公开(公告)号：EP0649873B1

公开(公告)日：1997-02-12

申请号：EP94116490.7

申请日：1994-10-19

申请人： KURARAY Co. LTD.

发明人： Nakata, Hiromichi, c/o Kuraray Co. Ltd. ,  Hashimoto, Katsuya, c/o Kuraray Co. Ltd. ,  Masuda, Mikio, c/o Kuraray Co. Ltd. ,  Ishii, Masao, c/o Kuraray Co. Ltd.

IPC分类号： C08L53/02

CPC分类号： C08L53/025 ,  C08L2666/02

公开(公告)号：EP0751711A1

公开(公告)日：1997-01-08

申请号：EP94919067.0

申请日：1994-02-22

申请人： FRAZEE, Bradley C. ,  STUBBS, Clifford A. ,  Hix, Veldon Max ,  WILLARD, Miles J.

发明人： FRAZEE, Bradley C. ,  STUBBS, Clifford A. ,  Hix, Veldon Max ,  WILLARD, Miles J.

IPC分类号： A21D8 ,  A21D2 ,  A21D13 ,  A23L1

CPC分类号： A21D2/36 ,  A21D8/02 ,  A21D13/11 ,  A23L7/13 ,  A23L19/19

摘要： A process for forming a snack product and a snack formed therefrom with discontinuous characteristics (14, 16). The process includes forming a first highly cohesive dough and a second less cohesive dough matrix, combining the first and second discrete dough components into a composite dough sheet, cutting the dough sheet into a multiplicity of dough preforms, and frying the preforms to produce a snack with discontinuous characteristics (24).

摘要翻译： 一种形成具有不连续特征的小吃产品和小吃的方法（14,16）。 该方法包括形成第一高粘性面团和第二粘性较小的面团基质，将第一和第二离散面团组分组合成复合面团片，将面片切成多个面团预制体，并且将预制品煎炸以产生零食 具有不连续的特征（24）。

公开(公告)号：EP0707635A1

公开(公告)日：1996-04-24

申请号：EP94916144.0

申请日：1994-05-31

申请人： FAFF, Ortwin

发明人： FAFF, Ortwin

IPC分类号： G01N33 ,  C12N7 ,  C12Q1

CPC分类号： C12N7/00 ,  C12N2740/10051 ,  C12Q1/48 ,  C12Q1/702 ,  C12Q1/703 ,  Y10S435/961 ,  Y10S435/968 ,  Y10S435/974

摘要： A routine, direct and biochemically functional process is disclosed for detecting retrovirus in biological samples. For that purpose, structure-specific extraction with immobilised ligands directed against the viral surface is combined with function-specific enzyme reaction for retrovirus by means of reverse transcriptase, RNAse H, integrase or protease. Reverse transcription by means of reverse transcriptase, retroviral RNA and tRNA is particularly suitable for the retrovirus-specific enzyme reaction. In an ulterior detection step, the newly synthesised cDNA products are identified by radioactive, photometric, luminescent or fluorescent processes. This process represents a biochemical simulation of the natural process of retroviral infection and development within the cell (reverse transcription, integration, maturation) and allows several retroviral components, surface glycoproteins, enzymes, structural proteins, RNA and tRNA to be simultaneously detected. A process with a qualitatively improved specificity compared with state-of-the-art processes is thus obtained. The process takes 1-2 days, may be easily and routinely carried out in a microtiter format and thus allows many probes to be simultaneously processed within a short time. In addition, the process may be universally applied to all species of retrovirus by means of corresponding specific ligands. The process is suitable for detecting retrovirus for the purpose of diagnosing, following and treating viral diseases, in transfusion and transplantation medicine, in virological research and development and for the biological quality control of pharmaceutical and biotechnological products.

