公开(公告)号：EP2673244A1

公开(公告)日：2013-12-18

申请号：EP12744637.5

申请日：2012-02-07

Applicant: BASF SE

Inventor： WEYRAUCH, Jan Philipp ,  WEIS, Martine ,  TELES, Joaquim Henrique ,  EBEL, Klaus ,  DEGLMANN, Peter

IPC: C07B41/14 ,  C07B41/02 ,  B01J23/18

CPC classification number: B01J23/18 ,  B01J23/002 ,  B01J27/25 ,  B01J2523/00 ,  C01B13/0214 ,  C07C39/08 ,  B01J2523/27 ,  B01J2523/54 ,  B01J2523/845

Abstract: The invention relates to a process for the oxidation of mesitol with singlet oxygen, which is re- leased from hydrogen peroxide, this release taking place in the presence of a bismuth com- pound as catalyst. In the process, 2,4,6-trimethylquinol is formed in high yield and selectivity as product, which can be used in further reactions for the synthesis of vitamins and in particular of vitamin A and vitamin E.

公开(公告)号：EP2625158A1

公开(公告)日：2013-08-14

申请号：EP11767683.3

申请日：2011-10-05

Applicant: BASF SE

Inventor： SCHELPER, Michael ,  STOCK, Christoph ,  EBEL, Klaus ,  TELES, Joaquim Henrique ,  PELZER, Ralf

IPC: C07C45/28 ,  C07C45/62 ,  C07C49/385 ,  C07C49/587

CPC classification number: C07C45/28 ,  C07C45/62 ,  C07C2601/18 ,  C07C49/587 ,  C07C49/385

Abstract: Ketones of the formula II where A is optionally alkyl-substituted C
2 -C
12 -alkanediyl, R
1 and R
2 are each, independently of one another, C
1 -C
6 -alkyl, or R
1 and R
2 together form optionally alkyl-substituted C
3 -C
10 -alkanediyl, and R
3 is hydrogen or C
1 -C
6 -alkyl, are prepared by reacting a cyclic olefin of the formula I with dinitrogen monoxide to form the ketone of the formula II. The ketone of the formula II can be further hydrogenated to form the saturated ketone of the formula III. Macrocyclic ketones of the formula III, e.g. muscone, are sought after as fragrances.

公开(公告)号：EP2234949B1

公开(公告)日：2013-02-20

申请号：EP08863003.3

申请日：2008-12-17

Applicant: BASF SE

Inventor： GRALLA, Gabriele ,  HEYDRICH, Gunnar ,  EBEL, Klaus ,  KRAUSE, Wolfgang

IPC: C07C37/07 ,  C07C37/20 ,  C07C37/62 ,  C07C39/15 ,  C07C39/367 ,  C07C45/74 ,  C07C49/613 ,  C07C49/653

CPC classification number: C07C45/74 ,  C07C37/07 ,  C07C37/20 ,  C07C37/62 ,  C07C49/613 ,  C07C49/653 ,  C07C39/15 ,  C07C39/367

公开(公告)号：EP2550248A2

公开(公告)日：2013-01-30

申请号：EP11711827.3

申请日：2011-03-24

Applicant: BASF SE

Inventor： EBEL, Klaus ,  RÜDENAUER, Stefan ,  PELZER, Ralf ,  BOCK, Martin

IPC: C07C29/44 ,  C07C31/135

CPC classification number: A61K8/34 ,  A61Q19/00 ,  C07C29/19 ,  C07C29/44 ,  C07C31/1355 ,  C07C2601/14 ,  Y02P20/544 ,  C07C33/20

Abstract: The present invention relates to a process for the preparation of 4-cyclohexyl-2-methyl-2-butanol. The process involves the following steps: a) reaction of styrene with isopropanol at elevated temperature, giving 4-phenyl-2-methyl-2-butanol, and b) heterogeneous-catalytic hydrogenation of 4-phenyl-2-methyl-2-butanol over a catalyst suitable for the ring hydrogenation of aromatics.

