公开(公告)号：EP1206287A1

公开(公告)日：2002-05-22

申请号：EP00936075.1

申请日：2000-05-19

申请人： MICRO THERAPEUTICS, INC.

发明人： WHALEN, Thomas, J. ,  TRAN, Chinh, N. ,  ROTH, Noah, M. ,  GREFF, Richard, J.

IPC分类号： A61K49/04

CPC分类号： A61L24/08 ,  A61K49/0002 ,  A61K49/0409 ,  A61L24/001 ,  A61L24/02 ,  A61L24/046 ,  A61L24/06 ,  A61L27/56 ,  A61L27/58 ,  A61L2430/36

摘要： Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery.

公开(公告)号：EP1180050A1

公开(公告)日：2002-02-20

申请号：EP00932602.6

申请日：2000-05-19

申请人： MICRO THERAPEUTICS, INC.

发明人： HAYMAN, Douglas, R. ,  OLSEN, Ed ,  ROTH, Noah, M. ,  CURRI, Gary ,  WHALEN, Tom

IPC分类号： A61M25/16

CPC分类号： A61M25/0097 ,  A61M5/1407 ,  A61M2005/3201

摘要： An interface needle (12) is used for connecting a syringe (14) to a catheter (10) to create a blunt interface between two or more liquids being delivered through the catheter (10). The interface needle (12) is particularly useful for creating a blunt interface between a bio-compatible solvent and a liquid embolic composition which is delivered to the body for treatment of various conditions including aneurysms. A system for liquid delivery with a blunt liquid interface includes a catheter (10) or other cannula, an interface needle (12), and a syringe (14). The interface needle (12) includes a tube (36) extending from a distal end which delivers liquid to a lumen of the catheter (10) bypassing a reservoir (36) in the catheter hub (28) to create the blunt liquid interface. One embodiment of the interface needle (12) controls an injection pressure of high viscosity liquids.

公开(公告)号：EP1163012A1

公开(公告)日：2001-12-19

申请号：EP00918170.2

申请日：2000-03-20

申请人： MICRO THERAPEUTICS, INC.

发明人： RICCI, Charlie ,  DOLMATCH, Bart ,  CRAGG, Andrew, H. ,  GREFF, Richard, J.

IPC分类号： A61K51/00 ,  A61M36/14

CPC分类号： A61B17/12186 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12118 ,  A61K47/6957

摘要： Disclosed are methods for inhibiting endoleak formation associated with endovascular repair of abdominal aortic aneurysms.

公开(公告)号：EP0843560B1

公开(公告)日：2001-12-12

申请号：EP96926155.1

申请日：1996-07-29

申请人： MICRO THERAPEUTICS, INC.

发明人： GREFF, Richard, J. ,  JONES, Michael, L. ,  EVANS, Scott

IPC分类号： A61K49/04 ,  A61L24/02 ,  A61L24/04 ,  A61L31/02 ,  A61L31/04

CPC分类号： A61L24/06 ,  A61K49/0414 ,  A61L24/001 ,  A61L24/046 ,  A61L24/08 ,  A61L2430/36 ,  C08L1/26

摘要： Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise a cellulose diacetate polymer, a biocompatible solvent and a water insoluble contrasting agent selected from the group consisting of tantalum, tantalum oxide and barium sulfate. Also disclosed are methods for embolizing a blood vessel using the compositions described herein.

公开(公告)号：EP1148909A1

公开(公告)日：2001-10-31

申请号：EP00911693.0

申请日：2000-02-01

申请人： MICRO THERAPEUTICS, INC.

发明人： GULACHENSKI, Joseph A.

IPC分类号： A61M25/00 ,  A61M25/10

CPC分类号： A61M25/0075 ,  A61M25/10

摘要： A balloon catheter having a proximal end and a distal end and a main axial lumen extending therebetween is provided with an inflation seal such that the presence of a guidewire in the inflation seal forms a fluid-tight seal for retaining fluid in the balloon and causing inflation thereof. The inflation seal can be formed distally of the balloon or within the balloon. Marker bands disposed at the distal end are formed integrally with the structure of the balloon catheter.

公开(公告)号：EP1091724A1

公开(公告)日：2001-04-18

申请号：EP99933648.0

申请日：1999-07-02

申请人： MICRO THERAPEUTICS, INC.

发明人： GREFF, Richard, J.