公开(公告)号：EP0657557A1

公开(公告)日：1995-06-14

申请号：EP94117353.6

申请日：1994-11-03

申请人： KABUSHIKI KAISHA KOBE SEIKO SHO

发明人： Kawaguchi, Yasunobu, c/o Kobe Works ,  Shimotsusa, Masataka, c/o Kobe Works ,  Momozaki, Kan, c/o Kobe Works ,  Nakayama, Takenori, c/o Kobe Corporate Res. Lab. ,  Miyauchi, Shigeaki, c/o Kobe Corporate Res. Lab. ,  Yamamoto, Yoshinori, c/o Kobe Works ,  Ohkouchi, Norio, c/o Kobe Works

IPC分类号： C22C38/02 ,  C22C38/18 ,  C22C38/22 ,  C22C38/40

CPC分类号： C22C38/34 ,  C21D8/065 ,  C21D9/02 ,  C22C38/02 ,  C22C38/46 ,  Y10S148/908

摘要： Disclosed is a spring steel for a high corrosion resistance and high strength, which exhibits an excellent drawability without softening heat treatment after hot rolling, and which has a strength of 1900 MPa or more by quenching and tempering and an excellent corrosion resistance. The spring steel contains, in mass %, 0.3-0.6% C, 1.0-3.0% Si, 0.1-0.5% Mn and 0.5-1.5% Cr, and 1.0% or less (excluding 0%) Ni and/or 0.1-0.5% Mo, the balance being essentially Fe and inevitable impurities, wherein the elements satisfy the following requirement:

2.5 ≦ (FP) ≦ 4.5
2.0 ≦ (FP/log D) ≦ 4.0

   where D is a diameter (mm) of the rolled material, and FP = (0.23[C]+0.1)×(0.7[Si]+1)×(3.5[Mn]+1) ×(2.2[Cr]+1)×(0.4[Ni]+1)×(3[Mo]+1) in which [element] represents mass % of the element.

摘要翻译： 公开了一种高耐腐蚀性和高强度的弹簧钢，其在热轧后没有软化热处理的情况下具有优异的拉伸性，通过淬火回火和优异的耐腐蚀性而具有1900MPa以上的强度。 弹簧钢以质量％计含有0.3-0.6％的C，1.0-3.0％的Si，0.1-0.5％的Mn和0.5-1.5％的Cr，以及1.0％以下（不包括0％）的Ni和/或0.1-0.5 ％Mo，余量基本上为Fe和不可避免的杂质，其中元素满足以下要求：2.5

公开(公告)号：EP0516138B1

公开(公告)日：1995-02-01

申请号：EP92109075.9

申请日：1992-05-29

申请人： GORDEX CORPORATION

发明人： Saita, Tateji

IPC分类号： A22C17/00

CPC分类号： A22C21/0053 ,  A22C21/0076

公开(公告)号：EP0630981A1

公开(公告)日：1994-12-28

申请号：EP94903030.8

申请日：1993-12-21

申请人： MITSUBISHI MATERIALS CORPORATION

发明人： CHO, Toshiyuki, Chuo-Kenkyusho ,  SHIRAISHI, Yoshimasa, Chuo-Kenkyusho ,  TAKAHASHI, Tsutomu, Chuo-Kenkyusho ,  WATANABE, Masato, Kitamoto-Plant

IPC分类号： C22C9/00 ,  F16L9/02

CPC分类号： C22C9/00

摘要： A cold- and hot-water piping made of a pitting-resistant copper alloy which contains niobium and/or tantalum in a total amount of 0.005-5 wt. %, further contains, if necessary, at least one element selected from among: (i) yttrium and/or zirconium in a total amount of 0.005-1 wt. %, (ii) tin and/or silver in a total amount of 0.05-5 wt. %, (iii) at least one element selected from the group consisting of titanium and R (rare earth elements other than yttrium) in a total amount of 0.005-1 wt. %, and (iv) tungsten in an amount of 0.003-0.5 wt. %, and still further contains, if necessary, phosphorus in an amount of 0.005-0.5 wt. %.

摘要翻译： 由耐点蚀铜合金制成的冷热水管道，其含有总量为0.005-5重量％的铌和/或钽。 ％，如果需要，还含有至少一种选自以下的元素：（i）总量为0.005-1重量％的钇和/或锆。 ％，（ii）锡和/或银，总量为0.05-5wt。 ％，（iii）选自钛和R（除了钇之外的稀土元素）中的至少一种元素，总量为0.005-1wt。 ％，和（iv）0.003-0.5重量％的钨。 ％，如果需要，还含有0.005-0.5重量％的磷。 ％。

公开(公告)号：EP0627399A1

公开(公告)日：1994-12-07

申请号：EP94108491.5

申请日：1994-06-01

申请人： KURARAY CO., LTD.

