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公开(公告)号：EP4282883A3
公开(公告)日：2024-04-24
申请号：EP23194566.8
申请日：2015-07-31
IPC分类号： C07K7/06 , A61K35/12 , A61K35/14 , A61K38/00 , A61K39/395 , A61K48/00 , C12N5/10 , C12N15/09 , C07K7/08 , C07K16/28
CPC分类号： A61K38/00 , A61K39/395 , A61K48/00 , A61K35/12 , A61K35/14 , C07K16/28 , C07K7/06 , C07K7/08 , C12N5/10 , C12N15/09 , A61K39/0011 , A61K2039/515420130101 , A61K35/17
摘要： The present invention provides CDCA1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：EP3524677B1
公开(公告)日：2023-05-31
申请号：EP17858422.3
申请日：2017-10-04
IPC分类号： G01N33/532 , G01N33/68 , C07K16/28 , G01N33/574
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公开(公告)号：EP3360886B1
公开(公告)日：2023-01-25
申请号：EP16853677.9
申请日：2016-10-06
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公开(公告)号：EP3355699B1
公开(公告)日：2021-03-31
申请号：EP16852299.3
申请日：2016-09-12
发明人： MATSUO, Yo , HISADA, Shoji , NAKAMURA, Yusuke , CHAKRABARTI, Anjan , RAWAT, Manish , RAI, Sanjay , SATYANARAYANA, Arvapalli, Venkata , DUAN, Zhiyong , TALUKDAR, Arindam , RAVULA, Srinivas , DECORNEZ, Hélène
IPC分类号： A61P35/00 , A61K31/4745 , C07D519/00 , C07D487/04 , C07D471/04 , C07D451/00
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公开(公告)号：EP2895600B1
公开(公告)日：2020-02-19
申请号：EP13837757.7
申请日：2013-09-09
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公开(公告)号：EP3590954A2
公开(公告)日：2020-01-08
申请号：EP19186884.3
申请日：2015-07-31
IPC分类号： C07K7/06 , A61K35/12 , A61K35/14 , A61K39/00 , A61K48/00 , A61P35/00 , A61P37/04 , C07K7/08 , C07K16/18 , C12N5/10 , C12N15/09
摘要： The present invention provides KOC1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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公开(公告)号：EP3296317B1
公开(公告)日：2019-12-11
申请号：EP17198358.8
申请日：2012-10-25
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公开(公告)号：EP3524677A1
公开(公告)日：2019-08-14
申请号：EP17858422.3
申请日：2017-10-04
IPC分类号： C12N15/09 , C07K16/28 , C12P21/08 , G01N33/533 , G01N33/534 , G01N33/535 , G01N33/574
摘要： The present invention relates to monoclonal antibodies against FZD10. Furthermore, the present invention provides methods for diagnosing FZD10-related diseases using such an antibody, methods for detecting a FZD10 protein, methods for determining drug efficacy after treatment with FZD10 inhibitors, and methods of screening for subjects in whom treatment with FZD10 inhibitors is highly effective, and provides diagnostic reagents containing such an antibody.
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公开(公告)号：EP3208334B1
公开(公告)日：2019-07-03
申请号：EP17163532.9
申请日：2010-05-25
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公开(公告)号：EP3360886A1
公开(公告)日：2018-08-15
申请号：EP16853677.9
申请日：2016-10-06
IPC分类号： C07K7/06 , A61K35/12 , A61K35/17 , A61K38/00 , A61K48/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P11/00 , A61P13/08 , A61P13/10 , A61P13/12 , A61P15/00 , A61P19/00 , A61P35/00 , A61P35/02 , A61P37/04 , C12N5/10 , C12N15/09 , G01N33/15 , G01N33/50
CPC分类号： C07K7/06 , A61K35/12 , A61K35/15 , A61K35/17 , A61K38/00 , A61K39/00 , A61K48/00 , C07K14/4705 , C07K16/30 , C07K16/32 , C12N5/10 , G01N33/5047 , G01N33/505
摘要： The present invention provides FOXM1-derived epitope peptides having the ability to induce cytotoxic T cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic T cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or CTLs. The present invention also provides compositions and pharmaceutical compositions containing them as an active ingredient. Further, the present invention provides methods of treating and/or preventing cancer, and/or preventing postoperative recurrence thereof, using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells or pharmaceutical compositions of the present invention. Methods of inducing an immune response against cancer are also provided.
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