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509 条记录 (耗时 0.022 秒)

    Method of making hydrophilic-lipophilic copolymeric powders
    61.
    发明授权
    Method of making hydrophilic-lipophilic copolymeric powders 失效
    为亲水 - 疏水共聚物粉末的制备方法。

    公开(公告)号：EP0398538B1

    公开(公告)日：1994-06-29

    申请号：EP90304712.4

    申请日：1990-05-01

    申请人： DOW CORNING CORPORATION

    发明人： Carmody, Walter James ,  Buzzelli, Anthony John

    IPC分类号： C08F2/14 ,  C08F220/28

    CPC分类号： C08F2/14

    摘要： A precipitation polymerization process for producing a macroporous crosslinked copolymeric lattice, capable of adsorbing hydrophilic and lipophilic fluids, in which process there is copolymerized at least one monounsaturated monomer and at least one polyunsaturated monomer in the presence of an organic liquid which is a solvent for the monomers but not for the copolymer, initiating the copolymerization of the monomers by means of a free radical generating catalytic compound, precipitating a copolymer in the solvent in the form of a powder and forming a dry powder by removing the solvent from the precipitated copolymeric powder. One monomer is a hydrophilic compound and the other monomer is a lipophilic compound.

    Nucleic acid probes for the detection of mycoplasma pneumoniae
    62.
    发明公开
    Nucleic acid probes for the detection of mycoplasma pneumoniae 失效
    NukleinsäureSondenfürden Nachweis von肺炎支原体（Mycoplasma Pneumoniae）。

    公开(公告)号：EP0576743A1

    公开(公告)日：1994-01-05

    申请号：EP92305126.2

    申请日：1992-06-04

    申请人： AMOCO CORPORATION

    发明人： Weisburg, William Greene ,  Pelletier, Dale Adam

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/689

    摘要： Nucleic acid probes are described for detecting the principle etiological agent of primary atypical pneumonia, Mycoplasma pneumoniae , or, optionally, Mycoplasma pneumoniae and Mycoplasma genitalium . Said probes are complementary to ribonucleic acid sequences found in these mycoplasmas and absent from other mycoplasma, other bacterial, animal, or plant genomes. As such, these probes can detect the rRNA, rDNA, or polymerase chain reaction amplification products from these mycoplasma species. This set of probes, plus the described amplification primers, circumscribe a method for detecting the etiological agents of atypical pneumonia, and for making a clinical diagnosis of this disease. This set of probes also circumscribes a method for identification of these infectious agents in culture media enrichments inoculated from clinical samples.

    摘要翻译： 描述了用于检测原发性非典型肺炎，肺炎支原体或任选的肺炎支原体和生殖支原体的主要病原体的核酸探针。 所述探针与这些支原体中发现的核糖核酸序列互补，并且不存在于其他支原体，其他细菌，动物或植物基因组中。 因此，这些探针可以检测来自这些支原体物种的rRNA，rDNA或聚合酶链反应扩增产物。 该组探针加上所述的扩增引物，限定了用于检测非典型肺炎病原体的方法，并对该病进行临床诊断。 这套探针还界定了从临床样品接种的培养基富集中鉴定这些感染因子的方法。

    2-Piperazinone compounds, their production and use
    65.
    发明公开
    2-Piperazinone compounds, their production and use 失效
    2-Piperazinonverbindungen，deren Herstellung und Verwendung。

    公开(公告)号：EP0529858A1

    公开(公告)日：1993-03-03

    申请号：EP92307292.0

    申请日：1992-08-10

    申请人： Takeda Chemical Industries, Ltd.

