公开(公告)号：EP2590985B1

公开(公告)日：2014-05-14

申请号：EP11746494.1

申请日：2011-07-08

申请人： Recordati Ireland Limited

发明人： LEONARDI, Amedeo ,  MOTTA, Gianni ,  RIVA, Carlo ,  GUARNERI, Luciano ,  GRAZIANI, Davide ,  DE TOMA, Carlo ,  KARAMFILOVA, Katia Dimitrova

IPC分类号： C07D491/10 ,  C07D498/10 ,  A61K31/438 ,  A61P13/02

CPC分类号： C07D498/10 ,  C07D491/10

公开(公告)号：EP2178858B1

公开(公告)日：2011-12-28

申请号：EP08785292.7

申请日：2008-08-01

申请人： Recordati Ireland Limited

发明人： LEONARDI, Amedeo ,  MOTTA, Gianni ,  RIVA, Carlo ,  POGGESI, Elena ,  GRAZIANI, Davide ,  LONGHI, Matteo Marco

IPC分类号： C07D401/14 ,  C07D401/06 ,  C07D401/04 ,  C07D417/06 ,  C07D417/14 ,  C07D211/70 ,  C07D409/14 ,  C07D513/04 ,  C07D413/14 ,  C07D407/14 ,  C07D471/04 ,  A61K31/4545 ,  A61P13/02

CPC分类号： C07D401/06 ,  C07D401/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/06 ,  C07D417/14 ,  C07D471/04 ,  C07D513/04

摘要： In Compounds I: Z is a group of the formula, m is 0, 1 or 2; n is 0, 1 or 2; Y is a linking group or is absent; R' is H or OH or is absent; ---- is an optional double bond; and R1, R2 and R3 are selected from a wide range of optionally substituted alkyl, cycloalkyl, aryl and heterocyclic groups. Compounds I are mGlu5 antagonists useful for the treatment of neuromuscular dysfunction of the lower urinary tract, migraine and gastroesophagael reflux disease in mammals. Preferred Compounds I are those having the formula

公开(公告)号：EP1855549B1

公开(公告)日：2011-11-23

申请号：EP06715717.2

申请日：2006-01-12

申请人： Bionutrigen Co., Ltd

发明人： BOK, Song-hae ,  LEE, Sang-ku ,  JEONG, Tae-sook ,  KIM, Eun-eai ,  CHOI, Myung-sook

IPC分类号： A23L1/30 ,  A23L1/221 ,  A23L1/314 ,  A23C9/13 ,  A23C9/152

CPC分类号： A23C9/13 ,  A23C9/152 ,  A23L13/426 ,  A23L27/10 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/2116 ,  A23V2250/2132 ,  A23V2250/21 ,  A23V2200/332 ,  A23V2250/28 ,  A23V2250/0644

摘要： The present invention is related to food for preventing fatness and hyperlipidemia, which shows prominent effects capable of providing food excellent for preventing fatness and hyperlipidemia by preparing powders or mixed powders, boiling water extracts or ethanol extracts of plants containing plenty of bioflavonoid substances, polyphenolic substances or diet fibers, and then treating meats products, processed meats products or dairy products with those preparation.

公开(公告)号：EP2326698A1

公开(公告)日：2011-06-01

申请号：EP09813484.4

申请日：2009-09-04

申请人： Lummus Technology Inc.

发明人： SKOURLIS, Thomas ,  GARTSIDE, Robert, J. ,  TRUBAC, Robert, E.

IPC分类号： C10G45/04

CPC分类号： C10G45/10 ,  B01J23/44 ,  B01J23/50 ,  C07C7/14875 ,  C10G45/04 ,  C10G70/00 ,  C10G2300/202 ,  C10G2300/4087 ,  C10L3/103 ,  C10L3/12 ,  C07C11/02

摘要： This invention relates to thioetherification processes for the removal of mercaptans in charge gas streams. In particular, the invention relates to thioetherification processes for the removal of mercaptans using a catalyst comprising palladium and silver.

公开(公告)号：EP2235465A1

公开(公告)日：2010-10-06

申请号：EP08864851.4

申请日：2008-12-18

申请人： Turbotec Products. Inc.

发明人： MIMITZ, Timothy E. ,  RAINA, Sunil ,  SCHEIDEMAN, Fred C. ,  LEWIS, Floyd J.

IPC分类号： F28D7/10

CPC分类号： F28F1/36 ,  B21C37/207 ,  F28D7/022 ,  F28D7/106 ,  F28F1/06 ,  F28F1/08 ,  F28F21/086 ,  F28F2210/06 ,  Y10T29/4935

摘要： A heat exchanger tube is disclosed herein comprising a first portion, a twisted portion, and a transition portion between the first portion and the twisted portion. The transition portion includes a reinforcing sleeve. A heat exchanger formed from the tube and a method of forming a heat exchanger tube also are disclosed. The tube is useful in making a heat exchanger configured to operate at high pressures without mechanical failure.