发明人： Omatsu, Toshihiro ,  Tokitoh, Yasuo

IPC分类号： C07C45/49 ,  C07C47/19 ,  C07C29/141 ,  C07C31/22

CPC分类号： C07C29/141 ,  C07C31/22 ,  C07C45/49 ,  C07C47/19

摘要： A process for producing 2-formyl-1,4-butanediol comprises effecting reaction of 2-butene-1,4-diol with hydrogen and carbon monoxide in the presence of:

(a) a rhodium compound,
(b) a tris(substituted aryl) phosphite having an electronic parameter, ν-value, of 2,080 to 2,090 cm⁻¹ and a steric parameter, ϑ-value, of 135 to 190° and being represented by the formula P(OR)₃
wherein each of R's, which may be the same or different, represents a substituted aryl group having at least 7 carbon atoms, and
(c) a bis(diphenylphosphino)alkane represented by the formula Ph₂P-(CH₂)n-PPh₂ wherein n is an integer of 2 to 6, and
at a temperature of not more than 80°C.

摘要翻译： 一种生产2-甲酰基-1,4-丁二醇的方法包括：在（a）铑化合物，（b）三（取代的）存在下，使2-丁烯-1,4-二醇与氢气和一氧化碳反应： 芳基）亚磷酸酯，nu值为2,080至2,090cm -1，空间参数，θ值为135至190℃，并由式P（OR）3表示，其中每个 R（其可以相同或不同）表示具有至少7个碳原子的取代的芳基，和（c）由式Ph2P-（CH2）n-PPh2表示的双（二苯基膦基）烷烃，其中n是整数 为2〜6，温度为80℃以下

公开(公告)号：EP0591955A3

公开(公告)日：1994-05-18

申请号：EP93116187.1

申请日：1993-10-06

申请人： Naito, Shizu

发明人： Naito, Hiroyuki

IPC分类号： C08L83/04 ,  C09D183/04 ,  C08K5/55 ,  C08K5/56 ,  C08K5/05 ,  C08K5/00

CPC分类号： C08K5/55 ,  C08G77/12 ,  C08G77/16 ,  C08G77/18 ,  C08K5/0025 ,  C08L83/04 ,  C09D183/04 ,  Y10T428/31663 ,  C08L2666/44 ,  C08L83/00 ,  C08L2666/28 ,  C08L2666/52

摘要： A solvent-free ternary organosiloxane composition is disclosed, which contains (A) liquid organopolysiloxane, (B) a cross-linking agent, and (C) a curing catalyst and, optionally, (D) a filler, said organopolysiloxane (A) being constituted by organosilicon group of X-Si (wherein X represents a hydrogen atom or a monovalent hydrocarbyl group) and functional side chain of OR (wherein R represents a hydrogen atom, a C₁ - C₅ alkyl group or an acyl group), said cross-linking agent (B) being one or more organometallic compounds selected from the group consisting of an organoaluminum compound, an organoboron compound, an organosilicon compound, an organotitanium compound and an organozirconium compound having at least one functional group selected from the group consisting of an alkoxy group, an acyloxy group and an oxime group, and said curing catalyst (C) being a metal-containing organic compound, with the total contents of the metal elements of the ternary composition being 25 % by weight to less than 40 % by weight in terms of MO y/2 (wherein M represents aluminum, boron, silicon, titanium or zirconium, and y represents a valency of the metal element). A shaped polymer composition, an adhesive polymer composition, a composite structure, a composite sheet and a building material using the solvent-free organosiloxane composition are also disclosed.

公开(公告)号：EP0562583A1

公开(公告)日：1993-09-29

申请号：EP93104890.4

申请日：1993-03-24

申请人： LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d.

发明人： Copar, Anton, Dr. Ing.