IPC分类号： A61J1/00

CPC分类号： A61L24/04 ,  A61K49/0404 ,  A61K49/0419 ,  A61L24/001 ,  A61L24/08 ,  A61L2430/36 ,  C08L1/12

摘要： Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery. In one embodiment, the compositions of this invention comprise a biocompatible polymer, ethyl lactate solvent and a biocompatible contrast agent.

公开(公告)号：EP1011781A4

公开(公告)日：2001-02-07

申请号：EP98910226

申请日：1998-03-06

申请人： MICRO THERAPEUTICS INC

发明人： KONYA ANDRAS ,  WALLACE SIDNEY ,  WRIGHT KENNETH C

IPC分类号： A61F2/84 ,  A61F2/06 ,  A61F2/82 ,  A61F2/88 ,  A61M29/00

CPC分类号： A61F2/88 ,  A61F2/95 ,  A61F2002/9511

摘要： This invention is a stent (1) comprising a single wire (2) fashioned into hoops (5) connected with radially offset struts (7).

公开(公告)号：EP1028758A1

公开(公告)日：2000-08-23

申请号：EP98957553.5

申请日：1998-11-03

申请人： MICRO THERAPEUTICS, INC.

发明人： GREFF, Richard, J. ,  WALLACE, George

IPC分类号： A61K51/12 ,  A61K49/04 ,  A61N5/00

CPC分类号： A61K51/06 ,  A61K51/1217 ,  A61K2121/00

摘要： Disclosed are methods for treating solid mass prostate tumors in a male mammal by use of a radiation composition.

公开(公告)号：EP1011520A4

公开(公告)日：2000-07-19

申请号：EP97943354

申请日：1997-09-18

申请人： MICRO THERAPEUTICS INC

发明人： WALLACE GEORGE ,  LENKER JAY ,  GREENE ROBERT R JR ,  BRENNEMAN RODNEY A

IPC分类号： A61B17/12 ,  A61B17/122 ,  A61F2/00 ,  A61F2/82 ,  A61F2/90 ,  A61F2/92 ,  A61F2/95 ,  A61F2/962 ,  A61F2/04 ,  A61F2/06 ,  A61M29/00

CPC分类号： A61F2/962 ,  A61B17/12022 ,  A61B17/12118 ,  A61B17/122 ,  A61B2017/1205 ,  A61B2017/12063 ,  A61B2017/12068 ,  A61F2/90 ,  A61F2/92 ,  A61F2002/823 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0095 ,  A61F2250/0071 ,  A61F2250/0098

摘要： This invention is a stent (1) and stent catheter (2) for intracranial use. The stent is a rolled sheet stent (20) and is releasably mounted on the distal tip (21) of the catheter by means of a low profile or non-sliding retention and release mechanism. The low profile or non-sliding release mechanism (22) is operated remotely at the proximal end of the catheter by means of a linear translator (23). The stent is rolled tightly on the distal tip of the catheter and flexibility of the tightly rolled stent is promoted by ribbed or slatted construction (or, alternatively, slotted construction) in which the various layers of the stent are provided with numerous slats which counter align when the stent is expanded to form an imperforate wall from a plurality of perforate layers.

摘要翻译： 本发明是一种用于颅内使用的支架（1）和支架导管（2）。 该支架是卷片支架（20）并且借助于低轮廓或非滑动保持和释放机构可释放地安装在导管的远端尖端（21）上。 低轮廓或非滑动释放机构（22）通过线性转换器（23）在导管的近端远程操作。 支架在导管的远侧尖端上紧密卷绕，并且紧密卷绕的支架的柔性通过肋或板条构造（或者可选地，开槽构造）促进，其中支架的各层设置有多个反向对齐的板条 当支架膨胀以从多个穿孔层形成无孔壁时。

公开(公告)号：EP0936890A1

公开(公告)日：1999-08-25

申请号：EP97911674.0

申请日：1997-10-10

申请人： Micro Therapeutics, Inc.

发明人： WALLACE, George ,  GREFF, Richard, J.

IPC分类号： A61F2 ,  A61L24 ,  A61L27 ,  A61L31

CPC分类号： A61L31/042 ,  A61F2/0036 ,  A61L24/06 ,  A61L24/08 ,  A61L27/16 ,  A61L27/20 ,  A61L31/048 ,  A61L2430/36 ,  A61L27/50 ,  A61F2/00 ,  C08L1/12 ,  C08L33/20 ,  C08L33/08 ,  C08L29/04 ,  C08L33/00

摘要： Disclosed are methods for treating urinary incontinence in a mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the periurethral tissue of the mammal.