Abstract translation: 制备4-环己基-2-甲基-2-丁醇包括（a）在升高的温度下使苯乙烯与异丙醇反应，得到4-苯基-2-甲基-2-丁醇，和（b）进行非均相催化氢化 4-苯基-2-甲基-2-丁醇，适用于芳族化合物的环加氢。 还包括独立权利要求：（1）包含2-甲基-4-苯基-2-丁醇和2-甲基-4-苯基-2-戊醇的组合物; （2）制备2-甲基-4-苯基-2-丁醇和2-甲基-4-苯基-2-戊醇的组合物，其包括使苯乙烯与异丙醇在升高的温度下在超临界条件下存在异丙醇的条件下反应， 苯乙烯与异丙醇的摩尔比为1:10-1:130; （3）4-环己基-2-甲基-2-戊醇; （4）制备4-环己基-2-甲基-2-戊醇，其包括在适用于芳族化合物环加氢的催化剂上进行2-甲基-4-苯基-2-戊醇的非均相催化氢化; （5）包含4-环己基-2-甲基-2-戊醇的组合物; 和（6）包含额外的4-环己基-2-甲基-2-丁醇的组合物。

公开(公告)号：EP2432773A1

公开(公告)日：2012-03-28

申请号：EP10719340.1

申请日：2010-05-11

Applicant: BASF SE

Inventor： GRALLA, Gabriele ,  EBEL, Klaus ,  GRIESBACH, Ulrich ,  PELZER, Ralf ,  BOTZEM, Jörg

IPC: C07D309/12

CPC classification number: C07D309/12

Abstract: The present invention relates to a method for producing 2-substituted 4-hydroxy-4-methyl tetrahydropyranoles by reacting 3-methylbut-3-en-1-ol (isoprenol) with the corresponding aldehydes in the presence of a strongly acidic cation exchanger. The present invention particularly relates to a corresponding method for producing 2-isobutyl-4-hydroxy-4-methyl tetrahydropyrane by reacting isoprenol with isovaleraldehyde.

公开(公告)号：EP2321241A1

公开(公告)日：2011-05-18

申请号：EP09781102.0

申请日：2009-07-27

Applicant: BASF SE

Inventor： WEIS, Martine ,  BREUNINGER, Daniel ,  EBEL, Klaus ,  WINSEL, Harald

IPC: C07C29/149 ,  C07C67/317 ,  C07C67/343 ,  C07C69/65 ,  C07C69/738

CPC classification number: C07C67/317 ,  C07C29/149 ,  C07C67/343 ,  C07C69/65 ,  C07C69/738 ,  C07C33/46

Abstract: The present invention relates to a method for producing phenylalkane-1-ols 5 using three steps, wherein in the first step an ester condensation is carried out in the presence of alkali or alkaline earth alcoholates.

公开(公告)号：EP2200961A1

公开(公告)日：2010-06-30

申请号：EP08786349.4

申请日：2008-07-23

Applicant: BASF SE

Inventor： HEYDRICH, Gunnar ,  GRALLA, Gabriele ,  EBEL, Klaus ,  KRAUSE, Wolfgang ,  KASHANI-SHIRAZI, Nawid

IPC: C07C29/80 ,  C07C35/12 ,  B01J19/00 ,  B01D3/14

CPC classification number: B01D3/141 ,  B01D3/14 ,  C07B2200/07 ,  C07C29/80 ,  C07C2601/14 ,  C07C35/12 ,  C07C35/17

Abstract: The present invention relates to a continuous process for preparing racemic or optically active menthol in pure or enriched form by distillative removal of menthol from substance mixtures which comprise essentially menthol and diastereomers thereof. This distillative separation is carried out in a dividing wall column having from 50 to 300 theoretical plates and one or more side draw points at an absolute operating pressure of 5 to 500 mbar.

