公开(公告)号：EP2516677A4

公开(公告)日：2013-10-02

申请号：EP10838414

申请日：2010-12-22

申请人： GENETIC TECHNOLOGIES LTD

发明人： MANTZARIS DEBBIE ,  ALLMAN RICHARD ,  CANTSILIERIS STUART ,  VOM EDUARDO ,  ASHDOWN MARIA LUISA

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6806 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/156 ,  C12Q2523/32

公开(公告)号：EP2395922A4

公开(公告)日：2013-07-10

申请号：EP10735423

申请日：2010-01-25

申请人： GENETIC TECHNOLOGIES LTD

发明人： VOM EDUARDO ,  LEWIS CRAIG MATTHEW ,  ALLMAN RICHARD ,  MANTZARIS DEBBIE

IPC分类号： A61B10/00 ,  A61B10/02

CPC分类号： A61B10/0291 ,  A61B10/0096 ,  A61B10/0283 ,  A61B90/06 ,  A61B2010/0074 ,  A61B2010/0216 ,  A61B2090/036 ,  A61B2090/062 ,  A61B2090/0807 ,  A61F13/38

公开(公告)号：EP1886138A4

公开(公告)日：2009-04-15

申请号：EP06721493

申请日：2006-05-11

申请人： GENETIC TECHNOLOGIES LTD

发明人： BOEHMER RALPH MICHAEL ,  ALLMAN RICHARD

IPC分类号： G01N33/53 ,  C12Q1/68 ,  G01N33/569 ,  G01N33/68

CPC分类号： C12Q1/6881 ,  C12Q1/6879 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N33/5002 ,  G01N33/5044 ,  G01N33/5091 ,  G01N33/5094 ,  G01N33/54326 ,  G01N33/56966 ,  G01N33/573

摘要： The present invention relates to methods of enriching fetal cells from a pregnant female. The present invention relates to removing, from a sample, cells that comprise at least one MHC molecule. The present invention also relates to methods that rely on using telomerase, mRNA encoding components thereof, as well as telomere length, as markers for fetal cells. Enriched fetal cells can be used in a variety of procedures including, detection of a trait of interest such as a disease trait, or a genetic predisposition thereto, gender typing and parentage testing.

公开(公告)号：EP2250497A4

公开(公告)日：2011-08-24

申请号：EP09712569

申请日：2009-02-18

申请人： GENETIC TECHNOLOGIES LTD

发明人： MANTZARIS DEBBIE ,  ALLMAN RICHARD

IPC分类号： G01N33/483 ,  C12N5/073 ,  C12Q1/68 ,  C12N5/08 ,  C12N5/06

CPC分类号： C12N5/0603

公开(公告)号：EP1546403A4

公开(公告)日：2006-12-13

申请号：EP03794708

申请日：2003-09-15

申请人： GENETIC TECHNOLOGIES LTD

发明人： NORTH KATHRYN NANCE

IPC分类号： A63B69/00 ,  C12N15/09 ,  C12N15/12 ,  C12Q1/68 ,  G01N33/53 ,  G06Q50/22

CPC分类号： C12Q1/6888 ,  C12Q1/6876 ,  C12Q2600/156 ,  G06Q50/22 ,  Y02A90/22

摘要： The present invention concerns novel methods of selecting or matching a sport or sporting event to an individual (e.g. a sprint/power sport or an endurance sport) and predicting athletic performance, the methods involving assessing ACTN3 genotype. In alternative embodiments, training regimens may be optimally designed for athletes by assessing the ACTN3 genotypes. Certain embodiments concern combining the assessment of the ACTN3 genotype with other known fitness-related genes to better assess the athletic potential of an individual. In addition, the genotypic analysis of the ACTN3 gene may be combined with physiological tests, physical measurements and/or psychological assessments to more optimally design a training regimen for an individual athlete.

