摘要:
There is provided an inhibitory agent for the inhibition of increases in blood sugar level, comprising at least one of conduritol A of the formula (I):
wherein R₁, R₂, R₃ and R₄ are independently hydrogen atom or hydroxy group, R₅ is hydrogen atom, methyl, hydroxymethyl, or formyl group, R₆ is hydrogen atom or methyl group, R₇ is 2,5-dihydro-2-oxofuran-4-yl group, or 2-oxo-2H-pyran-4-yl group, and R₈ is hydrogen atom or sugar group, with the proviso that, when R₇ is 2,5-dihydro-2-oxofuran-4-yl, then R₈ is not hydrogen atom, or a 4,5-unsaturated compound corresponding thereto, as an active ingredient, for the manufacture of a medicament for the treatment of viral diseases.
摘要:
An image forming method using an image-forming material comprising a first substrate, a photosensitive layer, an ink layer which contains colorant and undergoes cohesive failure under thermal separation, and a second substrate, the method comprising the steps of:
(a) imagewise exposing the photosensitive layer on which an original image is placed, (b) separating the second substrate under heat such that the part of the ink layer which is on an exposed portion of the photosensitive layer is retained and the part of the ink layer which is positioned on a nonexposed portion of the photosensitive layer is removed together with the second substrate, and (c) bringing that part of the ink layer which is retained on the exposed portion of the photosensitive layer into contact with an image receptor under pressure such that the part of the ink layer which is retained on the exposed portion is transferred to the image receptor.
摘要:
A substrate is provided with at least a magnetooptical recording layer and a protective layer to form a magnetooptical recording medium. The surface of the protective layer is coarsened in a peripheral direction. This recording medium gives good floating conditions to a magnetic head to write data.
wherein R₁ to R₁₂ each denote a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, and X denotes an oxygen atom, a sulfur atom, a methylene group or an ethylene group.
摘要:
A thermoplastic resin-based functional film obtained by a process which comprises the following steps either A or B and C:
A. mixing 10 to 95 parts by weight of a thermoplastic resin (a) having a melting point or melting starting temperature Tm a , 5 to 150 parts by weight, per 100 parts by weight of said thermoplastic resin (a), of a solvent (c) and 5 to 90 parts by weight of a functional substance having a property-change temperature Tb equal to or lower than Tm a at a temperature lower than Tb to form a mixture, keeping the mixture at a temperature lower than Tb for at least 10 minutes, kneading the mixture at a temperature lower than Tb into a substantially uniform kneaded mixture and shaping the substantially uniform kneaded mixture into a film at a temperature lower than Tb, B. preliminarily mixing 10 to 95 parts by weight of a thermoplastic resin (a) having a melting point or melting starting temperature Tm a and 5 to 150 parts by weight, per 100 parts by weight of said thermoplastic resin (a), of a solvent (c) at a temperature lower than Tm a , keeping the resultant preliminary mixture at a temperature lower than Tm a for at least 10 minutes, adding 5 to 90 parts by weight of a functional substance having a property-change temperature Tb equal to or lower than Tm a to the above preliminary mixture, kneading the resultant mixture at a temperature lower than Tb to form a substantially uniform kneaded mixture and shaping the substantially uniform kneaded mixture into a film, and C. removing the solvent (c) from the film.
摘要:
There is provided an inhibitory agent for the inhibition of increases in blood sugar level, comprising at least one of conduritol A of the formula (I):
摘要:
Furanone compounds and compositions having anticholinergic activity are described. The compounds have the formula: wherein:
the dashed line indicates either the 4,5-unsaturated or the 4,5-dihydrofuranone ring; R and R 2 may be the same or different and are hydrogen, thienyl, furanyl, or cycloalkyl (C 3 -C 6 ), benzyl, phenyl, substituted phenyl or substituted benzyl wherein the phenyl or benzyl group may be substituted with halogen, trifluoromethyl, lower alkyl, lower alkoxy or hydroxy; Ra, R 4 and R 5 may be the same or different and are hydrogen, lower alkyl, lower alkyl substituted with a halogen, alkoxy, amino or carboxylic acid group, an alkyl or alkylene bridge between R 4 and R 5 or R 3 and the ring N, trifluoromethyl, nitro, a cycloalkyl group containing 3 to 6 carbons, halogen, benzyl, phenyl, substituted phenyl or substituted benzyl, for which the substituents are the same as those set forth for R 1 and R 2 substituted benzyl or phenyl. R 6 in the dihydrofuranone series is hydrogen or lower alkyl.
