公开(公告)号：EP2606154A4

公开(公告)日：2016-07-20

申请号：EP11818879

申请日：2011-08-20

申请人： INTEGENX INC

发明人： JOVANOVICH STEVAN B ,  STERN SETH ,  VAN GELDER EZRA ,  VANGBO MATTIAS

IPC分类号： C12Q1/70 ,  B01F3/00 ,  B01J19/00 ,  G01N1/00

CPC分类号： B01J19/0046 ,  B01J2219/00389 ,  B01J2219/00599 ,  B01J2219/00716 ,  B01J2219/00722 ,  B01L3/502738 ,  B01L7/52 ,  B01L2200/0647 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/043 ,  B01L2400/0481 ,  B01L2400/0655 ,  C12Q1/6806 ,  C12Q1/6869 ,  C12Q1/6874 ,  F16K99/0015 ,  F16K99/0059 ,  F16K2099/0084

摘要： The invention provides systems, devices, methods, and kits for performing an integrated analysis. The integrated analysis can include sample processing, library construction, amplification, and sequencing. The integrated analysis can be performed within one or more modules that are fluidically connected to each other. The one or more modules can be controlled and/or automated by a computer. The integrated analysis can be performed on a tissue sample, a clinical sample, or an environmental sample. The integrated analysis system can have a compact format and return results within a designated period of time.

公开(公告)号：EP2261650A2

公开(公告)日：2010-12-15

申请号：EP10011511.2

申请日：2005-09-15

申请人： IntegenX Inc.

发明人： Jovanovich, Stevan ,  Blaga, Luliu ,  Rank, David

IPC分类号： G01N27/447 ,  B01L3/00

CPC分类号： B01L3/50273 ,  B01F11/0071 ,  B01F13/0059 ,  B01J2219/005 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502761 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0654 ,  B01L2300/0803 ,  B01L2300/0806 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2300/1844 ,  B01L2400/0409 ,  B01L2400/0421 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/0638 ,  B01L2400/0655 ,  B01L2400/086 ,  C12Q2565/629 ,  G01N1/34 ,  G01N27/44721 ,  G01N27/44743 ,  G01N27/44791 ,  G01N35/0098

摘要： Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.

摘要翻译： 公开了用于将微芯片连接到各种类型的模块的方法和装置。 所公开的技术可用作各种应用的样品制备和分析系统，如DNA测序和基因分型，蛋白质组学，病原体检测，诊断和生物防治。

公开(公告)号：EP3341927B1

公开(公告)日：2024-06-19

申请号：EP16852780.2

申请日：2016-09-30

IPC分类号： G16B45/00 ,  G16B50/00 ,  G09B19/00 ,  G01N33/50 ,  C12Q1/68 ,  G06Q10/10

CPC分类号： G06Q10/101 ,  G16B45/00 ,  G16B50/00 ,  G16B50/20

公开(公告)号：EP3524973B1

公开(公告)日：2024-05-29

申请号：EP18248252.1

申请日：2016-06-15

IPC分类号： G01N27/447 ,  C12Q1/6874 ,  C12Q1/686 ,  B01L7/00 ,  G01N27/26 ,  F16K7/16 ,  F16K7/00 ,  F16K99/00 ,  B01L3/00

CPC分类号： B01L3/502738 ,  B01L3/502753 ,  B01L7/52 ,  B01L2200/0420130101 ,  B01L2200/066820130101 ,  B01L2200/1620130101 ,  B01L2300/081620130101 ,  B01L2400/04320130101 ,  B01L2400/047820130101 ,  F16K99/0015 ,  F16K99/0034 ,  F16K2099/007820130101 ,  F16K2099/008420130101 ,  B01L2300/088720130101 ,  B01L2300/12320130101 ,  B01L2400/065520130101 ,  B01F33/40 ,  B01F33/30

公开(公告)号：EP2606242A4

公开(公告)日：2016-07-20

申请号：EP11818878

申请日：2011-08-20

申请人： INTEGENX INC

发明人： VANGBO MATTIAS

IPC分类号： F15C3/04 ,  B01L3/00

CPC分类号： F16K99/0015 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2400/0638 ,  B01L2400/0655 ,  B33Y70/00 ,  B33Y80/00 ,  F04B19/006 ,  F04B43/043 ,  F16K99/0055 ,  F16K99/0059 ,  F16K2099/008 ,  F16K2099/0084 ,  F16K2099/0094 ,  Y10T137/0324 ,  Y10T137/0402 ,  Y10T137/7895

摘要： This invention provides a fluidic device comprising a diaphragm valve having a fluidics layer, an actuation layer and an elastic layer between the fluidics layer and the actuation layer, the elastic layer having a diaphragm that is mechanically sealed against the fluidics layer and the actuation layer by a sealing ring in the actuation layer.

