利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

1032 条记录 (耗时 0.027 秒)

    Antithrombotic coating for drug eluting medical devices
    72.
    发明公开
    Antithrombotic coating for drug eluting medical devices 有权
    Antithrombotische Beschichtungfürdie mit den Medikamenten beschichteten medizinischen Vorrichtungen

    公开(公告)号：EP1759724A1

    公开(公告)日：2007-03-07

    申请号：EP06254407.7

    申请日：2006-08-23

    申请人： Cordis Corporation

    发明人： Falotico, Robert ,  Zhao, Jonathon Z.

    IPC分类号： A61L31/16 ,  A61L31/04 ,  A61L33/00 ,  A61L33/06

    CPC分类号： A61L33/0029 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/61

    摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.
    In one embodiment an intraluminal medical device comprises a scaffold structure having a luminal surface and an abluminal surface; a first layer affixed to the luminal and abluminal surfaces, the first layer including at least one first therapeutic agent; and a second layer affixed to the first layer, the second layer including at least one second therapeutic agent in combination with a water soluble polymeric material and a water insoluble polymeric material.

    摘要翻译： 可以涂覆医疗装置，特别是可植入医疗装置，以最小化或基本上消除生物体对将生物体引入医疗装置的反应。 医疗装置可以涂覆任何数量的生物相容性材料。 治疗药物，药剂或化合物可以与生物相容性材料混合并固定在医疗装置的至少一部分上。 这些治疗药物，药剂或化合物还可以进一步降低生物体对将生物体引入医疗装置的反应。 此外，这些治疗药物，药剂和/或化合物可用于促进愈合，包括血块的形成。 可以使用各种材料和涂覆方法来将药物，试剂或化合物维持在医疗装置上，直到被输送和定位。 在一个实施例中，管腔内医疗装置包括具有管腔表面和腔内表面的支架结构; 第一层，其固定到所述管腔和囊腔表面，所述第一层包括至少一种第一治疗剂; 以及固定到第一层的第二层，第二层包括与水溶性聚合物材料和水不溶性聚合物材料组合的至少一种第二治疗剂。

    Intravascular, interstitial or intraorgan medical device comprising a nitric oxide eluting polymer
    75.
    发明公开
    Intravascular, interstitial or intraorgan medical device comprising a nitric oxide eluting polymer 审中-公开
    Medizinische Vorrichtungfürintravasculäre，interstitiel oder intra-Organ-Applikation mit einem Stickstoffoxide abgebendenPolymerüberzug

    公开(公告)号：EP1704879A1

    公开(公告)日：2006-09-27

    申请号：EP05006489.8

    申请日：2005-03-24

    申请人： NOLabs AB

    发明人： Peters, Tor

    IPC分类号： A61L29/16 ,  A61L29/14 ,  A61L33/00

    CPC分类号： A61L29/16 ,  A61L29/148 ,  A61L33/0005 ,  A61L2300/114

    摘要： A intravascular, interstitial or intraorgan medical device, and a manufacturing process of said medical device, is provided that allows for prevention of infection and obtainment of anti-thrombotic effect. The medical device comprises a nitric oxide (NO) eluting polymer arranged adjacent mammal tissue, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said mammal tissue.

    摘要翻译： 提供血管内，间质或有机体内的医疗装置以及所述医疗装置的制造方法，其允许预防感染和获得抗血栓形成作用。 医疗装置包括邻近哺乳动物组织布置的一氧化氮（NO）洗脱聚合物，使得治疗剂量的一氧化氮从所述一氧化氮洗脱聚合物洗脱到所述哺乳动物组织。