公开(公告)号：EP0331710B1

公开(公告)日：1994-04-27

申请号：EP88908482.8

申请日：1988-08-08

申请人： CANOPY EDGE, INC.

发明人： Calderon, Reynaldo

IPC分类号： A61M25/00

CPC分类号： A61M25/00 ,  A61M1/3615 ,  A61M25/0026 ,  A61M25/1011 ,  A61M37/00 ,  A61M2025/09183 ,  A61M2025/1015

摘要： Tumors in the body of a patient are studied in situ by a monitor (12), such as computer assisted tomography, X-ray or the like, while optimal flow paths through the tumor area are established. A catheter (52) with a suction lumen (50) and an infusion lumen (25), with seals (22, 56) associated with each, is placed in the patient's vein near the tumor. Flow is then sealed in the vein with the infusion seal (56). A carrier medium dye is injected into the tumor at selected flow rates and differential pressures. Flow of the dye through the tumor is observed on the monitor (12) to determine optimal retrograde perfusion paths through the tumor for the selected flow rates and differential pressures. Once the optimal perfusion paths are noted, microspheres with active ingredients, such as chemotherapy, can be selectively perfused through each of the paths in the tumor at desired flow rates, pressures and active ingredient dosages.