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公开(公告)号：EP3630139A1
公开(公告)日：2020-04-08
申请号：EP18727413.9
申请日：2018-05-22
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公开(公告)号：EP3630137A1
公开(公告)日：2020-04-08
申请号：EP18727411.3
申请日：2018-05-22
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公开(公告)号：EP3600364A1
公开(公告)日：2020-02-05
申请号：EP18735196.0
申请日：2018-06-14
发明人： MULDER, Imke Elisabeth , YUILLE, Samantha , ETTORRE, Anna , AHMED, Suaad , FOTIADOU, Parthena , URCIA, Joseph Roby Iringan , SAVIGNAC, Helene
摘要： The invention provides compositions comprising commensal bacterial strains and organic acids and the uses thereof in the treatment of diseases.
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公开(公告)号：EP3400953A1
公开(公告)日：2018-11-14
申请号：EP18165424.5
申请日：2015-12-22
发明人： KELLY, Denise
IPC分类号： A61K38/00 , A61K39/02 , A61K35/741 , C07K14/195
CPC分类号： A61K38/164 , A23L33/135 , A23L33/17 , A23L33/18 , A23V2002/00
摘要： The present invention relates to polypeptide HP, or a polynucleotide sequence encoding polypeptide HP, or a host cell comprising said polynucleotide sequence, or a host cell comprising an expression vector comprising said polynucleotide sequence, for use in the treatment and/or prevention of a disorder in a subject; wherein said disorder is an inflammatory disorder and/or an autoimmune disorder; wherein said polypeptide has at least 75% identity to SEQ ID NO 2, SEQ ID NO 4 or SEQ ID NO 6 or variants, homologues, fragments or derivatives thereof; and wherein said polynucleotide sequence encodes a polypeptide which has at least 75% identity to SEQ ID NO 2, SEQ ID NO 4 or SEQ ID NO 6 or variants, homologues, fragments or derivatives thereof and/or wherein said polynucleotide sequence has at least 75% identity to SEQ ID NO 1, SEQ ID NO 3 or SEQ ID NO 5 or variants, homologues, fragments or derivatives thereof.
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公开(公告)号：EP3369425A1
公开(公告)日：2018-09-05
申请号：EP18167277.5
申请日：2016-06-15
IPC分类号： A61K35/74 , A61P1/00 , A61P11/06 , A61P29/00 , A61P19/02 , A61P25/28 , A61P35/00 , A61P27/02
CPC分类号： A61K35/74 , A23L33/135 , A23L33/30 , A23V2002/00 , A61K9/19 , A61K2035/11 , C12R1/01
摘要： The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
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公开(公告)号：EP3240554A1
公开(公告)日：2017-11-08
申请号：EP16731640.5
申请日：2016-06-15
IPC分类号： A61K35/74 , C12N1/20 , A61P1/00 , A61P11/06 , A61P29/00 , A61P19/02 , A61P25/28 , A61P35/00 , A61K35/745
摘要： The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
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公开(公告)号：EP3065748A1
公开(公告)日：2016-09-14
申请号：EP15817513.3
申请日：2015-12-22
IPC分类号： A61K35/74
CPC分类号： A61K35/74 , A23L33/135 , A23V2002/00 , A61K9/0053 , A61K9/19 , C12N1/04 , C12R1/01
摘要： The present invention provides a strain of Bacteroides thetaiotaomicron and derivatives thereof, and the use of said strain or derivatives in treating inflammatory, autoimmune and allergic disorders. The invention also provides pharmaceutical compositions, nutritional supplements, feedstuffs, food products, dietary supplements, and food additives comprising said strain or derivatives.
摘要翻译： 本发明提供了拟杆菌拟杆菌菌株及其衍生物，以及所述菌株或衍生物在治疗炎症，自身免疫和变应性疾病中的用途。 本发明还提供了包含所述菌株或其衍生物的药物组合物，营养补充剂，饲料，食品，膳食补充剂和食品添加剂。
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69.发明授权
公开(公告)号：EP2763685B1
公开(公告)日：2016-04-20
申请号：EP12775538.7
申请日：2012-10-08
发明人： KELLY, Denise , MULDER, Imke
CPC分类号： A61K35/741 , A23K10/18 , A23L33/135 , A23V2002/00 , A61K9/0053 , A61K35/74 , A61K45/06 , A61K2035/115 , C12N1/20 , Y02A50/481
摘要： A first aspect of the invention relates to the bacterial species Roseburia hominis for use in: regulating the immine system of a subject; treating an immune disorder; treating an intestinal disorder; improving intestinal microbiota; regulating the innate immune system of a subject; regulating the adaptive immune system of a subject; regulating appetite in a subject; promoting Tregs and immune tolerance; promoting gut health in a subject; and/or maintaining immune homeostasis in a subject. Further aspects of the invention relate to compositions comprising Roseburia hominis.
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公开(公告)号：EP4096690A1
公开(公告)日：2022-12-07
申请号：EP21702261.5
申请日：2021-01-27
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