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公开(公告)号：EP3868414B1
公开(公告)日：2023-12-27
申请号：EP21169067.2
申请日：2016-11-08
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公开(公告)号：EP3262409B1
公开(公告)日：2020-03-25
申请号：EP16717475.4
申请日：2016-02-24
发明人： AUERBACH-NEVO, Tamar , ORR, Nadav , NUR, Israel
IPC分类号： G01N33/49 , C07K14/745 , C12N9/74 , A61K38/00
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公开(公告)号：EP3190981B1
公开(公告)日：2019-11-27
申请号：EP15797464.3
申请日：2015-09-09
发明人： ILAN, Erez , REGEV, Kfir , GURMAN, Yotam , TANNHAUSER, Robert J.
IPC分类号： A61B17/00
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公开(公告)号：EP3383298A1
公开(公告)日：2018-10-10
申请号：EP16813142.3
申请日：2016-12-01
发明人： PILPEL, Yair , DORON, Sivan , ZHERDEV, Yuri , LIOR, Erez , DEANGLIS, Ashley
摘要： The invention relates to syringes for storing and mixing components.
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公开(公告)号：EP3253870A1
公开(公告)日：2017-12-13
申请号：EP15880760.2
申请日：2015-02-06
发明人： WEISSMAN, Lior , SELLA, Dana , NUR, Israel , JIANG, Caixia , AN, Baochang
CPC分类号： C12N9/6429 , C12Y304/21005 , G01N33/84 , G01N33/86 , G01N2333/745
摘要： The present invention is directed to methods for the production of thrombin from a source of prothrombin using a given BaSO4 reagent as an adsorbent of prothrombin as well as methods for evaluating the suitability of a given BaSO4 reagent for use in preparation of thrombin. In at least one embodiment, the method includes contacting a sample of the given BaSO4 reagent with a source of prothrombin to obtain BaSO4-adsorbed prothrombin, and subsequently evaluating the pro-coagulant activity of the BaSO4-adsorbed prothrombin. In another embodiment, the method includes the step of evaluating relative to the pro-coagulant activity of normal mammalian plasma.
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公开(公告)号：EP2797649B1
公开(公告)日：2017-02-22
申请号：EP12823046.3
申请日：2012-12-20
发明人： MERON, Moti
CPC分类号： A61B17/00491 , A61B2017/00495 , A61M5/19 , A61M5/31511
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7.发明公开
公开(公告)号：EP3086817A1
公开(公告)日：2016-11-02
申请号：EP14830890.1
申请日：2014-12-04
发明人： PILPEL, Yair , DEANGLIS, Ashley , ZHERDEV, Yuri , DORON, Sivan , GORMAN, Anne J. , NUR, Israel
CPC分类号： A61K38/4846 , A61K31/194 , A61K31/198 , A61K33/14 , A61K38/1767 , A61K38/36 , A61K38/363 , A61K38/4833 , A61L24/0015 , A61L24/106 , A61L2300/254 , A61L2300/418 , C12Y304/21005 , C12Y304/21006 , C12Y304/21021 , C12Y304/21022
摘要： Provided herein is a single component sealant formulation (e.g. in a liquid form), methods for its preparation, and use. The formulation includes fibrinogen; vitamin K-dependent clotting zymogens comprising at least Factor II (FII) and Factor X (FX).
摘要翻译： 本文提供了单组分密封剂制剂（例如液体形式），其制备方法和用途。 该制剂包括纤维蛋白原; 至少包含因子II（FII）和因子X（FX）的维生素K依赖性凝血酶原酶。
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公开(公告)号：EP3074055A1
公开(公告)日：2016-10-05
申请号：EP14802208.0
申请日：2014-10-21
发明人： ILAN, Erez , GURMAN, Yotam , EAVRI, Ronen , DEKEL, Elya
CPC分类号： A61L15/44 , A61L15/28 , A61L15/38 , A61L2300/418 , C08L5/06
摘要： The present invention is directed to a dry pad comprising pectin, a divalent cation and thrombin and to its preparation. Preferably, the density of pectin in the dry pad of the invention ranges from about equal to or higher than 1% to lower than 7% (w/v). The pad according to the invention comprises pectin having a low methoxyl content.
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9.发明授权
公开(公告)号：EP2602316B1
公开(公告)日：2016-09-21
申请号：EP13157678.7
申请日：2008-08-29
发明人： Bechor, Edna , Bar, Liliana , Nur, Israel
CPC分类号： A61K35/16 , A61K35/545 , A61K38/1709 , A61K38/363 , A61L27/3616 , A61L27/3804 , A61L27/3856 , A61L27/3878 , A61L2430/38 , C12N5/0655 , C12N2500/84 , A61K2300/00
摘要： The invention relates to the use of viral inactivated-plasma cryoprecipitate concentrate (VIPCC) comprising a suitable fibronectin/fibrinogen ratio for treating, regenerating, repopulating injured Nucleus Pulposus cells/tissue, notochord derived tissue, and/or tissue whose formation is guided by notochordal cells, e.g. spinal intervertebral disc and/or central nervous system such as spine.
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公开(公告)号：EP2739642B1
公开(公告)日：2016-07-20
申请号：EP12746127.5
申请日：2012-06-26
CPC分类号： C12N9/50 , C07K1/22 , C07K14/81 , C07K14/811 , C12N9/6435 , C12Y304/21007
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