公开(公告)号：EP2576022A2

公开(公告)日：2013-04-10

申请号：EP11787428.9

申请日：2011-05-26

申请人： Integenx Inc.

发明人： MAJLOF, Lars ,  VAN GELDER, Ezra

IPC分类号： B01D57/02

CPC分类号： G01N27/44708

摘要： A capillary electrophoresis device includes capillaries are thermally regulated on a thermally responsive electrical path attached to an electrically insulating circuit board. An optical scanner scans an array of capillaries. A laser, optical detector and optical selector are in an arrangement that allows the optical detector to selectively detect an optical signal from anyone or more of the plurality of electrophoresis capillaries.

公开(公告)号：EP2553423A1

公开(公告)日：2013-02-06

申请号：EP11763526.8

申请日：2011-04-01

申请人： Integenx Inc.

发明人： EBERHART, David ,  VAN GELDER, Ezra

IPC分类号： G01N15/06

CPC分类号： F16K99/0015 ,  B01J2219/00353 ,  B01J2219/00389 ,  B01J2219/00398 ,  B01J2219/00722 ,  B01L3/502707 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/123 ,  B01L2300/165 ,  B01L2400/0655 ,  C40B50/08 ,  C40B60/14 ,  F16K99/0059 ,  Y10T137/0318 ,  Y10T137/8593 ,  Y10T428/13 ,  Y10T428/1397

摘要： In one aspect this invention provides an article fabricated in one piece comprising at least one aperture through the piece, wherein the aperture defines a non-microfluidic volume, and a microfluidic channel formed in a surface of the piece onto which the aperture opens, wherein the channel is in fluidic communication with the aperture, wherein the aperture and the microfluidic channel define a fluidic circuit.

公开(公告)号：EP2261650A3

公开(公告)日：2011-07-06

申请号：EP10011511.2

申请日：2005-09-15

申请人： IntegenX Inc.

发明人： Jovanovich, Stevan ,  Blaga, Luliu ,  Rank, David

IPC分类号： G01N27/447 ,  B01L3/00

CPC分类号： B01L3/50273 ,  B01F11/0071 ,  B01F13/0059 ,  B01J2219/005 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/502761 ,  B01L7/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/0647 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/0654 ,  B01L2300/0803 ,  B01L2300/0806 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2300/1844 ,  B01L2400/0409 ,  B01L2400/0421 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/0638 ,  B01L2400/0655 ,  B01L2400/086 ,  C12Q2565/629 ,  G01N1/34 ,  G01N27/44721 ,  G01N27/44743 ,  G01N27/44791 ,  G01N35/0098

摘要： Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.

公开(公告)号：EP2438016B1

公开(公告)日：2021-06-02

申请号：EP10784213.0

申请日：2010-06-04

发明人： JOVANOVICH, Stevan, B. ,  NIELSEN, William, D. ,  COHEN, David, S. ,  RECKNOR, Michael ,  VANGBO, Mattias ,  VAN GELDER, Ezra ,  MAJLOF, Lars ,  EL-SISSI, Omar

IPC分类号： G01N35/00 ,  G01N27/447 ,  B01L3/00

公开(公告)号：EP3631432A1

公开(公告)日：2020-04-08

申请号：EP18732203.7

申请日：2018-05-22

申请人： Integenx Inc. ,  Life Technologies Corporation

发明人： LIU, Jen-Kuei ,  SOLANKI, Bharti ,  WENZ, Hans Michael ,  MERCER, Frank ,  AKIN, Cevat ,  KARGER, Achim ,  BARRON, Annelise ,  MACK, Scott

IPC分类号： G01N27/447