Also described are the pharmaceutically acceptable quaternary alkyl and acid addition salts of such compounds The compounds are cholinergic receptor antagonists, and are particulary useful in the treatment of neurogenic bladder disorder and chronic obstructive pulmonary diseases.
摘要翻译:描述了具有抗胆碱能活性的呋喃酮化合物和组合物。 该化合物具有下式:其中:虚线表示4,5-不饱和或4,5-二氢呋喃酮环; R 1和R 2可以相同或不同,为氢,噻吩基,呋喃基或环烷基(C3-C6),苄基,苯基,取代的苯基或取代的苄基,其中苯基或苄基可被卤素,三氟甲基,低级烷基 ,低级烷氧基或羟基; R 3,R 4和R 5可以相同或不同,为氢,低级烷基,被卤素,烷氧基,氨基或羧酸基取代的低级烷基,R 4和R 5或R 3之间的烷基或亚烷基桥和环N,三氟甲基 硝基,含有3至6个碳原子的环烷基,卤素,苄基,苯基,取代的苯基或取代的苄基,其取代基与对R 1和R 2取代的苄基或苯基所述相同。 二氢呋喃酮系中的R6为氢或低级烷基。 还描述了这些化合物的药学上可接受的季烷基和酸加成盐。化合物是胆碱能受体拮抗剂,特别可用于治疗神经源性膀胱病和慢性阻塞性肺疾病。
摘要:
A curing resin obtained in the following manner, 100 parts by weight of at least one material (component A) selected from the group consisting of a five-membered cyclic compound having conjugated double bonds which is represented by the general formula: wherein R represents alkyl having 1 to 3 carbon atoms, and m and n stand for 0 or for an integer of 1 to 6 and m+n = 6, and addition products thereof formed by the Diels-Alder reaction, 0 to 50 parts by weight of an aromatic compound (component A′) having at least one polymerizable carbon-carbon double bond and 2 to 120 parts by weight of a compound (component B) having at least one polymerizable carbon-carbon double bond and at least one hydroxy group are polymerized under heating; the obtained cyclopentadiene resin (R1) having hydroxy groups and/or the resin (R1′) having hydroxy groups obtained by selective hydrogenation of only the double bonds in the said resin (R1) is reacted with a polyisocyanate compound (component C) at an equivalent ratio of the isocyanate groups in the component C in the range of 0.02 to 0.95 based on the hydroxy groups in the resin R1 and/or R1′; the thus obtained resin (R2) is then esterified with an α,β-unsaturated carboxylic acid (component D) at an equivalent ratio of carboxyl groups in the component D in the range of 0.1 to 1.1 based on the hydroxy groups in the resin (R2).
摘要:
The invention provides a soft magnetic alloy film consisting essentially of an average composition of the following formula T a M b X c N d wherein T represents at least one metal selected from the group consisting of Fe, Co and Ni, M represents at least one metal selected from the group consisting of Nb, Zr, Ti, Ta, Hf, Cr, Mo, W and Mn, X represents at least one metalloid selected from the group consisting of B, Si, Ge and C, N is nitrogen, and a, b, c and d are, respectively, such values by atomic percent that 65 ≦ a ≦ 93 0 ≦ b ≦ 20 0 ≦ c ≦ 20 1 ≦ d ≦ 20 5 ≦ b + c a + b + c + d = 100 The soft magnetic thin film has an axis of easy magnetization in a direction vertical to the film surface. The nitride alloy film may be compositionally modulated in order to further improve soft magnetic characteristics. The axis of easy magnetization can be imparted by thermally treating the film while applying a magnetic field in a direction vertical to the film surface. Magnetic heads using the film are also described.
摘要翻译:本发明提供了一种软磁合金膜,其基本上由下式的平均组成组成:其中T表示选自Fe,Co和Ni中的至少一种金属,M表示选自以下的金属中的至少一种金属: 由Nb,Zr,Ti,Ta,Hf,Cr,Mo,W和Mn组成,X表示选自B,Si,Ge和C中的至少一种准金属,N为氮,a,b,c 和d分别为原子百分比的这样的值,即65 = 93 0 = = 0 = / = b + ca + b + c + d = 100软磁性薄膜在垂直于膜表面的方向上具有容易磁化的轴。 氮化物合金膜可以被组成调制以进一步改善软磁特性。 可以通过在垂直于膜表面的方向施加磁场的同时对膜进行热处理来赋予容易磁化的轴。 还描述了使用该膜的磁头。