Treatment of viral disease by glycosides
    2.
    发明公开
    Treatment of viral disease by glycosides 失效
    治疗糖尿病的病毒

    公开(公告)号:EP0442744A3

    公开(公告)日:1992-07-15

    申请号:EP91301212.6

    申请日:1991-02-14

    IPC分类号: A61K31/585 A61K31/705

    摘要: A use of a compound of the formula:

    wherein
    R₁, R₂, R₃ and R₄ are independently hydrogen atom or hydroxy group,
    R₅ is hydrogen atom, methyl, hydroxymethyl, or formyl group,
    R₆ is hydrogen atom or methyl group,
    R₇ is 2,5-dihydro-2-oxofuran-4-yl group, or 2-oxo-2H-pyran-4-yl group, and
    R₈ is hydrogen atom or sugar group,
    with the proviso that, when R₇ is 2,5-dihydro-2-oxofuran-4-yl, then R₈ is not hydrogen atom,
    or a 4,5-unsaturated compound corresponding thereto, as an active ingredient, for the manufacture of a medicament for the treatment of viral diseases.

    Image forming method
    3.
    发明公开
    Image forming method 失效
    成像方法

    公开(公告)号:EP0487797A1

    公开(公告)日:1992-06-03

    申请号:EP90312948.4

    申请日:1990-11-28

    发明人: Tsuchiko, Susumu

    IPC分类号: G03F3/10 G03F7/075

    CPC分类号: G03F3/106 G03F7/0757

    摘要: An image forming method using an image-forming material comprising a first substrate, a photosensitive layer, an ink layer which contains colorant and undergoes cohesive failure under thermal separation, and a second substrate, the method comprising the steps of:

    (a) imagewise exposing the photosensitive layer on which an original image is placed,
    (b) separating the second substrate under heat such that the part of the ink layer which is on an exposed portion of the photosensitive layer is retained and the part of the ink layer which is positioned on a nonexposed portion of the photosensitive layer is removed together with the second substrate, and
    (c) bringing that part of the ink layer which is retained on the exposed portion of the photosensitive layer into contact with an image receptor under pressure such that the part of the ink layer which is retained on the exposed portion is transferred to the image receptor.

    摘要翻译: 一种图像形成方法,该图像形成方法使用包含第一基材,感光层,含有着色剂并在热分离时发生内聚破坏的油墨层和第二基材的成像材料,该方法包括以下步骤:(a)成像曝光 在其上放置原始图像的感光层,(b)在加热下分离第二基板,使得位于感光层的曝光部分上的油墨层的部分被保留,并且位于油墨层的一部分 (c)在压力下使保留在光敏层的曝光部分上的油墨层的该部分与图像接收器接触,使得该部分油墨层在压力下与图像接收器接触, 保留在曝光部分上的油墨层被转印到图像接收器。

    5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives
    8.
    发明公开
    5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives 失效
    (咪唑)甲基-3,3-二取代-2(3H)呋喃酮衍生物

    公开(公告)号:EP0455909A2

    公开(公告)日:1991-11-13

    申请号:EP90312633.2

    申请日:1990-11-20

    摘要: Furanone compounds and compositions having anticholinergic activity are described. The compounds have the formula:
    wherein:

    the dashed line indicates either the 4,5-unsaturated or the 4,5-dihydrofuranone ring;
    R and R 2 may be the same or different and are hydrogen, thienyl, furanyl, or cycloalkyl (C 3 -C 6 ), benzyl, phenyl, substituted phenyl or substituted benzyl wherein the phenyl or benzyl group may be substituted with halogen, trifluoromethyl, lower alkyl, lower alkoxy or hydroxy;
    Ra, R 4 and R 5 may be the same or different and are hydrogen, lower alkyl, lower alkyl substituted with a halogen, alkoxy, amino or carboxylic acid group, an alkyl or alkylene bridge between R 4 and R 5 or R 3 and the ring N, trifluoromethyl, nitro, a cycloalkyl group containing 3 to 6 carbons, halogen, benzyl, phenyl, substituted phenyl or substituted benzyl, for which the substituents are the same as those set forth for R 1 and R 2 substituted benzyl or phenyl.
    R 6 in the dihydrofuranone series is hydrogen or lower alkyl.

    Also described are the pharmaceutically acceptable quaternary alkyl and acid addition salts of such compounds The compounds are cholinergic receptor antagonists, and are particulary useful in the treatment of neurogenic bladder disorder and chronic obstructive pulmonary diseases.

