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1.
公开(公告)号:EP3434690A2
公开(公告)日:2019-01-30
申请号:EP17770648.8
申请日:2017-03-23
发明人: CHUNG, Junho , KIM, Ki-Hyun , KIM, Hyori , OH, Myoung-don , PARK, Wan Beom , KIM, Seungtaek , KIM, Jinhee
IPC分类号: C07K16/10 , C07K14/005 , G01N33/543 , G01N33/569 , G01N35/00
摘要: The present invention relates to an antibody which specifically binds to the envelope glycoprotein of severe fever with thrombocytopenia syndrome virus (SFTSV), the pathogen of severe fever with thrombocytopenia syndrome (SFTS), and is used in order to effectively detect or diagnosis SFTSV and treat SFTS.
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2.COMPOUNDS FOR TREATING VIRAL INFECTIONS 审中-公开
标题翻译: VERBINDUNGEN ZUR BEHANDLUNG VON VIRUSINFEKTIONEN公开(公告)号:EP3131890A1
公开(公告)日:2017-02-22
申请号:EP15715776.9
申请日:2015-04-17
发明人: WINDISCH, Marc P. , KIM, Hee-Young , YANG, Jaewon , HWANG, Jong Yeon , JO, Suyeon , KWON, Jeongjin , PARK, Dongsik , CHOI, Jihyun , LEE, Jaeheon
IPC分类号: C07D333/68 , C07D401/04 , C07D401/06 , C07D401/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D487/04 , C07D495/04 , C07D211/14 , C07D211/44 , C07D295/12 , C07D211/58 , A61K31/381 , A61K31/435
CPC分类号: C07D495/04 , A61K31/4365 , A61K45/06 , C07D211/14 , C07D211/44 , C07D211/58 , C07D295/12 , C07D333/68 , C07D401/04 , C07D401/06 , C07D401/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D487/04
摘要: The present invention relates to small molecule compounds and their use in the treatment of diseases, in particular viral diseases, in particular hepatitis C virus (HCV).
摘要翻译: 本发明涉及小分子化合物及其用于治疗疾病,特别是病毒性疾病,特别是丙型肝炎病毒(HCV)的用途。
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公开(公告)号:EP2523956A1
公开(公告)日:2012-11-21
申请号:EP11700392.1
申请日:2011-01-13
发明人: NO, Zaesung , KIM, Jaeseung , BRODIN, Priscille , SEO, Min Jung , PARK, Eunjung , CECHETTO, Jonathan , JEON, Heekyoung , GENOVESIO, Auguste , LEE, Saeyeon , KANG, Sunhee , EWANN, Fanny, Anne , NAM, Ji, Youn , FENISTEIN, Denis, Philippe, Cedric , CHRISTOPHE, Thierry , CONTRERAS DOMINGUEZ, Monica , KIM, EunHye , HEO, Jamung
IPC分类号: C07D471/04 , C07D471/14 , A61K31/519 , A61P31/04 , A61P31/06
CPC分类号: C07D471/14 , C07D471/04
摘要: The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
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4.