Abstract translation: 用于制备纯粹和富集形式的外消旋或光学活性薄荷醇的连续方法包括从含有外消旋或光学活性薄荷醇及其非对映体的材料混合物中蒸馏分离外消旋或光学活性薄荷醇，其中蒸馏分离过程在 分隔柱具有50-300理论分离步骤和一个或多个侧排气位置，绝对工作压力为5-500mbar。

公开(公告)号：EP1819654B1

公开(公告)日：2009-06-10

申请号：EP05810891.1

申请日：2005-11-24

Applicant: BASF SE

Inventor： BERGNER, Eike Johannes ,  EBEL, Klaus ,  JOHANN, Thorsten ,  LÖBER, Oliver

IPC: C07C29/17 ,  C07C35/12 ,  C07B53/00

CPC classification number: C07C29/17 ,  C07B2200/07 ,  C07C29/172 ,  C07C45/002 ,  C07C2601/14 ,  C12C11/02 ,  C07C33/025 ,  C07C35/12 ,  C07C29/56 ,  C07C35/17 ,  C07C47/21

Abstract: The invention relates to a method for producing optically active menthol from geraniol, nerol, or mixtures of geraniol and nerol by a) enantioselectively hydrogenating geraniol, nerol, or mixtures of geraniol and nerol to optically active citronellol, b) reacting the obtained optically active citronellol to optically active citronellal, c) cyclizing the obtained optically active citronellal to a mixture containing optically active isopulegol, and d) eliminating optically active isopulegol from the obtained mixture and hydrogenating the same to optically active menthol or hydrogenating the optically active isopulegol contained in the mixture to optically active menthol and eliminating the obtained optically active menthol from the mixture obtained as hydrogenation product.

Abstract translation: 方法包括：（a）使包含选自香叶醇，橙花醇及其混合物的组分的起始材料对称选择性氢化以形成光学活性香茅醇; （b）将光学活性香茅醇转化为光学活性香茅醛; （c）使光学活性香茅醛环化以形成包含光学活性的异胡前药的混合物; 和（d）对混合物进行进一步处理，其包括：（i）从混合物中分离光学活性异胡哥波，并氢化分离的光学活性异焦耳醇以形成光学活性薄荷醇; 或（ii）将混合物中的光学活性异胡胆碱氢化以形成光学活性薄荷醇并从混合物中分离光学活性薄荷醇。

公开(公告)号：EP1539666B1

公开(公告)日：2009-01-07

申请号：EP03748014.2

申请日：2003-09-12

Applicant: BASF SE

Inventor： VOLLAND, Martin ,  AHLERS, Wolfgang ,  EBEL, Klaus ,  PACIELLO, Rocco ,  RÖPER, Michael ,  MACKEWITZ, Thomas ,  BÖHM, Volker ,  SAVA, Xavier ,  LÖBER, Oliver ,  BEY, Oliver ,  STEPHAN, Jürgen ,  HAESE, Frank

IPC: C07C45/50 ,  C07C47/21 ,  C07C47/12 ,  C07F9/6558

CPC classification number: C07F9/6596 ,  C07C45/50 ,  C07F9/5721 ,  C07F9/5728 ,  C07F9/65522 ,  C07F9/65586 ,  C07F9/65842 ,  C07F9/65848 ,  C07C47/12 ,  C07C47/21

Abstract: The invention relates to a method for producing dialdehydes and/or ethylenically unsaturated monoaldehydes by reacting at least one compound with at least two ethylenically unsaturated double bonds with carbon monoxide and hydrogen in the presence of a hydroformylating catalyst with at least one complex of a metal of subgroup VIII. The subgroup comprises at least pnicogen chelate ligands.

公开(公告)号：EP1525176B1

公开(公告)日：2008-12-31

申请号：EP03764961.3

申请日：2003-07-10

Applicant: BASF SE

Inventor： WARTINI, Alexander ,  EBEL, Klaus ,  HIEBER, Gisela ,  WEIGL, Hagen

IPC: C07C45/48 ,  C07C49/385 ,  C07C49/587

CPC classification number: C07C45/48 ,  C07C49/587 ,  C07C49/385

Abstract: The invention relates to a method for producing macrocyclic ketones of general formula (I) by direct cyclisation of compounds of general formula (II) in the gas phase on a heterogeneous catalyst. In general formula (I), X represents a monounsaturated or polyunsaturated or saturated C10-C17 alkyl radical which can be optionally substituted by a C1-C6 alkyl radical, and in general formula (II), R1, R2 can respectively be the same or different and represent hydrogen or C1-C6 alkyl, and X has the above-mentioned designation.