公开(公告)号：EP2488644A4

公开(公告)日：2013-03-27

申请号：EP10822895

申请日：2010-10-13

申请人： GENETIC TECHNOLOGIES LTD

发明人： ALLMAN RICHARD ,  VOM EDUARDO ,  LEWIS CRAIG MATTHEW ,  MANTZARIS DEBBIE ,  CANTSILIERIS STUART

IPC分类号： C12N15/10 ,  C12N15/11 ,  C12Q1/68

CPC分类号： C12N15/1003 ,  C12Q1/6806 ,  C12Q2525/204 ,  C12Q2521/331

公开(公告)号：EP2438193A4

公开(公告)日：2012-11-21

申请号：EP10782820

申请日：2010-06-01

申请人： GENETIC TECHNOLOGIES LTD

发明人： HINDS DAVID A ,  WALSER BRYAN

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/156 ,  C12Q2600/172

摘要： The present invention relates to methods and systems for assessing the overall risk of a human female subject for developing a breast cancer phenotype. In particular, the present invention relates to combining clinical risk assessment and genetic risk assessment to improve risk analysis.

公开(公告)号：EP2421955A4

公开(公告)日：2012-10-10

申请号：EP10766487

申请日：2010-04-20

申请人： GENETIC TECHNOLOGIES LTD

发明人： ALLMAN RICHARD ,  MANTZARIS DEBBIE ,  VOM EDUARDO ,  LEWIS CRAIG MATTHEW

IPC分类号： C12N5/073 ,  C12N15/10 ,  C12Q1/68 ,  G01N33/50 ,  G01N33/68

CPC分类号： C12Q1/6879 ,  C12N15/1003 ,  C12Q1/6806 ,  C12Q2600/156 ,  G01N33/483 ,  G01N33/5076 ,  G01N2015/1006

公开(公告)号：EP1532453A4

公开(公告)日：2008-03-05

申请号：EP03722092

申请日：2003-05-30

申请人： GENETIC TECHNOLOGIES LTD

发明人： BOHMER RALPH

IPC分类号： G01N33/53 ,  C12N5/00 ,  C12N5/06 ,  C12Q1/04 ,  G01N21/78 ,  G01N33/543 ,  G01N33/567 ,  G01N33/569 ,  G01N33/68 ,  G01N33/80

CPC分类号： G01N33/56966 ,  G01N33/56977 ,  G01N33/6854 ,  G01N33/689 ,  G01N2800/36 ,  G01N2800/368 ,  Y10T436/101666 ,  Y10T436/25125 ,  Y10T436/25375

摘要： The present invention provides methods for identifying and/or enriching fetal cells from maternal blood, using as fetal cell markers the antibodies that the mother produces against paternally inherited fetal antigens. The fetal cell-maternal antibody complexes are identified and isolated using labelled agents that bind to the maternal antibodies. The present invention also provides fetal cells, isolated by use of said maternal antibodies, as a source of fetal DNA for prenatal genetic diagnosis of the fetus.

公开(公告)号：EP1599608A4

公开(公告)日：2007-07-18

申请号：EP04717522

申请日：2004-03-05

申请人： GENETIC TECHNOLOGIES LTD

发明人： BOHMER RALPH MICHAEL

IPC分类号： C12Q1/68 ,  G01N33/50 ,  G01N33/569

CPC分类号： C12Q1/68 ,  C12Q1/6858 ,  C12Q1/6881 ,  C12Q2600/156 ,  C12Q2600/16 ,  G01N33/5044 ,  G01N33/5091 ,  G01N33/5094 ,  G01N33/56977

摘要： The present invention relates to the identification of fetal specific nucleic acids and fetal cell markers in maternal plasma or serum. In particular, the present invention relates to methods which rely on the analysis of polymorphic alleles of a population to determine an allele which is possessed by the fetus but absent from the mother. Fetal specific alleles identified using the methods of the invention can be used to quantify fetal DNA from maternal plasma or serum. In addition, antigens encoded by alleles identified using the methods of the invention can be targeted in methods of isolating or detecting fetal cells.