IPC分类号： C07D498/047

CPC分类号： C07D503/00

摘要： Es wird ein neues Verfahren zur Herstellung von Clavulansäure und deren pharmazeutisch annehmbaren Salzen wie Kalium-clavulanat beschrieben. Demgemäss wird rohe Clavulansäure, die in der Form eines Extraktes in einem organischen Lösungsmittel wie Ethylacetat vorliegt, welcher Extrakt auf bekannte Weise nach der Fermentation mit einem Clavulansäure produzierenden Mikroorganismus erhalten wurde, mit substituierten Alkylendiaminen der Formel II

worin die Substituenten R₁, R₂, R₃, R₄ und R₅ sowie n die im Anspruch 1 genannten Bedeutungen besitzen, z.B. mit N,N'-Diisopropylethylendiamin, zu neuen Alkylendiammonium-clavulanaten der Formel I

worin die Substituenten R₁, R₂, R₃, R₄ und R₅ sowie n die im Anspruch 1 genannten Bedeutungen besitzen, z.B. zu N,N'-Diisopropylethylendiammonium-diclavulanat, umgesetzt. Die erhaltenen Verbindungen der Formel I werden gegebenenfalls isoliert und mti Alkalisalzen von Alkansäuren, z.B. mit Kalium-2-ethyl-hexanoat in Isopropanol, zu Kalium-clavulanat umgesetzt.
Wegen der hemmenden Wirkung auf β-Lactamasen und einer signifikanten synergistischen Wirkung in Kombination mit β-Lactam-Antibiotika aus der Reihe der Penicilline und Cephalosporine sind die Clavulansäure und deren pharmazeutisch annehmbare Salze wertvolle Verbindungen zur Herstellung von galenischen Präparaten, die gegen durch zahlreiche Gram-positive und Gram-negative Mikroorganismen verursachte Infektionskrankheiten wirksam sind.

摘要翻译： 它是用于制备棒酸及其药学如克拉维酸钾描述上可接受的盐的新方法。 因此，粗克拉维酸，这是一种提取物的形式在有机溶剂如乙酸乙酯，将其以已知的方式与克拉维酸的微生物发酵后得到的提取物，与式II 其中取代基R1，R2的取代的亚烷基二胺 ，R3，R4和R5和n具有权利要求1中给出的含义，包括 与N，N'-二异丙基乙二胺，式新Alkylendiammonium-clavulanaten I 其中取代基R1，R2，R3，R4和R5和n具有权利要求1中，例如在给定的含义 到N，N'- diisopropylethylenediammonium二棒酸盐实现。 我所得到的式I的化合物是任选地分离和MTI的链烷酸，例如碱金属盐 用氢-2-乙基 - 己酸于异丙醇中以克拉维酸钾反应。 因为β内酰胺酶的抑制活性，并结合β内酰胺抗生素从系列青霉素和头孢菌素的显著协同作用的是克拉维酸及其药学上可接受的盐是用于制备药物制剂的针对多种革兰氏有价值的化合物 阳性和革兰氏阴性微生物引起的感染性疾病是有效的。

公开(公告)号：EP0540854A3

公开(公告)日：1993-07-28

申请号：EP92115434.0

申请日：1992-09-09

申请人： Sansho Seiyaku Co., Ltd.

发明人： Hanada, Seigo ,  Yamamoto, Shinji

IPC分类号： A61K7/06

CPC分类号： A61K8/606 ,  A61K8/42 ,  A61K8/4926 ,  A61K8/4953 ,  A61Q7/00

摘要： A preparation for promoting hair growth is disclosed, which contains as an effective ingredient or ingredients one or more compounds selected from the group consisting of purine compounds, pyridylurea compounds, diphenylurea compounds, pyrimidine compounds, imidazole compounds, benzoylaminourea compounds and 4- substituted aminopyrrolo[2,3-d]pyrimidine compounds. This preparation exhibits an excellent effect of promoting hair growth or curing alopecia such as male alopecia or alopecia areata. Of the effective compounds, purine compounds and pyridyl compounds exhibit particularly remarkable effects.