摘要:
A method of assessing the in vivo state of phagocytes in a patient, possibly indicating diagnostically important states such as inflammation or infection, which method utilizes chemiluminescent (CL) light emitted during the reaction in vitro between a CL substrate and the reactive oxygen species (ROS) formed in a fluid sample obtained from the patient. The measurement is performed in two or more portions of the sample, with stimulated phagocytes affected by one or more priming agents which shift the functional state of the phagocytes, providing a plurality of measurements, which are analyzed so as to distinguish intracellular and extracellular contributions to the CL kinetics. The results are compared with a range of control measurements performed with patients suffering from various diagnostic conditions.
摘要:
A process for producing a fuel composition from vegetable and/or animal oil comprises hydrodeoxygenating and hydroisomerizing the oil in a single step. The fuel composition has acceptable lubricity and comprises a mixture of C14 to C18 paraffins having a ratio of iso to normal paraffins of 2 to 8 and less than 5 ppm sulfur.
摘要:
The present invention relates generally to the mitochondrial protein, voltage- dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDACl and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.
摘要:
The invention relates to stable preparations of saponin nanovesicles, which can encapsulate active biological or chemical materials such as drugs, pesticides, vitamins, minerals and nutrients, and protect them. The preparations can be used, for example, in agricultural, pesticidal, dermatological and cosmetic compositions. The saponins per se can further be used as adjuvants for irrigation water. The invention further relates to novel saponins extracted from Balanites aegyptiaca.
摘要:
A method for operating a tapered flow pressure driven arrangement containing a plurality of membrane modules, which comprises positioning said membrane modules in at least two successively arranged flow stages, such that the number of membrane modules operating in parallel in a given flow stage is greater than their number in the consecutive flow stage, passing a feed stream through a flow stage to generate a permeate and a concentrate, directing said concentrate to the consecutive flow stage and passing said concentrate therethrough, while periodically replacing one or more of the membrane modules belonging to said consecutive flow stage with one or more membrane modules belonging to the previous flow stage, wherein the periodicity of said replacement is such that the surface of membranes disposed in said consecutive flow stage is exposed to super-saturation conditions associated with the passage of said concentrate for a period of time that is shorter than the time required for said concentrate to precipitate therefrom one or more sparingly soluble salts and/or minerals, onto the surface of the membranes in said consecutive flow stage under said super-saturation conditions, or before deposit of organic substances can occur in the first of said two or more successively arranged flow stages. An apparatus for carrying out the aforementioned method is also provided.
摘要:
The present invention provides a photoreactive reagent that binds specifically to Ca2+-binding proteins, links to them covalently after photo-activation, and labels them. The novel reagent enables the characterization, purification, inhibition and screening of Ca2+-binding proteins, as well as the preparation of a new affinity chromatography matrix and a new protein biosensor. The invention also relates to the use of the reagent in inhibiting apoptosis and necrosis and in diagnosing a disorder associated with a defect in the function of a Ca2+-binding protein, and in the preparation of a medicament for treating such disorders.
摘要:
The present invention relates generally to the mitochondrial protein, voltage- dependent anion channel (VDAC)5 polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.
摘要:
There is provided a composite membrane, which may include an electronically conductive asymmetric porous support and an electro-polymerized selective layer. There is also provided a composite membrane for water application(s), which may include an electronically conductive porous support and an electro-polymerized selective layer. Moreover, there is provided a composite membrane for gas application(s), which may include an electronically conductive asymmetric porous support and an electro-polymerized selective layer. There is also provided a membrane system which may include at least one composite membrane which may include an electronically conductive asymmetric porous support and an electro-polymerized selective layer. In addition there is provided a method for the preparation of a composite membrane.