    发明人： Sugihara, Hirosada ,  Terashita, Zenichi

    IPC分类号： C07D241/08 ,  C07D403/06 ,  C07D403/12 ,  A61K31/495

    CPC分类号： C07D401/12 ,  A61K38/00 ,  C07D241/08 ,  C07D403/06 ,  C07D417/12 ,  C07K5/0806 ,  C07K5/0812

    摘要： The compounds of the formula

    wherein G stands for an amidino group or an optionally cyclic amino group, these being respectively optionally substituted; D stands for a spacer having 2 to 6 atomic chain optionally bonded through a hetero-atom and/or a 5- to 6-membered ring (provided that the 5- to 6-membered ring is, depending on its bonding position, counted as 2 to 3 atomic chains); R¹ stands for hydrogen, benzyl group or a lower alkyl group; R² and R³ independently stand for a residual group formed by removing -CH(NH₂)COOH from an α-amino acid, or R¹ and R² may form a 5- to 6-membered ring taken together with the adjacent N and C; X stands for hydrogen or an optionally substituted lower alkyl group; and Z stands for a group capable of forming an anion or a group convertible into an anion in a living body, or salts thereof and agents for inhibiting cell-adhesion, which are characterized by containing these compounds. The novel compounds and pharmaceutical agents are effective for prophylaxis and therapy of various diseases by controlling or inhibiting cell adhesion.

    摘要翻译： 式CHEM的化合物，其中G代表脒基或任选的环状氨基，它们分别任选被取代; D表示通过杂原子和/或5-至6-元环任意键合的具有2至6个原子键的间隔基（条件是5-至6-元环取决于其键合位置，计为 2〜3个原子链）; R 1代表氢，苄基或低级烷基; R 2和R 3独立地代表通过从α-氨基酸除去-CH（NH 2）COOH形成的残基，或R 1和R 2可以形成5-至6-元 环与相邻的N和C一起; X代表氢或任选取代的低级烷基; Z表示含有这些化合物的能够形成阴离子或可转化成生物体中的阴离子的基团或其盐和抑制细胞粘附剂的基团。 新型化合物和药剂通过控制或抑制细胞粘附而有效预防和治疗各种疾病。

    Catheter with improved fluid infusion
    66.
    发明公开
    Catheter with improved fluid infusion 失效
    Katheter mitFlüssigkeitsinfusion。

    公开(公告)号：EP0526042A1

    公开(公告)日：1993-02-03

    申请号：EP92306486.9

    申请日：1992-07-15

    申请人： Theratek International, Inc.

    发明人： Fine, Michael Jay ,  Rogers, Enora Susanne

    IPC分类号： A61B17/22

    CPC分类号： A61B17/320758 ,  A61B2090/3933

    摘要： According to the invention, there is provided an intravascular catheter (10) and thrombectomy procedure utilizing the catheter. The catheter comprises a flexible jacket (12) with a distal working head having a canalizing tip (24) rotatable at high speeds for removing thrombus from the lumen of a vessel A flexible drive assembly (26) extends through the jacket to rotate the tip and a plurality of infusion ports (31) are formed adjacent the distal end of the jacket, capable of delivering a fluid contrast media at relatively high volumetric flow rates into the lumen of the vessel to locate the site of the thrombus. The canalizing tip is then rotated at high speed to homogenize and remove the thrombus from the lumen.

    摘要翻译： 根据本发明，提供了一种使用导管的血管内导管（10）和血栓切除术。 所述导管包括柔性护套（12），其具有远端工作头，所述远端工作头具有可高速旋转的导管末端（24），用于从容器的内腔移除血栓。柔性驱动组件（26）延伸穿过护套以旋转尖端， 多个输注端口（31）形成在护套的远端附近，能够以相当高的体积流速将流体造影剂输送到容器的内腔中，以定位血栓位置。 然后将引流尖端高速旋转以均质化并从内腔中除去血栓。

    Controller for intravascular catheter system
    67.
    发明公开
    Controller for intravascular catheter system 失效
    SteuerungfürintravaskuläresKathetersystem。

    公开(公告)号：EP0524764A1

    公开(公告)日：1993-01-27

    申请号：EP92306482.8

    申请日：1992-07-15

    申请人： Theratek International, Inc.

    发明人： Sullivan, James Brian ,  Moore, Eric Rex

    IPC分类号： A61B17/22

    CPC分类号： A61B17/320758 ,  A61B2090/3933

    摘要： An intravascular catheter system has a catheter with a rotating tip and a fluid path to permit fluid to be ejected around the tip for cooling the tip. The system has an electric motor for rotating the catheter tip and a second motor for controlling the fluid flow. A control circuit sets the speed of the two motors and also monitors the speed and other parameters for operational errors. If an error is detected for either motor, the entire system, including both motors, is automatically shut down. The control circuit utilizes two processors, a main processor for system control and speed control of both motors and a slave processor for monitoring the speed of the catheter motor. The main processor provides data regarding desired speed to the catheter motor and to the slave processor and the slave processor provides signals the main processor when it detects a speed error.

