-19
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59.
公开(公告)号:EP4334440A1
公开(公告)日:2024-03-13
申请号:EP22798782.3
申请日:2022-05-04
发明人: DOMBROVSKY, Aviv , SMITH, Elisheva , LACHMAN, Oded , LURIA, Neta
IPC分类号: C12N7/04 , C12N15/113 , A01H1/00 , A01H6/82
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60.
公开(公告)号:EP4265104A1
公开(公告)日:2023-10-25
申请号:EP22739380.8
申请日:2022-01-11
发明人: WAKABAYASHI Yuki , KAKEMA Teruaki
摘要: Disclosed is a method for determining conditions for cultivating a plant body expressing a protein of interest or a peptide of interest in a 24-hour cycle in which a dark period and a light period are repeated alternately, including: a step of determining an optimum leaf temperature based on a capability to express a protein of interest or a peptide of interest; and a step of setting light and dark period leaf temperatures and light and dark period time lengths after a plant body is infected with a bacterium or a virus having a polynucleotide encoding the protein of interest or the peptide of interest so as to satisfy the following formula, the following formula being: Dark period leaf temperature (°C) × Dark period time length (hour) + Light period leaf temperature (°C) × Light period time length (hour) = Optimum leaf temperature (°C) × 24 (hour) ± 24.
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