公开(公告)号：EP0212496A1

公开(公告)日：1987-03-04

申请号：EP86110985.8

申请日：1986-08-08

申请人： ICI AMERICAS INC.

发明人： Stephen, John Fergus ,  Smith, Jerry Howard ,  Meshreki, Makram Habib

IPC分类号： C07C69/732 ,  C08K5/13 ,  C07C67/03

CPC分类号： C08K5/1345

摘要： Novel hydroxyalkylarylalkanoates of ethoxylated bisphenol A are provided which are useful as stabilizers of resins made from at least one ethylenically unsaturated monomer. A process for manufacture of these stabilizers is also provided.

公开(公告)号：EP0211630A2

公开(公告)日：1987-02-25

申请号：EP86305934.1

申请日：1986-08-01

申请人： ICI AMERICAS INC.

发明人： Gilis, Herbert

IPC分类号： C08G18/10 ,  C08G18/32 ,  C08G18/76

CPC分类号： C08G18/10 ,  C07C273/1827 ,  C08G18/5024 ,  C08G18/7818 ,  C08G2120/00

摘要： Modified organic isocynate composition containing urea and/or biuret groups, and/or salts of these groups, prepared by reacting a blocked amine composition and a polyisocyanate composition, said blocked amine composition being the reaction product of :

a. a primary and/or secondary organic amine composition having an average amine functionality of at least 0.1 and an average total active hydrogen functionality of from about 1.5 to about 10.0, and
b. a reactivity modifying agent selected from proton acids, Lewis acids, silylating agents, metallating agents and alkylating agents, and said polyisocyanate composition comprising organic polyisocyanates and/or polyisothiocyanates having a reactive isocyanate and/or isothiocyanate functionality of at least 1.0, the reaction between said blocked amine and polyisocyanate compositions being conducted so as to provide an excess of isocyanate and/or isothiocyanate groups over total active hydrogens in the blocked amine composition of at least 1.5 : 1.0.

摘要翻译： 含有尿素和/或缩二脲基团的改性有机异柠檬酸酯组合物和/或这些基团的盐，通过封闭的胺组合物和多异氰酸酯组合物反应制备，所述封闭的胺组合物是以下的反应产物：a。 具有至少0.1的平均胺官能度和约1.5至约10.0的平均总活性氢官能度的伯和/或次级有机胺组合物，以及b。 选自质子酸，路易斯酸，甲硅烷基化剂，金属化剂和烷基化剂的反应性改性剂，所述多异氰酸酯组合物包含具有至少1.0的活性异氰酸酯和/或异硫氰酸酯官能度的有机多异氰酸酯和/或多异硫氰酸酯，所述反应性改性剂 封闭的胺和多异氰酸酯组合物被进行以便提供过量的异氰酸酯和/或异硫氰酸酯基团在封闭胺组合物中的总活性氢至少为1.5:1.0。 F

公开(公告)号：EP0131897B1

公开(公告)日：1986-11-26

申请号：EP84108090.6

申请日：1984-07-10

申请人： ICI AMERICAS INC.

发明人： Kruse, Walter Max ,  Stephen, John Fergus

IPC分类号： C07C39/15 ,  C07C37/07 ,  C07C37/50

CPC分类号： C07C37/07 ,  C07C37/50 ,  C07C39/15

公开(公告)号：EP0186276A2

公开(公告)日：1986-07-02

申请号：EP85307628.9

申请日：1985-10-22

申请人： ICI AMERICAS INC.

发明人： Lynch, Matthew James

IPC分类号： A61K7/16 ,  A61K31/70

CPC分类号： A61Q11/00 ,  A61K8/4973

摘要： Oral hygiene composition containing monoalkyl and dialkyl ethers of dianhydrohexitols in the form of toothpate, mouthwash, chewing gums, confections, toothpicks and dental floss are effective in the cleaning of oral surfaces and cavities to reduce plaque accumulation caused by the action of bacteria.

摘要翻译： 含有牙膏，漱口水，口香糖，糖果，牙签和牙线形式的二脱水己糖醇的单烷基和二烷基醚的口腔卫生组合物在清洁口腔表面和腔体以减少由细菌作用引起的牙斑积聚方面是有效的。

公开(公告)号：EP0178759A1

公开(公告)日：1986-04-23

申请号：EP85305770.1

申请日：1985-08-14

申请人： ICI AMERICAS INC.

发明人： Resch, James Franklin ,  Campbell, James Boniface, Jr.

IPC分类号： C07D471/14 ,  A61K31/435

CPC分类号： C07D471/14

摘要： 57 Novel pyrazolo[3,d-b]pyridine lactams which are useful as anxiolytics are disclosed including methods of preparation, pharmaceutical compositions containing them and intermediates used in their preparation.

公开(公告)号：EP0122743A3

公开(公告)日：1986-03-26

申请号：EP84302073

申请日：1984-03-27

申请人： ICI AMERICAS INC.