    摘要翻译： 血管内导管系统具有带有旋转尖端和流体路径的导管，以允许流体围绕尖端喷射以冷却尖端。 该系统具有用于旋转导管尖端的电动马达和用于控制流体流动的第二马达。 一个控制电路设置两个电机的速度，并监控运行错误的速度和其他参数。 如果任一电机检测到错误，整个系统（包括两个电机）都将自动关闭。 控制电路使用两个处理器，一个用于系统控制的主处理器，两个电机的速度控制和用于监测导管马达的速度的从属处理器。 主处理器提供关于所需速度的数据到导管电机和从处理器，并且从处理器在检测到速度误差时向主处理器提供信号。

    Anhydrous hydrogen chloride evolving one-step process for producing siloxanes
    68.
    发明公开
    Anhydrous hydrogen chloride evolving one-step process for producing siloxanes 失效
    用于制备硅氧烷，用无水氯化氢单级过程被释放。

    公开(公告)号：EP0515082A1

    公开(公告)日：1992-11-25

    申请号：EP92304292.3

    申请日：1992-05-12

    申请人： DOW CORNING CORPORATION

    发明人： Bokerman, Gary Ned ,  Schuelke, Lawrence Michael ,  Freeburne, Steven Kerry ,  Vankoevering, Dennis Gene

    IPC分类号： C08G77/06

    CPC分类号： C08G77/06

    摘要： The instant invention is a one-step process for producing polydiorganosiloxanes (siloxanes). In the described process, a mixture comprising diorganodichlorosilane and a source of triorganosilyl groups is contacted with excess water essentially saturated with hydrogen chloride. Product siloxanes are isolated as well as saturated aqueous hydrogen chloride and anhydrous hydrogen chloride. The amount of triorganosilyl groups present in the mixture is controlled to set the degree of polymerization of product siloxanes. The isolated saturated aqueous hydrogen chloride is recycled to the process. Excess chloride generated in the process is collected as anhydrous hydrogen chloride.

    摘要翻译： 即时发明是制备聚二有机硅氧烷（硅氧烷）的单步方法。 在所描述的过程中，一种混合​​物，包含diorganodichlorosilane和三有机甲硅烷基的源极与过量的水本质上用氯化氢饱和的接触。 产物硅氧烷分离以及饱和wässrige氯化氢和无水氯化氢。 混合物中存在的三有机甲硅烷基的量被控制为设定产物的硅氧烷的聚合度。 该分离的饱和wässrige氯化氢被再循环至该过程。 过程中产生的过量的氯化物收集为无水氯化氢。

    CARBONACEOUS MATERIAL WITH HIGH ELECTROSTATIC CAPACITANCE
    70.
    发明公开
    CARBONACEOUS MATERIAL WITH HIGH ELECTROSTATIC CAPACITANCE 失效
    麻醉剂麻醉剂HOHER ELEKTROSTATISCHERKAPAZITÄT。

    公开(公告)号：EP0514545A1

    公开(公告)日：1992-11-25

    申请号：EP91903695.4

    申请日：1991-02-01

    申请人： TAKEDA CHEMICAL INDUSTRIES, LTD.

    发明人： ADACHI, Kiyoshi ,  KUROSAKI, Takeo ,  IWASHIMA, Yoshinori

    IPC分类号： C01B31/12 ,  H01G9/00

    CPC分类号： H01G9/155 ,  C01B32/348 ,  H01G9/00 ,  Y02E60/13

    摘要： A carbonaceous material prepared by heat treating an activated carbon material below 700 °C in an alkali metal hydroxide bath has a high electrostatic capacitance, and more particularly the electrostatic capacitance per unit volume thereof is several times, or even seven times or above as high as that of a conventional activated carbon for capacitors. Thus it is possible to reduce the size of a capacitor by using this material in the production of a capacitor utilizing an electric double layer.

    摘要翻译： 通过在碱金属氢氧化物浴中热处理700℃以下的活性炭材料而制备的碳质材料具有高的静电电容，更特别地，其每单位体积的静电电容是数倍，甚至高达7倍 传统的电容器用活性炭。 因此，通过在制造使用双电层的电容器中使用该材料可以减小电容器的尺寸。