-
公开(公告)号:EP4301725A1
公开(公告)日:2024-01-10
申请号:EP22844091.3
申请日:2022-12-22
发明人: MAESING, Florian , DIEKER, Jürgen
IPC分类号: C07C221/00 , C08G63/00 , C09D11/00
-
62.
公开(公告)号:EP4232434A1
公开(公告)日:2023-08-30
申请号:EP20855888.2
申请日:2020-10-26
申请人: Rossi Besio, Andrea
发明人: Rossi Besio, Andrea
IPC分类号: C07D221/20 , C07D221/18 , C07D237/26 , C07C47/00 , C07C221/00 , C09K11/06 , H05B33/14
-
公开(公告)号:EP3911660B1
公开(公告)日:2023-05-10
申请号:EP20741510.0
申请日:2020-01-14
发明人: VASIREDDI, Uma Maheswer Rao , KINTALI, Venkata Ramana , DADI, Jagadeeswara Rao , KATKURI, Raj Koti , TUMMU, Sridhar
IPC分类号: C07C68/02 , C07C69/96 , C07C201/08 , C07C201/12 , C07C205/45 , C07C221/00 , C07C225/22
-
64.
公开(公告)号:EP4116288A1
公开(公告)日:2023-01-11
申请号:EP21184477.4
申请日:2021-07-08
发明人: Bezensek, Jure , Andolsek, Barbara
IPC分类号: C07C213/00 , C07C213/08 , C07C221/00 , C07C225/16 , C07C217/72 , C07C217/62
摘要: The present invention provides means and methods for synthesizing tapentadol with increased yield. The processes of the present invention involve a step of racemization of (R)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one.
-
公开(公告)号:EP3118204B1
公开(公告)日:2022-04-20
申请号:EP15740755.2
申请日:2015-01-14
发明人: BU, Xianzhang , ZHU, Cuige , YUE, Xin , ZUO, Yinglin , CHEN, Yu , WEN, Gesi
IPC分类号: C07C225/22 , A61P35/00 , C07D295/112 , C07C253/30 , C07F9/12 , C07C49/835 , C07C49/84 , C07C45/45 , C07C221/00
-
公开(公告)号:EP3956292A1
公开(公告)日:2022-02-23
申请号:EP20717602.5
申请日:2020-04-02
申请人: EDMOND PHARMA S.R.L.
IPC分类号: C07C213/08 , C07C221/00 , C07C215/34 , C07C225/16
-
公开(公告)号:EP3746532B1
公开(公告)日:2022-02-23
申请号:EP19730386.0
申请日:2019-06-18
IPC分类号: C11B9/00 , A23L27/20 , A23L27/29 , A23L27/00 , C07C317/24 , C07C323/22 , C07C221/00 , C07C59/185 , C07C49/175
-
公开(公告)号:EP3725765A1
公开(公告)日:2020-10-21
申请号:EP19170053.3
申请日:2019-04-18
申请人: EDMOND PHARMA S.R.L.
IPC分类号: C07C213/08 , C07C221/00 , C07C225/16 , C07C215/34
摘要: The invention concerns a new, efficient process for the preparation of enantiomerically pure norepinephrine (also known as noradrenaline), or an addition salt thereof, using a catalytic hydrogenation system under hydrogen donor transfer. The invention also discloses a novel intermediate and the process for the preparation thereof.
-
公开(公告)号:EP3713911A1
公开(公告)日:2020-09-30
申请号:EP18769245.4
申请日:2018-08-14
发明人: BERKES, Dusan , MARKUS, Jozef
IPC分类号: C07C213/00 , C07C213/08 , C07C215/54 , C07C217/62 , C07C217/72 , C07C219/28 , C07C221/00 , C07C225/16 , C07B53/00
-
公开(公告)号:EP3590919A1
公开(公告)日:2020-01-08
申请号:EP18761809.5
申请日:2018-03-02
IPC分类号: C07C225/10 , C07C209/28 , C07C211/56 , C07C221/00 , C07C253/30 , C07C255/58 , C07D265/38 , C07D285/14 , C07F5/02 , C09K3/00 , C09K11/06 , C07B61/00
摘要: Provided are a donor-acceptor type compound having a novel structure and its use.
An enamine compound represented by general formula (1)
(in the formula:
R 1 represents an electron-withdrawing group;
A represents a divalent aromatic hydrocarbon group which may contain a substituent, a divalent aromatic heterocyclic group which may contain a substituent or a divalent unsaturated aliphatic hydrocarbon group which may contain a substituent;
R 2 represents a hydrogen atom or a hydrocarbon group which may contain a substituent;
R 3 and R 4 are the same or different from each other and represent an aromatic hydrocarbon group which may contain a substituent or an aromatic heterocyclic group which may contain a substituent, or R 3 and R 4 together form an optionally substituted bicyclic aromatic heterocyclic group containing two or more nitrogen atoms or a nitrogen atom and an oxygen atom or a sulfur atom, or a tricyclic aromatic heterocyclic group which may contain a substituent; and
R 2 and A, or R 2 and R 3 may together form a cyclic structure).
-
-
-
-
-
-
-
-
-