公开(公告)号：EP1858851A1

公开(公告)日：2007-11-28

申请号：EP05817765.0

申请日：2005-10-26

申请人： Jeil Pharmaceutical Co., Ltd.

发明人： CHOO, So Mi ,  HA, Hong Joo ,  AN, Jung Gi ,  LEE, Won Jung ,  LEE, S. G., ,  BYUN, Young Seok ,  MOON, Young Il,

IPC分类号： C07D211/90

CPC分类号： C07D211/90

摘要： The present invention relates to a method for preparing amorphous lercanidipine and, more particularly, to a method for preparing amorphous iercanidipine comprising the steps of: (1) dissolving lercanidipine in an organic solvent to form a solution; (2) forming precipitates by dropping the solution into'an organic solvent selected from the group consisting of cyclohexane, cyclopentane, hexane, and petroleum ether and stirring; (3) filtering the precipitates, washing with the organic solvent used in step 2 and vacuum drying. According to the present invention, amorphous lercanidipine having an excellent solubility and bioavailability may be prepared in high purity and yield by properly controlling major solvents and their volume ratio.

公开(公告)号：EP1855549A1

公开(公告)日：2007-11-21

申请号：EP06715717.2

申请日：2006-01-12

申请人： Bionutrigen Co., Ltd

发明人： BOK, Song-hae ,  LEE, Sang-ku ,  JEONG, Tae-sook ,  KIM, Eun-eai ,  CHOI, Myung-sook

IPC分类号： A23L1/29

CPC分类号： A23C9/13 ,  A23C9/152 ,  A23L13/426 ,  A23L27/10 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/2116 ,  A23V2250/2132 ,  A23V2250/21 ,  A23V2200/332 ,  A23V2250/28 ,  A23V2250/0644

摘要： The present invention is related to food for preventing fatness and hyperlipidemia, which shows prominent effects capable of providing food excellent for preventing fatness and hyperlipidemia by preparing powders or mixed powders, boiling water extracts or ethanol extracts of plants containing plenty of bioflavonoid substances, polyphenolic substances or diet fibers, and then treating meats products, processed meats products or dairy products with those preparation.

公开(公告)号：EP1853562A1

公开(公告)日：2007-11-14

申请号：EP06723129.0

申请日：2006-02-24

申请人： Recordati Ireland Limited ,  RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a.

发明人： LEONARDI, Amedeo ,  MOTTA, Gianni ,  BERLATI, Fabio ,  CANDIANI, Ilaria ,  CORCELLA, Francesco

IPC分类号： C07D211/90

CPC分类号： C07D211/90

摘要： The invention provides substantially pure lercanidipine free base, having a purity of at least 95 %, preferably at least about 97 %, more preferably at least about 99 %, and still more preferably at least about 99.5 %. The lercanidipine free base of the present invention is formed as an amorphous solid that is easily handled and particularly well suited to the formulation of pharmaceutical compositions.

公开(公告)号：EP1273840B1

公开(公告)日：2006-08-09

申请号：EP02076749.7

申请日：2002-05-01

申请人： KNI Incorporated

发明人： Klaymar, Edward J.

IPC分类号： F16L1/06 ,  F16L3/00

CPC分类号： F16L1/028

公开(公告)号：EP1645716A1

公开(公告)日：2006-04-12

申请号：EP04077780.7

申请日：2004-10-08

申请人： Lin, Ke-Min

发明人： Lin, Ke-Min

IPC分类号： E06B9/322

CPC分类号： E06B9/322 ,  E06B2009/3225

摘要： A winding device (1) includes a headrail (2), a winding drum (4), a pull cord (5), a carriage member (61), and a guide member (62). The winding drum (4) is mounted on the headrail (2), is operable so as to rotate relative to the headrail (2), and has threaded and smooth drum portions (41, 42). The pull cord (5) extends through the headrail (2) and is secured to the smooth drumportion (42). The carriage member (61) threadedly engages the threaded drum portion (41), and is movable along the threaded drum portion (41) when the winding drum (4) is rotated so as to wind the pull cord (5) on the smooth drum portion (42). The guide member (62) is coupled to the carriage member (61) so as to be co-movable therewith, and guides the pull cord (5) such that winding turns of the pull cord (5) on the smooth drum portion (42) are formed adjacent to one another without overlapping.

摘要翻译： 卷绕装置（1）包括头轨（2），卷绕鼓（4），拉绳（5），滑架构件（61）和引导构件（62）。 卷筒（4）安装在头架上