发明人： Robertson, John Russell

IPC分类号： C08G18/61 ,  C08L75/04

CPC分类号： B29C33/64 ,  B29C67/246 ,  B29K2075/00 ,  B29K2083/00 ,  C08G18/61 ,  C08G2120/00 ,  C08G2125/00

摘要： Polyurethane products are made by reaction injection molding in the presence of a defined polysiloxane mold release agent which includes isocyanate reactive groups. The polysiloxane may be included in the polyol or in the isocyanate, and in the latter case, an additional silicone surfactant is present to prevent premature reaction with the isocyanate.

公开(公告)号：EP0060094B1

公开(公告)日：1986-01-22

申请号：EP82301106.9

申请日：1982-03-04

申请人： IMPERIAL CHEMICAL INDUSTRIES PLC ,  ICI AMERICAS INC.

发明人： Yellin, Tobias Oregon ,  Gilman, David John

IPC分类号： C07D213/75 ,  C07D213/76 ,  C07D239/46 ,  C07D239/42 ,  C07D249/04 ,  C07D249/06 ,  C07D277/48 ,  C07D249/14 ,  C07D231/40 ,  C07D241/20 ,  C07D251/16

CPC分类号： C07D213/76 ,  C07D231/40 ,  C07D239/42 ,  C07D239/47 ,  C07D241/20 ,  C07D249/04 ,  C07D249/06 ,  C07D249/14 ,  C07D251/16 ,  C07D277/48

公开(公告)号：EP0162464A1

公开(公告)日：1985-11-27

申请号：EP85106312.3

申请日：1985-05-22

申请人： ICI AMERICAS INC.

发明人： Hartmann, Ludwig Albert ,  Stephen, John Fergus

IPC分类号： C07D295/14 ,  C07C121/47 ,  C07C121/34 ,  C07C120/00 ,  C07D213/61 ,  C07D213/64 ,  C07D213/09

CPC分类号： C07D213/64 ,  C07C255/00 ,  C07D213/61

摘要： 3-Methyl-2-alkylamino-1-halo-1-cyano cyclobutanes are cleaved under acid conditions to form 2-halo-4-formyl-valeronitrile and 4-formyl-2-pentenonitrile which can be cyclized to form 2-substituted-5-methylpyridine derivatives. These pyridine derivatives are useful as starting materials in the manufacture of herbicides such as fluazifop- butyl.

摘要翻译： 3-甲基-2-烷基氨基-1-卤代-1-氰基环丁烷在酸性条件下裂解形成2-卤代-4-甲酰基戊腈和4-甲酰基-2-戊烯腈，其可以环化形成2-取代的 - 5-甲基吡啶衍生物。 这些吡啶衍生物可用作制造除草剂例如氟吡啶 - 丁基的原料。

公开(公告)号：EP0122012A3

公开(公告)日：1985-10-16

申请号：EP84301441

申请日：1984-03-05

申请人： ICI AMERICAS INC.

发明人： Evana, John Harold ,  Sabotta, Kenneth Thomas

IPC分类号： F42C19/10 ,  C06C07/00

CPC分类号： C06C7/00 ,  F42C19/10

摘要： An impact sensitive detonator, particularly suitable for the initiation of explosive charges in oil wells, comprises a cylindrical casing (10,110) closed at one end and open at the other end, the closed end having a thin striking surface (22,122) which deforms without rupture when struck by a rounded firing pin (60). The casing contains a primary explosive charge (50) preferably lead azide, adjacent to the closed end, a mass of finely divided refractory material (52), for example silicon carbide adjacent to the primary expolsive charge and an impact member (40, 140), extending transversely across the casing and forming with the casing a confined space for the primary explosive charge and the refractory material. The refractory material and the impact member aid the initiation of the primary explosive charge. Optionally a second charge of primary explosive may be placed on the output side of the impact member. Preferred forms of the detonator contain an output charge (56) of high explosive, for example, hexanitrostilbene between the impact member and the open end of the casing.

公开(公告)号：EP0150099A1

公开(公告)日：1985-07-31

申请号：EP85300294.7

申请日：1985-01-16

申请人： IMPERIAL CHEMICAL INDUSTRIES PLC ,  ICI AMERICAS INC.

发明人： Kirkland, Karin Monson ,  Mant, Derrick Michael

IPC分类号： C07D231/40 ,  C07D261/14 ,  C07D275/02 ,  C07D233/88 ,  C07D285/08 ,  C07D271/06 ,  C07D249/04 ,  C07D277/48 ,  C07D249/08 ,  C07D241/20 ,  C07D213/75

CPC分类号： C07D231/38 ,  C07D231/16 ,  C07D231/40

摘要： A guanidine derivative of the formula l:-
in which R 1 , R 2 , R 3 , R 4 , ring X and D are a variety of radicals defined in the specification and A is a 3-8C alkylene chain which is substituted by a hydroxy radical and into which is optionally inserted, as part of the backbone of the chain, one or two groups selected from oxygen and sulphur atoms and NH and 1-6C N-alkyl radicals; and the pharmaceutically-acceptable acid additions salts thereof. Pharmaceutical compositions and methods of manufacture are also described. The compound of the formula I is a histamine H-2 antagonist and is therefore useful in ulcer therapy.