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公开(公告)号：EP3889263A1
公开(公告)日：2021-10-06
申请号：EP18944354.2
申请日：2018-12-24
申请人： Huang, Haidong , Zhou, Xiaoyi , Chen, Hanqiang
发明人： HUANG, Haidong
IPC分类号： C12N15/12 , C07K14/705 , A61K38/17 , A61P35/00
摘要： The present disclosure relates to the field of genetic engineering, in particular to a mutant human 2Ig-B7-H3 protein encoding gene, a protein, a recombinant vector, and a pharmaceutical composition including the gene or protein. The regulatory expression, interaction and signal transmission of the protein encoded by the gene of the present disclosure play an extremely important role in the tumor immune response process, and especially provide a new and beneficial way for the prevention and treatment of cancer.
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公开(公告)号：EP3886887A1
公开(公告)日：2021-10-06
申请号：EP19891408.7
申请日：2019-11-27
发明人： HENRICH, Ian , CHOU, Margaret M.
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84.发明公开
公开(公告)号：EP3878946A1
公开(公告)日：2021-09-15
申请号：EP19881986.4
申请日：2019-10-15
申请人： NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY , KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
发明人： FUKUDA, Junji , KAGEYAMA, Tatsuto , TATE, Yoshiki
IPC分类号： C12N5/071 , C12N5/077 , C12N5/0775 , C12N15/12 , C12Q1/6809
摘要： Provided are a hair follicle germ having excellent hair growth-related properties, a method of producing a hair follicle germ, and a method of activating cells contained in a hair follicle germ. The hair follicle germ includes: epithelial cells; mesenchymal cells; and mesenchymal stem cells. The method of producing a hair follicle germ includes co-culturing epithelial cells, mesenchymal cells, and mesenchymal stem cells to form a hair follicle germ.
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85.发明公开
公开(公告)号：EP3873536A1
公开(公告)日：2021-09-08
申请号：EP19877633.8
申请日：2019-11-01
申请人： Momotaro-Gene Inc.
发明人： KUMON, Hiromi , BURT, Bryan
IPC分类号： A61K48/00 , A61P35/00 , A61K35/761 , C12N15/12 , C12N15/861
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公开(公告)号：EP3865146A1
公开(公告)日：2021-08-18
申请号：EP19868580.2
申请日：2019-10-04
发明人： SUGIYAMA Haruo
IPC分类号： A61K38/04 , A61K39/39 , A61K48/00 , A61P35/00 , C07K14/82 , C12N5/0783 , C12N5/10 , C12N15/12
摘要： The present disclosure provides a composition for preventing or treating a benign tumor. Provided is a composition for preventing or treating a benign tumor that comprises a WT1 peptide or an analog thereof, or a nucleic acid molecule encoding a WT1 peptide or an analog thereof. In a specific embodiment, the present disclosure provides a composition for preventing or treating a benign tumor that comprises a WT1 peptide or an analog thereof, or a nucleic acid molecule encoding a WT1 peptide or an analog thereof. In a preferred embodiment, the composition for preventing or treating a benign tumor (e.g. familial adenomatous polyposis) according to the present disclosure comprises a killer type WT1 peptide and/or a helper type WT1 peptide. In a further preferred embodiment, the WT1 peptide is WT1 126 killer peptide and/or WT1 35 helper peptide. In another aspect, provided are a method of inducing WT1 peptide-specific CTLs, a method of inducing WT1-specific helper T cells, and a method of inducing dendritic cells presenting a WT1 peptide.
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公开(公告)号：EP3865141A1
公开(公告)日：2021-08-18
申请号：EP19871275.4
申请日：2019-10-07
IPC分类号： A61K35/76 , A61K31/739 , A61K35/741 , A61K38/19 , A61K39/395 , A61K45/00 , A61K48/00 , A61P35/00 , A61P43/00 , C07K14/115 , C07K14/715 , C12N7/04 , C12N15/12
摘要： An anticancer agent contains a virus presenting a desired protein or peptide on a virus particle envelope, as an active ingredient.
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公开(公告)号：EP3861111A1
公开(公告)日：2021-08-11
申请号：EP19869453.1
申请日：2019-10-03
申请人： Novozymes A/S
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