    摘要翻译: 描述了具有抗胆碱能活性的呋喃酮化合物和组合物。 该化合物具有下式:其中:虚线表示4,5-不饱和或4,5-二氢呋喃酮环; R 1和R 2可以相同或不同,为氢,噻吩基,呋喃基或环烷基(C3-C6),苄基,苯基,取代的苯基或取代的苄基,其中苯基或苄基可被卤素,三氟甲基,低级烷基 ,低级烷氧基或羟基; R 3,R 4和R 5可以相同或不同,为氢,低级烷基,被卤素,烷氧基,氨基或羧酸基取代的低级烷基,R 4和R 5或R 3之间的烷基或亚烷基桥和环N,三氟甲基 硝基,含有3至6个碳原子的环烷基,卤素,苄基,苯基,取代的苯基或取代的苄基,其取代基与对R 1和R 2取代的苄基或苯基所述相同。 二氢呋喃酮系中的R6为氢或低级烷基。 还描述了这些化合物的药学上可接受的季烷基和酸加成盐。化合物是胆碱能受体拮抗剂,特别可用于治疗神经源性膀胱病和慢性阻塞性肺疾病。

    Curing resin and curing resin-composition
    9.
    发明公开
    Curing resin and curing resin-composition 失效
    固化树脂和固化树脂组合物

    公开(公告)号:EP0373925A3

    公开(公告)日:1991-09-18

    申请号:EP89313054.2

    申请日:1989-12-13

    IPC分类号: C08F8/14 C08F8/30 C09D145/00

    摘要: A curing resin obtained in the following manner, 100 parts by weight of at least one material (component A) selected from the group consisting of a five-membered cyclic compound having conjugated double bonds which is represented by the general formula:
    wherein R represents alkyl having 1 to 3 carbon atoms, and m and n stand for 0 or for an integer of 1 to 6 and m+n = 6,
    and addition products thereof formed by the Diels-Alder reaction, 0 to 50 parts by weight of an aromatic compound (component A′) having at least one polymerizable carbon-­carbon double bond and 2 to 120 parts by weight of a compound (component B) having at least one polymerizable carbon-carbon double bond and at least one hydroxy group are polymerized under heating; the obtained cyclopenta­diene resin (R1) having hydroxy groups and/or the resin (R1′) having hydroxy groups obtained by selective hydr­ogenation of only the double bonds in the said resin (R1) is reacted with a polyisocyanate compound (component C) at an equivalent ratio of the isocyanate groups in the component C in the range of 0.02 to 0.95 based on the hydroxy groups in the resin R1 and/or R1′; the thus obtained resin (R2) is then esterified with an α,β-un­saturated carboxylic acid (component D) at an equivalent ratio of carboxyl groups in the component D in the range of 0.1 to 1.1 based on the hydroxy groups in the resin (R2).

    摘要翻译: 以下列方式获得的固化树脂:100重量份选自由以下通式表示的具有共轭双键的五元环状化合物组成的组中的至少一种材料(组分A):其中CH R表示碳原子数1〜3的烷基,m和n表示0或1〜6的整数,m + n = 6,通过Diels-Alder反应形成的加成物0〜50重量份 具有至少一个可聚合碳 - 碳双键的芳族化合物(组分A min)和具有至少一个可聚合碳 - 碳双键和至少一个羟基的化合物(组分B)2至120重量份 加热聚合; 所获得的具有羟基的所得环戊二烯树脂(R1)和/或具有羟基的树脂(R1min)仅通过在所述树脂(R1)中的双键进行选择氢化而与多异氰酸酯化合物(组分C)反应, 基于树脂R1中的羟基和/或R1min,组分C中异氰酸酯基的当量比在0.02至0.95的范围内; 然后将如此得到的树脂(R2)用α,β-不饱和羧酸(组分D)以相对于树脂中的羟基为基准,组分D中羧基的当量比为0.1〜1.1, R2)。

    Soft magnetic alloy films and magnetic heads using the same
    10.
    发明公开
    Soft magnetic alloy films and magnetic heads using the same 失效
    WeichmagnetischeDünnschichtenaus Legierung undMagnetköpfedaraus。

    公开(公告)号:EP0442760A2

    公开(公告)日:1991-08-21

    申请号:EP91301266.2

    申请日:1991-02-18

    摘要: The invention provides a soft magnetic alloy film consisting essentially of an average composition of the following formula T a M b X c N d wherein T represents at least one metal selected from the group consisting of Fe, Co and Ni, M represents at least one metal selected from the group consisting of Nb, Zr, Ti, Ta, Hf, Cr, Mo, W and Mn, X represents at least one metalloid selected from the group consisting of B, Si, Ge and C, N is nitrogen, and a, b, c and d are, respectively, such values by atomic percent that
       65 ≦ a ≦ 93
       0 ≦ b ≦ 20
       0 ≦ c ≦ 20
       1 ≦ d ≦ 20
       5 ≦ b + c
       a + b + c + d = 100
    The soft magnetic thin film has an axis of easy magnetization in a direction vertical to the film surface. The nitride alloy film may be compositionally modulated in order to further improve soft magnetic characteristics. The axis of easy magnetization can be imparted by thermally treating the film while applying a magnetic field in a direction vertical to the film surface. Magnetic heads using the film are also described.

    摘要翻译: 本发明提供了一种软磁合金膜,其基本上由下式的平均组成组成:其中T表示选自Fe,Co和Ni中的至少一种金属,M表示选自以下的金属中的至少一种金属: 由Nb,Zr,Ti,Ta,Hf,Cr,Mo,W和Mn组成,X表示选自B,Si,Ge和C中的至少一种准金属,N为氮,a,b,c 和d分别为原子百分比的这样的值,即65