摘要:
The present invention provides an adjuvant containing a hydroxy unsaturated fatty acid, as well as a vaccine containing the adjuvant as a constituent. For example, a vaccine capable of sufficiently enhancing the immunity is provided by administering a hydroxy unsaturated fatty acid having the following structure:
摘要:
Described herein are adjuvants containing as the active ingredient an attenuated toxin having a residual activity of at least 1/2000 the activity of the natural toxin and vaccines containing such adjuvants. By using, for example, attenuated natural cholera toxin, vaccines capable of showing sufficient immune potentiation in percutaneous vaccination or nasal vaccination can be presented.
摘要:
The present invention provides improved methods and compositions for producing oocysts. The oocysts produced according to the invention find use in the manufacture of vaccines. In preferred embodiments, the present invention provides methods and compositions for the production of Eimeria oocysts. Vaccines containing Eimeria oocysts, sporocysts and/or sporozoites produced according to the present invention may be used to immunize birds against coccidiosis either in ovo or post hatch.
摘要:
The present invention is drawn to an isolated recombinant polynucleic acid comprising a nucleotide sequence, SEQ.ID.NO: 4 encoding 250kD protein comprising the amino acid sequence as represented by SEQ.ID.N: 6 from Eimeria maxima sporozoites/merozoites. This invention is further drawn to avian coccidiosis vaccine compositions against E.tenella, E.maxima, E.acervulina, E.necatrix, E.mitis, and E.brunetti etc.
摘要:
Methods are provided for the sporulation, sterilization and storage of coccidial oocyst which are characterized by an absence of the highly toxic chemical potassium dichromate. Also provided are compositions containing sporulated oocysts which are free of potassium dichromate.
摘要:
Disclosed herein is a process for preparing pre-harvest tissue culture produced T. gondii that is suitable for a commercial scale vaccine for protection of cats against T. gondii ; the vaccine contains an effective amount of bradyzoites and is free of or substantially free of tachyzoites.