公开(公告)号:EP2310388A2
公开(公告)日:2011-04-20
申请号:EP09776764.4
申请日:2009-06-17
发明人: BRODIN, Priscille , CHRISTOPHE, Thierry , NO, Zaesung , KIM, Jaeseung , GENOVESIO, Auguste , FENISTEIN, Denis, Philippe, Cedric , JEON, Heekyoung , EWANN, Fanny, Anne , KANG, Sunhee , LEE, Saeyeon , SEO, Min, Jung , PARK, Eunjung , CONTRERAS DOMINGUEZ, Monica , NAM, Ji, Youn , KIM, Eun, Hye
IPC分类号: C07D471/04 , A61K31/519 , A61P31/06
CPC分类号: C12Q1/18 , C07C255/66 , C07C335/40 , C07D223/24 , C07D233/84 , C07D251/52 , C07D251/66 , C07D271/113 , C07D401/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D498/04
摘要: The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
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公开(公告)号:EP1865320A3
公开(公告)日:2008-02-20
申请号:EP07252322.8
申请日:2007-06-08
发明人: Emans, Neil , Altschuler, Yoram , Kwon, Yongjun
IPC分类号: G01N33/50 , G01N33/74 , C07K14/705
CPC分类号: G01N33/5035 , G01N33/5008 , G01N33/566 , G01N2333/5754 , G01N2333/70571 , G01N2333/726 , G01N2800/12 , G01N2800/32
摘要: A method for identifying a compound that modifies the cellular distribution of a GPCR in a population of cells comprising:
a) taking a population of cells expressing a GPCR
b) incubating said cells with a candidate compound and with a ligand of the GPCR
c) determining distribution of said GPCR in cells treated according to step b) and comparing with distribution of GPCR in cells incubated with a ligand of the GPCR in the absence of the candidate compound;
wherein altered distribution in cells incubated with the candidate compound is indicative that the candidate compound modifies GPCR cellular distribution.-
公开(公告)号:EP3157904B1
公开(公告)日:2020-11-18
申请号:EP15730783.6
申请日:2015-06-22
发明人: KIM, Jaeseung , KANG, Sunhee , KANG, Juhee , LEE, Sumi , SEO, Jeong Jea , SEO, Mooyoung
IPC分类号: C07D215/48 , C07D495/04 , C07D277/82 , C07D513/04
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公开(公告)号:EP3157904A1
公开(公告)日:2017-04-26
申请号:EP15730783.6
申请日:2015-06-22
发明人: KIM, Jaeseung , KANG, Sunhee , KANG, Juhee , LEE, Sumi , SEO, Jeong Jea , SEO, Mooyoung
IPC分类号: C07D215/48 , C07D495/04 , C07D277/82 , C07D513/04
摘要: The present invention relates to small molecule compounds having the general formula (I): wherein A is a moiety selected from the group consisting of formulae (A) to (K) and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译: 本发明涉及具有通式(I)的小分子化合物:其中A是选自式(A) - (K)的部分及其在治疗细菌感染,特别是结核病中的用途。
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公开(公告)号:EP3027615A2
公开(公告)日:2016-06-08
申请号:EP14745158.7
申请日:2014-08-01
发明人: KIM, Jaeseung , KANG, Sunhee , SEO, Min Jung , SEO, Mooyoung , SEO, Jeongjea , LEE, Sumi , KANG, Juhee , PARK, Dongsik , KIM, Ryang Yeo , PETHE, Kevin , NAM, Kiyean , KIM, Jeongjun , OH, Soohyun , LEE, Saeyeon , AHN, Jiye
IPC分类号: C07D471/04
CPC分类号: C07D471/04
摘要: The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.
摘要翻译: 本发明涉及小分子化合物及其在治疗细菌感染,特别是结核病中的用途。
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公开(公告)号:EP2547678B1
公开(公告)日:2016-03-16
申请号:EP11711032.0
申请日:2011-03-18
发明人: NO, Zaesung , KIM, Jaeseung , BRODIN, Priscille Brodin , SEO, Min Jung , KIM, Young Mi , CECHETTO, Jonathan , JEON, Heekyoung , GENOVESIO, Auguste , LEE, Saeyeon , KANG, Sunhee , EWANN, Fanny Anne , NAM, Ji Youn , CHRISTOPHE, Thierry , FENISTEIN, Denis, Philippe, Cedric , JAMUNG, Heo , JIYEON, Jang
IPC分类号: C07D471/04 , C07D487/04 , A61K31/4188 , A61P31/06
CPC分类号: C07D401/04 , A61K31/437 , C07D471/04 , C07D487/04
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10.
公开(公告)号:EP2310388B1
公开(公告)日:2015-08-05
申请号:EP09776764.4
申请日:2009-06-17
发明人: BRODIN, Priscille , CHRISTOPHE, Thierry , NO, Zaesung , KIM, Jaeseung , GENOVESIO, Auguste , FENISTEIN, Denis, Philippe, Cedric , JEON, Heekyoung , EWANN, Fanny, Anne , KANG, Sunhee , LEE, Saeyeon , SEO, Min, Jung , PARK, Eunjung , CONTRERAS DOMINGUEZ, Monica , NAM, Ji, Youn , KIM, Eun, Hye
IPC分类号: C07D471/04 , A61K31/519 , A61P31/06
CPC分类号: C12Q1/18 , C07C255/66 , C07C335/40 , C07D223/24 , C07D233/84 , C07D251/52 , C07D251/66 , C07D271/113 , C07D401/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D498/04
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